A5057288683- Environmental Toxicology and Ecotoxicology
- Aquaculture disease management and microbiota
- Aquaculture Nutrition and Growth
- Pharmaceutical and Antibiotic Environmental Impacts
- Animal Ecology and Behavior Studies
- Animal testing and alternatives
- Insect Utilization and Effects
- Wildlife Ecology and Conservation
- Analytical Methods in Pharmaceuticals
- Yersinia bacterium, plague, ectoparasites research
- Regulation of Appetite and Obesity
- Forensic Entomology and Diptera Studies
- Cholesterol and Lipid Metabolism
- Pesticide Exposure and Toxicity
- Ecology and biodiversity studies
- Adipose Tissue and Metabolism
- Rangeland Management and Livestock Ecology
- Electrochemical Analysis and Applications
- Pesticide and Herbicide Environmental Studies
- Gut microbiota and health
- Insect and Pesticide Research
- Microfluidic and Capillary Electrophoresis Applications
- Animal Nutrition and Physiology
- Malaria Research and Control
- Species Distribution and Climate Change
German Environment Agency
2021-2025
University of Tübingen
2018-2020
University of Würzburg
2016
Loma Linda University
2007
Loma Linda University Medical Center
2007
For decades, we have known that chemicals affect human and wildlife behavior. Moreover, due to recent technological computational advances, scientists are now increasingly aware a wide variety of contaminants other environmental stressors adversely organismal behavior subsequent ecological outcomes in terrestrial aquatic ecosystems. There is also groundswell concern regulatory ecotoxicology does not adequately consider behavior, primarily lack standardized toxicity methods. This has, turn,...
Abstract Hunting and trade of wild animals for their meat (bushmeat), especially mammals, is commonplace in tropical forests worldwide. In West Central Africa, bushmeat extraction has increased substantially during recent decades. Currently, such levels hunting pose a major threat to native wildlife. this paper, we compiled published data on offtake from number studies conducted between 1990 2007 Cameroon, African Republic, Democratic Republic Congo, Equatorial Guinea, Gabon, Congo. From...
Due to the rising number of type 2 diabetes patients, antidiabetic drug, metformin is currently among those pharmaceuticals with highest consumption rates worldwide. Via sewage-treatment plants, enters surface waters where it frequently detected in low concentrations (µg/L). Since possible adverse effects this substance aquatic organisms have been insufficiently explored date, aim study was investigate impact on health and development brown trout (Salmo trutta f. fario) its microbiome. Brown...
Exposure of wildlife to anticoagulant rodenticides (ARs) has been extensively documented for species directly or indirectly linked pest rodents via the terrestrial food web. Recently, scientific focus extended a former blind spot, namely AR emissions aquatic environment, and provided clear evidence residues in freshwater fish. As second-generation ARs are likely be transferred along chain, total 122 Eurasian otter (Lutra lutra) individuals found dead Germany between 2005 2021 were...
Widely used second-generation anticoagulant rodenticides like brodifacoum are classified as persistent, bioaccumulative, and toxic. Widespread exposure of terrestrial avian non-target species is well-known recently hepatic rodenticide residues have been detected in wild fish. However, no sufficient data exist to interpret the effects these findings on fish health. In order assess potential impact fish, we exposed rainbow trout (Oncorhynchus mykiss) brodifacoum-spiked feed. a first...
Pharmaceuticals can enter surface waters via sewage treatment plants. In the environment, substances and their transformation products, formed by degradation of parent compounds, may affect aquatic wildlife including freshwater invertebrates. However, research on pharmaceutical-induced effects in feral organisms other than fish is still scarce to date. our study, we therefore investigated impact highly consumed antidiabetic drug metformin its main product guanylurea health a gastropod – big...
In situ exposure of rainbow trout up- and downstream differently equipped wastewater treatment plants (WWTPs) subsequent analyses micronuclei frequencies hepatic EROD activities were used to evaluate the impact effluents on fish health. Two facilities (WWTPs A B) conventional plants. WWTP C has been with a powdered activated carbon stage. Here, conducted prior this upgrade. Differences did not only occur when comparing A, B upgrade) advanced (WWTP after upgrade), but also between...
Abstract Background The anti-diabetic pharmaceutical metformin is frequently analysed in the aquatic environment. Its impact on fish microbiome studied to get a deeper knowledge about consequence of presence river systems. Gut analyses were performed larval brown trout with including environmental concentrations. Therefore, exposed concentrations 0, 1, 10, 100, and 1000 µg/L. Especially, lower measured waters containing percentages conditioned wastewater from municipal treatment plants....
Guanylurea is the main transformation product of antidiabetic drug metformin, which one most prescribed pharmaceuticals worldwide. Due to high rate microbial degradation metformin in sewage treatment plants, guanylurea occurs higher concentrations surface waters than its parent compound and could therefore affect aquatic wildlife. In this context, data for fish are scarce up now made us investigate health brown trout (Salmo trutta f. fario) response guanylurea.In two experiments, eggs plus...
Abstract A method with capillary electrophoresis coupled to mass spectrometry was optimized determine the uptake of metformin and its metabolite guanylurea by zebrafish ( Danio rerio ) embryos brown trout Salmo trutta f. fario exposed under laboratory conditions. Metformin extracted from fish tissues sonication in methanol, resulting an absolute recovery almost 90%. For extraction trout, solid-phase implemented a 84%. The use mixture methanol glacial acetic acid as non-aqueous background...