A5014725547- Various Chemistry Research Topics
- Nitric Oxide and Endothelin Effects
- Innovative Teaching Methods
- Analytical Chemistry and Sensors
- Analytical Chemistry and Chromatography
- Experimental Learning in Engineering
- Thermal Regulation in Medicine
- Electron Spin Resonance Studies
- Sulfur Compounds in Biology
- Advanced Chemical Sensor Technologies
- Electrochemical sensors and biosensors
- Educational Strategies and Epistemologies
- Biochemical Analysis and Sensing Techniques
- Material Properties and Processing
- Immune Response and Inflammation
- Science Education and Pedagogy
- biodegradable polymer synthesis and properties
- Sulfur-Based Synthesis Techniques
- Animal Nutrition and Physiology
- Adipose Tissue and Metabolism
- Biopolymer Synthesis and Applications
- Non-Invasive Vital Sign Monitoring
- Receptor Mechanisms and Signaling
- S100 Proteins and Annexins
- Microplastics and Plastic Pollution
College of New Jersey
2020-2022
University of North Carolina at Chapel Hill
2013-2018
Citadel
2018
Ministère de l'Agriculture et de la Souveraineté alimentaire
1982
Ministry of Agriculture Livestock and Fisheries
1982
Nitric oxide (NO), a reactive free radical, has proven effective in eradicating bacterial biofilms with reduced risk of fostering antibacterial resistance. Herein, we evaluated the efficacy NO-releasing silica nanoparticles against Gram-negative Pseudomonas aeruginosa and Gram-positive Staphylococcus aureus as function particle size shape. Three sizes (i.e., 14, 50, 150 nm) identical total NO release (∼0.3 μmol/mg) were utilized to study antibiofilm eradication size. To observe role shape on...
Despite growing reports on the biological action of nitric oxide (NO) as a function NO payload, validity such work is often questionable due to manner in which measured and/or solution composition quantified. To highlight importance measurement technique for given sample type, produced from small-molecule donor (N-diazeniumdiolated l-proline, PROLI/NO) and NO-releasing xerogel film were quantified number physiological buffers fluids, cell culture media, bacterial broth by Griess assay,...
Standard photolithographic techniques and a nitric oxide (NO) selective xerogel polymer were utilized to fabricate an amperometric NO microfluidic sensor with low background noise the ability analyze levels in small sample volumes (~250 μL). The exhibited excellent analytical performance phosphate buffered saline, including sensitivity of 1.4 pA nM(-1), limit detection (LOD) 840 pM, selectivity over nitrite, ascorbic acid, acetaminophen, uric hydrogen sulfide, ammonium, ammonia, both...
A 530 nm light emitting diode was coupled to a microfluidic sensor facilitate photolysis of nitrosothiols (i.e., S-nitrosoglutathione, S-nitrosocysteine, and S-nitrosoalbumin) amperometric detection the resulting nitric oxide (NO). This configuration allowed for maximum sensitivity versatility, while limiting potential interference from nitrate decomposition caused by ultraviolet light. Compared similar measurements total S-nitrosothiol content in bulk solution, use platform permitted...
Students develop process skills through repeated practice of data interpretation, problem solving, and critical thinking. The primary literature provides a rich source application problems to engage students in this within the context chemistry content knowledge. However, most existing classroom activities based on involve reading full articles. To offer more frequent practice, we suggest that instructors prepare assignments excerpted from Herein, demonstrate pedagogical goals, design...
Abstract Bacterial pneumonia is a leading cause of death late after burn injury due to the severe immune dysfunction that follows this traumatic injury. The Mechanistic/Mammalian Target Rapamycin (mTOR) pathway drives many effector functions innate cells required for bacterial clearance. Studies have demonstrated alterations in multiple cellular processes patients and animal models following which mTOR central component. Goals study were (1) investigate importance signaling antimicrobial...
High-performance liquid chromatography is one of the primary techniques covered in undergraduate analytical chemistry curriculum. This technology report describes use a portable capillary-scale instrument that can provide similar performance to benchtop but generates less solvent waste and enables operation nonlaboratory settings. Comparisons between two types were made for single-standard calibration analysis caffeine diet soda aspirin content over-the-counter tablets, with relative percent...
The College of New Jersey's Chemistry Department and School Science have been strategically transforming our teaching, learning, mentoring environments for over a decade through programs that are targeted toward "new majority" students: low-income, first generation, historically marginalized races ethnicities. Recently, we shifted from target small number students to focus on systemic structural changes create inclusive excellence. We formalized work in Theory Change (ToC) emphasizes...
Much of analytical chemistry involves the analysis complex mixtures, where careful attention to sample preparation and method selectivity is required avoid interferents obtain accurate data. As this type very different from simple colorimetric that most students are exposed in general chemistry, laboratory exercise was developed help discover importance preparation, specifically extraction pH adjustment, for quantifying "bitterness" derived iso-α-acid content beer. In exercise, deviate...
An important objective of any analytical chemistry course is for students to generate and interpret data from the analysis complex, real-world samples in order assess effectiveness method, including calibration. In this laboratory exercise, directly compare calibration methods (external standards standard addition, both with without an internal standard) determination ethanol beer using affordable benchtop gas chromatograph. The experiment allows evaluate advantages disadvantages each method...