A5063893104- RNA modifications and cancer
- Ferroptosis and cancer prognosis
- Autophagy in Disease and Therapy
- Amyotrophic Lateral Sclerosis Research
- Mitochondrial Function and Pathology
- Inflammatory mediators and NSAID effects
- Neurogenetic and Muscular Disorders Research
- Lung Cancer Research Studies
- Heat shock proteins research
- Cancer-related molecular mechanisms research
- Cancer, Hypoxia, and Metabolism
- Cancer Genomics and Diagnostics
- Spine and Intervertebral Disc Pathology
- Lung Cancer Treatments and Mutations
- Osteoarthritis Treatment and Mechanisms
- Radiomics and Machine Learning in Medical Imaging
- Cancer Immunotherapy and Biomarkers
Institute of Hematology & Blood Diseases Hospital
2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2025
Guangdong Provincial People's Hospital
2021-2024
Second Affiliated Hospital of Nanchang University
2024
Nanchang University
2024
First Affiliated Hospital of Jiangxi Medical College
2024
Intervertebral disc degeneration (IDD) is widely regarded as the primary contributor to low back pain(LBP). As an immune-privileged organ, upon onset of IDD, various components nucleus pulposus (NP) are exposed host's immune system, accumulating cytokines. Cytokines facilitate intercellular communication within induce cells polarisation, and exacerbate oxidative stress in IDD.
<title>Abstract</title> Background Osteosarcoma (OS) is a highly aggressive malignancy characterized by poor prognosis. Mitochondrial autophagy (mitophagy) has been implicated in tumor initiation, progression, and response to therapy, highlighting it potential prognostic indicator therapeutic target cancers. Despite this, the precise mechanisms underlying mitophagy osteosarcoma remain enigmatic. This research aims develop mitophagy-associated signature guide strategies prognosis estimations....
Osteosarcoma (OS) is a cancerous tumor, and its development greatly influenced by long non-coding RNA (lncRNA). Endoplasmic reticulum stress (ERS) an essential biological defense process in cells contributes to the progression of tumors. However, exact mechanisms remain elusive. This study aims develop signature lncRNAs associated with ERS OS. will guide prognosis prediction determination appropriate treatment strategies. The UCSC Xena database collected transcriptional clinical data OS...
Background Fever is a common biological phenomenon during the occurrence of infections and tumors in body. However, it unclear whether increase body temperature tumor patients has an impact on immune cells patient prognosis, as well underlying molecular regulatory mechanisms. Its effects patient's disease outcome immunotherapy efficacy are also uncertain. Clarifying mechanism fever will provide new ideas for predicting prognosis formulating strategies. Methods T were cultured at 37.0°C...