A5050799369- Systemic Lupus Erythematosus Research
- Atherosclerosis and Cardiovascular Diseases
- Rheumatoid Arthritis Research and Therapies
- Autoimmune and Inflammatory Disorders Research
- Pharmacological Effects of Natural Compounds
- Systemic Sclerosis and Related Diseases
- Gout, Hyperuricemia, Uric Acid
- Renal Diseases and Glomerulopathies
- Vasculitis and related conditions
- Peripheral Neuropathies and Disorders
- Liver Diseases and Immunity
- Sarcoidosis and Beryllium Toxicity Research
- Orthopedic Surgery and Rehabilitation
- Eosinophilic Esophagitis
- COVID-19 and healthcare impacts
- COVID-19 Clinical Research Studies
- Musculoskeletal synovial abnormalities and treatments
- Otitis Media and Relapsing Polychondritis
- T-cell and B-cell Immunology
- Psoriasis: Treatment and Pathogenesis
- Respiratory viral infections research
- Social Media in Health Education
- Spondyloarthritis Studies and Treatments
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Multiple Sclerosis Research Studies
Universidad San Ignacio de Loyola
2018-2025
Hospital Base Guillermo Almenara Irigoyen
2016-2025
Universidad Científica del Sur
2021-2025
Instituto Nacional de Rehabilitación
2021-2024
University of North Carolina at Chapel Hill
2023
Durham VA Medical Center
2023
Emory University
2023
American College of Rheumatology
2023
Rheumatology Consultants
2023
eLearning Studios (United Kingdom)
2023
<h3>Aim</h3> To determine characteristics associated with more severe outcomes in a global registry of people systemic lupus erythematosus (SLE) and COVID-19. <h3>Methods</h3> People SLE COVID-19 reported the Global Rheumatology Alliance from March 2020 to June 2021 were included. The ordinal outcome was defined as: (1) not hospitalised, (2) hospitalised no oxygenation, (3) any ventilation or oxygenation (4) death. A multivariable logistic regression model constructed assess relationship...
To determine if achieving lupus low disease activity state (LLDAS) or remission prevents damage accrual in a primarily Mestizo population. Patients with SLE from single-centre cohort at least two visits occurring every 6 months were included. The definitions used the following: for remission, 2021 Definition Of Remission In SLE; and LLDAS, Asia Pacific Lupus Collaboration. Damage was ascertained Systemic International Collaborating Clinics/American College of Rheumatology Index (SDI)....
Objectives To determine the association between occurrence of hypertension and damage accrual in patients with systemic lupus erythematosus (SLE). Materials methods From January 2012 to 2020, we evaluated 314 SLE patients, all members Almenara Lupus Cohort. We applied American College Cardiology/American Heart Association (ACC/AHA) guidelines define hypertension, Systemic International Collaborating Clinics/American Rheumatology Damage Index (SDI) organ damage, Erythematosus Disease Activity...
Objectives: To determine the possible predictive value of self-efficacy on fatigue in SLE patients. Methods: patients from a single-center prevalent cohort were included. Self-efficacy was ascertained with five instruments Patient-Reported Outcomes Measurement Information System® (PROMIS®) for Managing Chronic Conditions plus PROMIS general self-efficacy. For instruments, score 50 is average clinical population (people chronic condition), higher score, greater Fatigue Functional Assessment...
PV210 / #497 Poster Topic: AS23 - SLE-Diagnosis, Manifestations, & Outcomes Background/Purpose Frailty, measured with the SLICC-FI, has been reported as a predictor of damage in several cohorts. The aim this study is to evaluate SLICC-FI hospitalization systemic lupus erythematosus (SLE) patients. Methods Patients from single-center prevalent cohort were included. was at baseline. Hospitalizations during first 2 years after baseline visit their number well duration. Univariable and...
Aim A decrease in proteinuria has been considered protective from renal damage lupus nephritis (LN), but a cut-off point yet to be established. The aim of this study was identify the predictors patients with LN and determine best for proteinuria. Methods We included defined clinically or histologically. Possible at time diagnosis were examined: proteinuria, low complement, anti-double-stranded DNA antibodies, red cell casts, creatinine level, hypertension, activity (assessed by Systemic...
Objective The study aims to evaluate the impact of patient-reported disease activity in other outcomes (PROs) systemic lupus erythematosus (SLE) patients. Methods SLE patients from Almenara Lupus Cohort were included, and visits performed every 6 months. Disease was assessed with Foundation America Rapid Evaluation Activity (LFA-REAL) PRO, health-related quality life (HRQoL) LupusQoL, fatigue Functional Assessment Chronic Illness Therapy–Fatigue (FACIT-F), work productivity impairment...
Objective To determine the possible predictive value of self-efficacy on health-related quality life (HRQoL) in patients with SLE. Methods Patients SLE from Almenara Lupus Cohort were included. Self-efficacy was ascertained six domains Patient-Reported Outcomes Measurement Information System (PROMIS) for managing chronic conditions. For PROMIS domains, a score 50 is average clinical population (people condition), higher indicates that respondent has greater self-efficacy. HRQoL physical and...
