- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Blood Coagulation and Thrombosis Mechanisms
- Nonmelanoma Skin Cancer Studies
- Maternal and fetal healthcare
- Polyomavirus and related diseases
- Pregnancy and preeclampsia studies
- Cutaneous Melanoma Detection and Management
- Neonatal Respiratory Health Research
- Maternal and Perinatal Health Interventions
- Head and Neck Cancer Studies
- Skin Protection and Aging
- Cardiac, Anesthesia and Surgical Outcomes
- Cancer and Skin Lesions
- Hospital Admissions and Outcomes
- Ectopic Pregnancy Diagnosis and Management
- Pneumocystis jirovecii pneumonia detection and treatment
- Neonatal and Maternal Infections
- Breastfeeding Practices and Influences
- Cytomegalovirus and herpesvirus research
- Growth Hormone and Insulin-like Growth Factors
- Bladder and Urothelial Cancer Treatments
- Surgical site infection prevention
- Cutaneous lymphoproliferative disorders research
- Clinical Nutrition and Gastroenterology
- Infant Nutrition and Health
QIMR Berghofer Medical Research Institute
2016-2022
Royal Brisbane and Women's Hospital
2018-2021
Southampton General Hospital
2002
Urinary tract infections (UTI) are the most common of after renal transplantation. The consequences UTIs in this population serious, with increased morbidity and hospitalisation rates as well acute allograft dysfunction. may impair overall graft patient survival. We aimed to identify prevalence risk factors for post-transplant assess UTIs' effect on function during a UTI episode if they result declining at 2 years post-transplant. Additionally, causative organism, class antibacterial drug...
Abstract Introduction Hyperbaric oxygen therapy ( HBOT ) is widely used for the treatment of late effects radiation therapy. We report a prospective observational cohort study 51 patients designed to examine effectiveness hyperbaric xerostomia following radiotherapy. Methods Objective (saliva volume) and subjective (quality life scoring visual analogue scale VAS discomfort) measurements associated with were compared prior commencement , after 30 sessions (over 6 weeks) at 243 kP 90 minutes...
Lung transplant recipients are at high risk of skin cancer, but precise annual incidence rates treated cancers per patient unknown.To perform a prospective assessment the total burden histologically confirmed squamous cell carcinoma (SCC) and basal (BCC) associated factors in lung recipients.A population-based cohort 125 Queensland aged 18 years over, recruited between 2013 2015, were followed to end 2016. All underwent dermatological examinations baseline annually thereafter patients...
The aim of this study was to establish rotational thromboelastometry (ROTEM® ) baseline parameters in labouring women at term gestation. secondary compare these reference ranges with those from previous studies on and the manufacturer.A prospective, observational study.Tertiary referral hospital.Healthy labour.Ethics approval granted for an opt-out recruitment approach. ROTEM® testing performed Women any condition affecting coagulation were excluded. Delta derived by calculating 2.5% 97.5%...
A voluntary, anonymous, cross-sectional online survey was conducted among 997 Fellows of the Australian and New Zealand College Anaesthetists, using an electronic questionnaire. Details about their demographics, employment, research experience barriers they had encountered, perception future intentions to participate in research, were collected. The response rate 24.6%. At time survey, 29% respondents involved research. Respondents currently more likely be practising at a tertiary hospital,...
Abstract Background The purpose of this study was to determine if p16 status, chemotherapy regimen, or other nutrition markers could improve protocol accuracy in predicting proactive gastrostomy patients with head and neck cancer. Methods Patients who received curative treatment from July 2010 June 2011 were included ( n = 269). Associations among dependent variables (age, sex, tumor site, staging, treatment, albumin, Malnutrition Screening Tool [MST] score), the risk rating, requirement for...
Rotational thromboelastometry (ROTEM® ) is a point-of-care coagulation test which has been used to demonstrate hypercoagulability in pregnant populations and obese populations.The aim of this study was assess the combined effect pregnancy obesity on using ROTEM® healthy women varying body mass indices (BMIs) presenting for elective caesarean delivery.Ethics approval granted recruitment delivery. Women with any condition affecting were excluded. The parameters extrinsically activated...
Aim To determine the rate, type and timing of bacterial endotracheal tube (ETT) colonisation in neonates born <32 weeks gestational age (GA); if is associated with chronic lung disease (CLD), septicaemia, length‐of‐stay or mortality. Methods All intubated newborns GA were included. Endotracheal aspirates routinely obtained three times‐per‐week. Cohort was divided into groups: no growth, normal respiratory flora only, significant bacteria. Logistic regression performed to identify ETT CLD,...
As a result of increasing longevity, we are seeing more elderly patients with complex medical co-morbidities who sustain hip fractures requiring surgical management. The aim this study is to understand and analyze the effect preoperative comorbidities associated low physiological reserve status on functional rehabilitation outcomes following management fractures.This conducted retrospective analysis 73 fulfilled inclusion criteria .We utilized de Morton Mobility Index (DEMMI) scores pre...
Central nervous system oxygen toxicity (CNS-OT) is an uncommon complication of hyperbaric treatment (HBOT). Different facilities have developed local protocols in attempt to reduce the risk CNS-OT. This audit was performed elucidate which might be benefit mitigating CNS-OT and open discussion on adopting a common protocol for Treatment Table 14 (TT14) enable future multicentre clinical trials.Audit events between units using different compression profiles TT14, at 243 kPa with variable...
Organ transplant recipients (OTRs) are at greater risk of basal cell carcinomas (BCCs) than non-OTRs, but histopathologic differences between BCCs in OTRs and the general population largely unknown. We compared clinicopathologic features vs Queensland, Australia. Details BCC tumors (site, size, level invasion, subtype, biopsy procedure) were collected from histopathology reports two prospective skin cancer studies, one general-population-based. used log-binomial regression models to estimate...
Abstract Background Neutropenic fever is a frequently encountered complication when caring for cancer patients and can lead to intensive care admission, with high mortality rates in those who require invasive mechanical ventilation (IMV). Although hospital survival this population has improved, long‐term outcomes of critically ill neutropenic have not been well defined. Aims To evaluate short‐ admitted care, according requirement ventilation. Additionally, we aimed determine predictors poor...
Rotational thromboelastometry (ROTEM® ) is a point-of-care test of coagulation. ROTEM® -defined hypercoagulability has been identified in pregnant women and non-pregnant patients with diabetes mellitus. Pregnancy known to be hypercoagulable state, but the influence gestational mellitus (GDM) on coagulation unknown.The aim this study was assess combined effect pregnancy GDM using compare healthy presenting for elective caesarean delivery.Ethics approval granted recruitment delivery. Women...
Various treatments of keratotic skin lesions and early cancers are performed in organ transplant recipients (OTRs) at high risk malignancies but the frequency their use is unknown. We prospectively assessed cryotherapy, diathermy, topical therapies also investigated associations with background incidence histologically-confirmed squamous-cell carcinoma (SCC) basal cell (BCC) a cohort OTRs Queensland, Australia. Median follow-up ranged from 1.7 to 3.2 years across groups. Among 285 kidney,...