A5006239983- Healthcare Systems and Public Health
- Human Health and Disease
- Neurological Disorders and Treatments
- Rheumatoid Arthritis Research and Therapies
- Gout, Hyperuricemia, Uric Acid
- Systemic Lupus Erythematosus Research
- Viral Infections and Immunology Research
- Biomarkers in Disease Mechanisms
- Systemic Sclerosis and Related Diseases
- Cardiovascular Function and Risk Factors
- Thyroid Disorders and Treatments
- Cardiac Imaging and Diagnostics
- Cardiovascular Disease and Adiposity
- Urological Disorders and Treatments
- Linguistics and language evolution
- Radiopharmaceutical Chemistry and Applications
- Acute Myocardial Infarction Research
- Medical and Biological Sciences
- Heart Failure Treatment and Management
- Bone health and treatments
- Medical Imaging Techniques and Applications
- Cardiac pacing and defibrillation studies
- Heterotopic Ossification and Related Conditions
- Pericarditis and Cardiac Tamponade
- Global Public Health Policies and Epidemiology
Irkutsk State Medical University
2015-2025
Ministry of Health of the Russian Federation
2017-2025
City Clinical Hospital
2018-2025
Kerala Institute of Medical Sciences
2014
Highlights The frequency of Dressler syndrome decreased sharply from 20 to less than 5% with the introduction early reperfusion into clinical practice. Relapses Dressler’s post-infarction are quite common. review presents current literature data on etiology and pathogenesis, diagnostic methods various approaches treatment syndrome, including effectiveness colchicine reports use immunoglobulins. Annotation development relapses within 1 year after first occurrence event, despite decrease in...
Objective of the Review: To consider pathogenetic relationship COVID-19 and chronic heart failure, concept “postcovid syndrome”, peculiarities management this group patients. Key points. Chronic failure is a predictor an unfavorable outcome in patients with COVID-19. Angiotensin converting enzyme 2 involved penetration viral particles into cell. Direct damage to cardiomyocytes not excluded, cardiotoxic effects antiviral therapy are possible. The consequences manifested by arrhythmia,...
Aim . Switching to another biologic with the same mode of action provides greater opportunity for long-term management patients rheumatoid arthritis (RA). In clinical practice, especially in context COVID-19 pandemic, such switching occurred non-medical reasons as well. However, there is no information about from interleukin 6 (IL-6) receptor (R) inhibitor direct IL-6 inhibitor. Objective – assess efficacy and safety therapy RA patients, after IL-6R inhibitors (tocilizumab (TOC), sarilumab...
Abstract Background There are several approaches to the surgical treatment of penile curvature conditionally divided into three large groups: tunica albuginea plication (TAP), corpus cavernosum rotation (CR), and transplantation various materials. The study aims compare effectiveness TAP CR techniques in curvature. was a prospective randomized patients with an established diagnosis from 2017 2020 Irkutsk, Russian Federation. final analysis results included 22 cases. Results comparative...
There are limited studies on heart failure in Indian population OBJECTIVE: Present study aimed to assess the in-hospital 90-day and two year outcomes patients with ischemic (IHD-HF) non (NIHD-HF).Patients NYHA Class III & IV, who were admitted our intensive care unit (HF), evaluated followed up for 2years.In cohort of 287 patients, there 192 (66.9%) males 95 (33.1%) females. Patients divided into IHD-HF 180 (62.7%) NIHD-HF 107 (37.3%) patients. Mean age group was 66 (+/-10) 61 (+/-11)....
Neuropathic pain is an acute or chronic caused by damage to dysfunction of the peripheral and/or central nervous system. a direct sequel disease somatosensory The paper presents definition, international diagnostic criteria, clinical and features, causes neuropathic syndrome, differences between nociceptive pain, classification major syndromes, DN4 questionnaire identify pain. It shows substantial pathophysiological similarity fibromyalgia gives preliminary criteria for fibromyalgia....
Изложены данные об истории описания остеопетроза («мраморной» болезни), его клинических особенностях, диагностике и возможных подходах к терапии. Представлено собственное клиническое наблюдение.
Urethral stricture is a partial or complete narrowing of the urethra, caused by damage to urethral epithelium. This disease leads persistent urination dysfunction, elimination which difficult task. The aim this study was perform comparative analysis immediate and long-term treatment results proximal part bulbar membranous parts using developed magnifying anastomotic methods.A total 102 patients with confirmed diagnosis bulbomembranous urethra who underwent in urological hospital Irkutsk City...
Objective: to study the rate of metabolic syndrome (MS) and its components among gout patients in different regions Russian Federation. Subjects methods. This cross-sectional multicenter enrolled 2277 patients, including 1963 (86.2%) men 314 (13.8%) women, from 12 independent medical centers The over 18 years age who met classification criteria for gout, elaborated by S. Wallace et al., were included. diagnosis MS was established on basis Adult Treatment Panel III (ATP III) criteria....
Objective. Primary hyperaldosteronism (PGA) (Conn’s syndrome) is a relatively rare phenomenon in therapeutic practice, occurring 4,7–9%. In resistant hypertension (HTN) the rate of PGA achieves 10–20%. Often it results from aldosterone-producing adrenal tumors and manifests by symptomatic HTN, neuromuscular, renal symptoms. We present cases successful verification surgical treatment PGA. HTN patients with rhabdomyolysis symptoms (increased creatine phosphokinase or lactate dehydrogenase)...