The identification of risk factors for COVID-19 adverse course in autoimmune rheumatic diseases (ARDs) is the utmost importance when approaching patient management; however, data are scarce relation to Latin American population. objective this study was determine predictors hospitalization patients from an ARD community cohort.A real setting longitudinal (March November 2020) cohort carried out. Potential examined included (1) sociodemographic variables (age, gender, education, tobacco use,...
Background Flares in patients with SLE, regardless of their severity, have been associated damage accrual. However, impact on health-related quality life (HRQoL) has not fully evaluated. In fact, disease activity is only minimally HRQoL. Objective To determine the association between flares and Methods Patients from Almenara Lupus Cohort were included. Visits occurring December 2015 February 2020 defined as an increase SLE Disease Activity Index 2000 (SLEDAI-2K) at least 4 points; severe...
Serum uric acid levels have been reported as predictors of cardiovascular, pulmonary, neurological and renal morbidity in patients with SLE. However, their role cumulative global damage these has not yet determined.To determine whether serum are associated new SLE.This is a longitudinal study SLE from the Almenara Lupus Cohort, which began 2012. At each visit, demographic clinical characteristics were evaluated, such activity (Systemic Erythematosus Disease Activity Index-2K or SLEDAI-2K)...
Systemic lupus erythematosus (SLE) disproportionately affects Latin American and Latino populations, with worse outcomes compared to nonminority populations. Understanding patients' views is critical provide culturally competent care. The objective of this research analyze lived experiences SLE from comments made by patients, their relatives friends, on the public Facebook group "Hablemos de Lupus" (in English: "Let's Talk about Lupus").Deidentified narratives posted as a reaction most...
Objective The aim of this study was to determine whether remission and low disease activity state protect systemic lupus erythematosus patients from being hospitalized. Materials methods Patients the Almenara Lupus Cohort were included. Visits performed every 6 months. Variables measured at each visit. Hospitalizations evaluated in interval between two visits. Remission defined as: a SLEDAI-2 K 0, prednisone ≤5 mg/day immunosuppressants on maintenance dose; ≤4, ≤7.5 dose. Univariable...
The aim of this study was to identify the demographic and clinical features patients with ANCA-associated vasculitides (AAVs) in a Peruvian tertiary referral hospital.Medical records AAV according classification criteria or diagnosed by an experienced rheumatologist, covering period between January 1990 December 2019, were reviewed. Granulomatosis polyangiitis (GPA), microscopic (MPA), eosinophilic granulomatosis (EGPA), renal-limited vasculitis (RLV) included. Demographic factors (age at...
To evaluate the Systemic Lupus International Collaborating Clinics Frailty Index (SLICC-FI) as a predictor of damage accrual in primarily Mestizo SLE patient cohort.Patients from single-center prevalent cohort were included. Damage was defined increase SLICC/American College Rheumatology (ACR) index (SDI) scores between baseline and last visits. The SLICC-FI measured at baseline. Univariable multivariable Cox regression models performed to determine association (per 0.05 increase) SDI,...
Objectives This study aimed to determine the prevalence of ultrasound-detected tendon abnormalities in healthy subjects (HS) across age range. Methods Adult HS (age 18–80 years) were recruited 23 international Outcome Measures Rheumatology ultrasound centres and clinically assessed exclude inflammatory diseases or overt osteoarthritis before undergoing a bilateral examination digit flexors (DFs) 1–5 extensor carpi ulnaris (ECU) tendons detect presence tenosynovial hypertrophy (TSH), power...
<h3>Background:</h3> Improvement in ultrasound technology the last decade results high resolution images. Therefore, previously undetected lesions joints of asymptomatic healthy individuals have now become apparent. At present, cut-off between normal vs abnormal sonographic findings small is unclear. threshold normality that discriminates physiological minimal pathological changes at each joint level different age groups needs to be defined. <h3>Objectives:</h3> The objective this study was...
To determine the association between radiologic joint damage (JD) and a lower lean body mass (LBM) in rheumatoid arthritis (RA) patients.
The aim of this study was to evaluate the response rituximab (RTX) as treatment for lupus nephritis (LN) in a Latin American Lupus cohort.
Objective To determine the reliability of SLE patients' disease activity measurements. Methods This was a cross-sectional study conducted (August 2016–December 2017) at 2 main public Peruvian hospitals, 1 with comprehensive lupus care program. Patients assessed their visual analog scale (VAS) (0–100 mm) or numerical rating (NRS) (0–4) before and after physician's (MD's) assessment. Demographic disease-related characteristics were recorded. Reliability MD's assessment determined using...
Objective The Lupus Foundation of America Rapid Evaluation Activity in (LFA-REAL) clinician-reported outcome (ClinRO) and the LFA-REAL patient-reported (PRO) were developed order to capture manifestations SLE from perspective both clinician patient. aim this study is compare ClinRO PRO with other lupus disease activity measures. Methods A cross-sectional analysis patients a single-centre cohort was performed using Spearman’s correlation. Disease measures included (range 0–1400), 0–1200),...
Introduction: After more than 20 years of sustained work, the Latin American Group for Study Lupus (GLADEL) has made a significant number contributions to field lupus, not only in differential role that race/ethnicity plays its course and outcome but also several other studies including beneficial effects using antimalarials lupus patients development consensus guidelines treatment our region. Methods: A new generation “Lupus Investigators” 40 centers throughout America been constituted...