- Blood Pressure and Hypertension Studies
- COVID-19 Clinical Research Studies
- Cardiovascular Health and Disease Prevention
- Long-Term Effects of COVID-19
- Neurological Disorders and Treatments
- Diabetes Treatment and Management
- Metabolism, Diabetes, and Cancer
- Cytokine Signaling Pathways and Interactions
- Metabolism and Genetic Disorders
- Yersinia bacterium, plague, ectoparasites research
- Vibrio bacteria research studies
- Chemotherapy-induced cardiotoxicity and mitigation
- S100 Proteins and Annexins
- Liver Disease Diagnosis and Treatment
- Acute Myocardial Infarction Research
- Cardiovascular Disease and Adiposity
- Cardiac Fibrosis and Remodeling
- Viral Infections and Immunology Research
- Neurological and metabolic disorders
- Drug-Induced Hepatotoxicity and Protection
- Biomarkers in Disease Mechanisms
- Radiopharmaceutical Chemistry and Applications
- Climate Change and Health Impacts
- Intracerebral and Subarachnoid Hemorrhage Research
- Pancreatitis Pathology and Treatment
Irkutsk State Medical University
2021-2023
Background. One of the most common arrhythmias in clinical practice is atrial fibrillation. Restoration sinus rhythm preferable for this type arrhythmia. Radiofrequency ablation improves prognosis and quality life patient. Simultaneous coronary revascularization persistent fibrillation allows achieving expected result. However, simultaneous performance these operations can increase risk postoperative complications, including recurrence Outpatient management such patients difficult, since...
Description of a clinical case. The article presents observation 77-year-old patient with newly diag-nosed Frederick’s syndrome, which is combination permanent form atrial fibrillation and complete atrioven-tricular block. An exacerbation chronic pancreatitis was the reason for hospitalization patient. had no complaints bradycardia or syncope, but treatment underlying disease difficult due to development acute kidney injury against background uncompensated heart failure. cause syndrome...
Background. Creatine phosphokinase is an enzyme that often associated with muscle and myocardial disorders. However, other causes of elevated level this are possible, such as stroke, hypothyroidism, paraneoplastic syndrome, well various pharmacological effects, including taking statins the development statin-associated symptoms, consequences a previous coronavirus infection COVID-19. The aim work. To determine cause increased creatine in patient after concomitant diseases; to carry out...
Введение. Повышенное артериальное давление и дислипидемия являются важнейшими модифицируемыми факторами сердечно-сосудистого риска, коррекция которых может внести существенный вклад в снижение заболеваемости смертности. Эти взаимосвязанные состояния ускоряют изменения свойств сосудистой стенки, то есть способствуют «сосудистому старению». Для оценки риска принято использовать шкалы. В России Европе применяют шкалу SCORE, отражающую 10-летний риск фатальных сердечно-сосудистых осложнений,...
Background . Production of pro-inflammatory cytokines including interleukin 6 (IL-6) is activated in COVID-19. Using olokizumab which inhibits IL-6 production treatment COVID-19 pathogenetically justified. The aim To study real clinical practice the efficacy and safety using IL-6inhibitor (olokizumab) patients with confirmed pneumonia. Materials methods first group included 41 hospitalized pneumonia having complex therapy olokizumab. control consisted 66 who did not have inhibitor. We...
The aim of the study was to estimate a level thyrotropin-receptor antibodies (TRAb), some cytokines (TNF-α, IL-8, IL-10) in Graves' disease patients with chronic heart failure (CHF) and reveal prognostic factors CHF.89 were investigated, diagnosed 46 (51.7%) cases, from them 1 stage – 27 (58.7%) patients, 2А 17 (37.0%) 2b 2 (4.3%) patients. However, tachycardia, dyspnea other symptoms at СHF stages could be eхplained by CHF as well disease, therefore firs group composed 19 (21.3%) 2b. Second...
The article presents a clinical case of the fatal Mallory- Weiss syndrome, which suddenly developed in an 86-year-old patient with new coronavirus infection COVID-19, complicated by bilateral polysegmental pneumonia. had no history gastroesophageal refl ux disease, gastric ulcer or duodenal ulcer. level D-dimer on admission was elevated, but prescribed reduced dose anticoagulants (heparin). Despite initial positive dynamics condition, wave-like course followed development extremely severe...
Aim. Assessment of vascular age by volumetric sphygmography and its relationship with the main clinical laboratory parameters in patients arterial hypertension. Materials methods. 46 hypertension were examined, including 26 women (56.5%) 20 men (43.5%). The mean was 67.0 [60.0; 73.5] years. Clinical analyzed, body mass index, lipidogram, fibrinogen, blood creatinine levels, glomerular filtration rate. Vascular assessed using BPLab-Vasotens apparatus (LLC Petr Telegin, Russia). Results. 69.0...
Введение. Артериальная гипертензия (АГ) является одним из наиболее распространенных сердечно-сосудистых заболеваний (ССЗ) и оказывает существенное влияние на смертность населения. По данным наблюдательного исследования ЭССЕ-РФ-2, заболеваемость АГ составляет более 40 % имеет неуклонную тенденцию к росту [1]. Повышенное артериальное давление (АД), как дислипидемия, являются важными и, что очень существенно, модифицируемыми факторами риска катастроф. Наличие одного состояния может...
Dietary supplements are often self-administered by patients for weight loss. However, the hepatotoxicity of such remains underestimated. Liver damage is diverse: from asymptomatic reversible course to lethal fulminant hepatitis. In case a long unrecognized and prolonged use dietary supplements, irreversible structural functional organ occurs. We present retrospective analysis histories patient with liver cirrhosis, who has history using Thai Chinese origin, hellebore extract, during 5 years...
Introduction: The term "vascular age" (VA) was developed to motivate and increase patients' commitment a healthy lifestyle. This assessment can significantly help in communication between the doctor patient. CO is age of person who has same probability death from cardiovascular diseases as patient, only without modifiable risk factors. CV be determined using instrumental methods or calculated modified SCORE scale, latter method currently limited due modification SCORE2 SCORE-OP scales. aim...
Background. The most common thyroid disease, accompanied by thyrotoxicosis syndrome, is Graves' disease (GD). Information about the role of Yersinia in development this contradictory. Aims. To study significance (Y.) enterocolitica and Y. pseudotuberculosis disease. Materials methods. 78 patients with GD. Identification antibodies to was carried out following methods: 1. agglutination test (AT) suspensions live virulent cultures pseudotuberculosis, O:3 O:9; 2. indirect...
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