Mohammad Hosein Afsarian

ORCID: 0000-0003-3444-9319
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About
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Research Areas
  • Antifungal resistance and susceptibility
  • Fungal Infections and Studies
  • Plant Pathogens and Fungal Diseases
  • Nail Diseases and Treatments
  • Yeasts and Rust Fungi Studies
  • Synthesis and biological activity
  • Dermatology and Skin Diseases
  • Psoriasis: Treatment and Pathogenesis
  • Asthma and respiratory diseases
  • Infective Endocarditis Diagnosis and Management
  • Essential Oils and Antimicrobial Activity
  • Synthesis of Tetrazole Derivatives
  • Bacterial Identification and Susceptibility Testing
  • Streptococcal Infections and Treatments
  • Computational Drug Discovery Methods
  • Phytochemical compounds biological activities
  • Infectious Diseases and Mycology
  • Antibiotic Resistance in Bacteria
  • Reproductive tract infections research
  • Fungal Plant Pathogen Control
  • Helminth infection and control
  • Pneumonia and Respiratory Infections
  • Aquaculture disease management and microbiota
  • Fermentation and Sensory Analysis
  • Medicinal Plants and Neuroprotection

Fasa University of Medical Sciences
2014-2024

Mazandaran University of Medical Sciences
2014-2015

Shiraz University of Medical Sciences
2011

Osteoarthritis (OA) is the most common type of arthritis and proinflammatory cytokines have been considered as main etiologic factor in pathogenesis disease. Serum levels cytokines, that are associated with innate immunity TH1 cells, analyzed OA patients, however, there limited research profiles Th17 cells their relation to vitamin D3 pain.The sera from 131 patients 262 healthy controls were evaluated for serum IL-17A, IL-21, IL-23 using ELISA.Serum statistically higher than controls, while...

10.1371/journal.pone.0164757 article EN cc-by PLoS ONE 2016-11-07

Burn intensive care unit (BICU) patients are specifically exposed to deep-seated nosocomial infections due Candida albicans. Superficial carriage of C. albicans is a potential source infection and dissemination, typing methods could be useful trace the different isolates. Multilocus sequence powerful genotyping method for pathogenic micro-organisms, including Thirty clinical isolates obtained from 22 that were admitted BICU burn hospital at Sari, Mazandaran state, Iran, studied...

10.1099/jmm.0.000015 article EN Journal of Medical Microbiology 2015-01-17

A facile and simple protocol for the [3+2] cycloaddition of alkyl nitriles (RCN) with sodium azide (NaN 3 ) in presence copper bis(diacetylcurcumin) 1,2-diaminobenzene Schiff base complex, SiO 2 -[Cu-BDACDABSBC] as a heterogeneous catalyst ascorbic acid solution water/ i -PrOH (50:50, V/V) media at reflux condition is described. The supported was prepared by immobilization complex [Cu-BDACDABSBC] on silica gel. has high selectivity, catalytic activity, recyclability. significant features...

10.17344/acsi.2019.4992 article EN cc-by Acta chimica slovenica 2019-12-18

Candidaalbicans is the most common causative agent of candidiasis. Candidiasis management dependent on immune status host, severity disease, and choice antifungal drug. Antifungals, specifically triazoles, are widely administered for treatment invasive fungal infections. Herein, we aimed to evaluate invitro susceptibility C.albicans isolates fluconazole (FLZ), itraconazole (ITZ), voriconazole (VRZ), amphotericin B (AMB), Caspofungin (CAS).A total 44 clinical strains were collected from 36...

10.18869/acadpub.cmm.2.2.8 article EN cc-by Current Medical Mycology 2016-06-01

Candida glabrata is a pathogenic yeast with several unique biological features and associated an increased incidence rate of candidiasis. It exhibits great degree variation in its pathogenicity antifungal susceptibility.The aim the present study was to evaluate vitro susceptibilities following six drugs against clinical C. strains: amphotericin B (AmB), ketoconazole (KTZ), fluconazole (FCZ), itraconazole (ITZ), voriconazole (VCZ), caspofungin (CASP).Forty strains were investigated using DNA...

10.5812/jjm.36638 article EN Jundishapur Journal of Microbiology 2016-04-23

Incidence of fungal infections caused by opportunistic pathogens, such as yeasts and yeast-like species, has undergone an increase in otherwise healthy individuals. These pathogens account for high mortality show reduced susceptibility to the routine antifungal drugs. Accordingly, testing is urgent need determination spectrum antifungals selection appropriate agents management patients with infection.The present study was conducted on 110 yeast strains belonging 15 species recovered from...

10.18502/cmm.5.4.1949 article EN cc-by Current Medical Mycology 2019-12-04

Abstract Background Trichosporonosis is an emerging fungal infection caused by Trichosporon species, a genus of yeast‐like fungi, which are frequently encountered in human infections ranging from mild cutaneous lesions to fungemia immunocompromised patients. The incidence trichosporonosis has increased recent years, owing higher numbers individuals at risk for this infection. Although amphotericin B, posaconazole and isavuconazole generally effective against some isolates may have variable...

10.1111/myc.13306 article EN Mycoses 2021-05-17

Fungal prosthetic valve endocarditis (PVE) is rare but serious complication of replacement surgery. Candida species, particularly albicans the most common isolated pathogen in fungal PVE (1-6%of cases).We describe a 35-year-old woman who underwent mechanical mitral about 3 years ago. She was admitted with neurological symptoms and later dyspnea hypotension. Transesophageal echocardiography showed large mobile vegetation. The explanted vegetation revealed lots budding yeasts yeast identified...

10.5812/jjm.9428 article EN cc-by-nc Jundishapur Journal of Microbiology 2014-03-01

Vulvovaginal candidiasis (VVC) is an opportunistic infection due to Candida species, one of the most common genital tract diseases among reproductive-age women. The present study aimed investigate prevalence VVC non-pregnant women and identify epidemiology involved species with evaluation antifungal susceptibilities.Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) was performed isolated from 350 Moreover, susceptibility testing according Clinical...

10.18502/cmm.7.4.8405 article EN cc-by Current Medical Mycology 2022-01-18

Purpose.Epidermophyton floccosum is an anthropophilic dermatophyte species, which one of the common causative agents dermatophytosis in different parts world. The aim present investigation was to evaluate genetic diversity E. strains isolated from Iran and define vitro susceptibility profiles seven antifungal drugs against these clinical isolates.Methodology. Forty 40 patients with were subjected DNA extraction PCR amplification ITS rDNA region using universal primers ITS1 ITS4. activities...

10.1099/jmm.0.001074 article EN Journal of Medical Microbiology 2019-10-01

Background: The incidence of fungal infections caused by the yeasts and yeast-like species increased dramatically in immunocompromised patients, during past several decades. However, a few yeast may colonize skin mucous membranes healthy individuals. Objectives: current study aimed at accurately identifying from clinical samples molecular methods. Methods: A total 1200 were collected patients with suspected infection 110 (9.16 %) strains isolated identified polymerase chain...

10.5812/jjm.66240 article EN Jundishapur Journal of Microbiology 2018-09-22

Background: Onychomycosis is one of the most common fungal infections. The etiological agents onychomycosis in Iran are Candida species, especially fingernails. It more women than men, particularly workers occupations requiring them to submerge their hands or feet water for prolonged periods. Objectives: current study's main aim was determine abundance candidal onychomycosis, identify species using molecular methods, and evaluate vitro antifungal susceptibility profiles. Methods: One hundred...

10.5812/jjm-139906 article EN Jundishapur Journal of Microbiology 2023-10-25
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