A5014150080- Intracerebral and Subarachnoid Hemorrhage Research
- Traumatic Brain Injury and Neurovascular Disturbances
- Cerebrospinal fluid and hydrocephalus
- Traumatic Brain Injury Research
- Neurosurgical Procedures and Complications
- Advanced Neuroimaging Techniques and Applications
University of Pecs
2016-2021
Previously, we reported human traumatic brain injury cases demonstrating acute to subacute microbleed appearance changes in susceptibility-weighted imaging (SWI-magnetic resonance [MRI]). This study aims confirm and characterize such temporal alterations an experimental model. To elicit formation, brains of male Sprague Dawley rats were pierced a depth 4 mm, parasagittal position bilaterally using 159 μm 474 needles, without the injection autologous blood or any agent. Rats underwent 4.7 T...
A traumatic brain injury (TBI) induces the formation of cerebral microbleeds (CMBs), which are associated with cognitive impairments, psychiatric disorders, and gait dysfunctions in patients. Elderly people frequently suffer TBIs, especially mild trauma (mTBI). Interestingly, aging is also an independent risk factor for development CMBs. However, how TBI may interact to promote CMBs not well established. In order test hypothesis that mTBI exacerbates elderly, we compared number distribution...
Purpose: A former rodent study showed that cerebral traumatic microbleeds (TMBs) may temporarily become invisible shortly after injury when detected by susceptibility weighted imaging (SWI). The present aims to validate this phenomenon in human SWI. Methods: In retrospective study, 46 brain (TBI) patients various forms of severity were included and willingly complied with our strict selection criteria. Clinical parameters potentially affecting TMB count, Rotterdam Marshall CT score, Mayo...