Objective: to evaluate the safety and efficacy of first Russian botulinum toxin-A relatox versus botox in treating arm hand spasticity after ischemic stroke. Patients methods. A multicenter randomized clinical trial was conducted 6 centers Federation, which covered 160 patients with prior stroke upper limb spasticity (an Ashworth scale score at least 2). Not earlier than 3 months after stroke, a single injection of or made, followed by evaluation changes muscle tone presence severity adverse...
The purpose of this work is to attempt provide an overview current recommendations for the diagnosis and treatment familial Mediterranean fever, as well present our own clinical observation pathology. A selective analysis literature over past 5 years (2020-2024) was carried out in scientometric databases PubMed (https://pubmed.ncbi.nlm.nih.gov) Russian Science Citation Index (www.elibrary.ru). Current data on autoinflammatory disease fever are reviewed. It important understand fact that...
Objective : to investigate the efficacy and safety of olokizumab (OKZ) in patients with rheumatoid arthritis (RA) over a 12-month period after switching from interleukin (IL)-6 receptor inhibitors (iIL6R) for non-medical reasons. Material methods . A retrospective cohort study conducted 11 centers Russian Federation included 110 confirmed diagnosis RA according 2010 ACR/EULAR criteria. In all early 2022 (due problems drug supply during coronavirus pandemic) iIL6R were switched reasons OKZ at...
Aim. To consider modern views on risk factors and progression of chronic heart failure (CHF), the main causes hyperammonemia, clinical pathogenetic relationship hyperammonemia CHF approaches to patient management. Key points. is one leading cardiovascular problems today. The prevalence varies from 0.3% in people aged 20–29 years 70% over 90 old. In case progressive HF, it may be necessary have a transplant or long-term mechanical circulatory support, as well palliative care, which also...
Objective: demonstrate clinical observation of a patient suffering from infectious myocarditis, discuss the general principles diagnosis and treatment. Methods. The analysis case histories outpatient records who underwent myocardial infarction in dynamics was carried out. Laboratory instrumental research methods were studied. Results. final M made based on following diagnostic criteria: relationship with previous viral infection anamnesis, an increase heart failure, confirmed by high proBNP...
Aim . To study the relationship of systemic inflammation with morphological and functional myocardial parameters in patients heart failure (HF) due to hypertension coronary artery disease combination rheumatoid arthritis (RA). Material methods The included 57 women NYHA class I-II HF. Patients were divided into two comparable groups: group 1 (n=31) — HF seropositive RA (Steinbrocker X-ray stage I-III); 2 (n=26) without RA. Results A comparative analysis did not reveal significant...
Currently, type 2 myocardial infarction is a rather significant problem, both in terms of diagnosis and treatment. Myocardial without obstructive coronary artery damage occurs 5-10 % patients with infarction. Optimal strategies for the treatment associated non-thrombotic mechanisms have not yet been determined. The article describes clinical observation on background vasospasm, as well diagnostic therapeutic tactics this situation. main provisions: patient was 22 years old cardiology...
В статье представлены современные данные об урогенных реактивных артритах, которые будут полезны практическим врачам в процессе работы с больными, страдающими суставной патологией.
Background . Production of pro-inflammatory cytokines including interleukin 6 (IL-6) is activated in COVID-19. Using olokizumab which inhibits IL-6 production treatment COVID-19 pathogenetically justified. The aim To study real clinical practice the efficacy and safety using IL-6inhibitor (olokizumab) patients with confirmed pneumonia. Materials methods first group included 41 hospitalized pneumonia having complex therapy olokizumab. control consisted 66 who did not have inhibitor. We...
This review presents relevant information about development and course of chronic heart failure (CHF) associated with rheumatoid arthritis (RA). One the most discussed issues is effect systemic inflammatory process on prognosis CHF. The focused current evidence for significance this comorbidity in diagnostic role immune markers, such as galectin 3, pentraxin growth differentiation factor 15, osteopontin was described. antiinflammatory therapy CHF presence diseases. Possible beneficial...
Background: The prevalence of varicose veins small pelvic in women reproductive age varies widely – from 5.4 to 80 %, due the low specificity and sensitivity clinical diagnostic techniques, absence biomarkers that can be used identify formation progression women. Aims: To changes levels parameters system “lipid peroxidation antioxidant protection” with development pelvis women, as well possibility their use. Materials methods: We examined 200 signs pelvis. Control group included 30 without...
There are several options for vessel-sparing anastomotic procedures that allow one to avoid disturbances in the normal blood supply spongy body and successfully perform plastic surgery of distal urethral strictures.To a comparative analysis effectiveness reconstructive surgical treatment strictures bulbo-membranous urethra with without vessel-sparing.A prospective study was carried out on 28 patients diagnosis stricture who underwent period 2012-2018 conditions urological hospital Irkutsk...
Aim To study features of coronary damage and incidence different types acute syndrome (ACS) in history associated with primary symptomatic hypothyroidism patients ischemic heart disease (IHD) possible associations replacement hormonal therapy lipidogram indexes.Material methods This retrospective included 344 IHD functional class I-III stable angina (ССS, 1976). Of them 100 had 244 no hypothyroidism. Coronary angiography was performed for all into this study. Routine laboratory, instrumental...