A5024101094- Tuberculosis Research and Epidemiology
- Antibiotic Resistance in Bacteria
- Antibiotic Use and Resistance
- Mycobacterium research and diagnosis
- Pneumonia and Respiratory Infections
- Nosocomial Infections in ICU
- Diagnosis and treatment of tuberculosis
- Antimicrobial Resistance in Staphylococcus
- Bacterial biofilms and quorum sensing
- Parasites and Host Interactions
- Fungal Infections and Studies
- Infectious Diseases and Mycology
- Vibrio bacteria research studies
- Bacterial Infections and Vaccines
- Viral gastroenteritis research and epidemiology
- Actinomycetales infections and treatment
- Bacterial Identification and Susceptibility Testing
- Escherichia coli research studies
- Ear Surgery and Otitis Media
- Streptococcal Infections and Treatments
- SARS-CoV-2 and COVID-19 Research
- Respiratory and Cough-Related Research
- Energy and Environment Impacts
- Global Health and Epidemiology
- Syphilis Diagnosis and Treatment
Manmohan Memorial Institute of Health Sciences
2017-2023
University of Oxford
2023
Science Oxford
2023
Tribhuvan University
2012-2022
Tribhuvan University Teaching Hospital
2010-2021
Kathmandu University
2014
University of Maine
2012
BRAC
2004
Healthcare associated infections (HCAI) and antimicrobial resistance are principal threats to the patients of intensive care units major determining factors for patient outcome. They with increased morbidity, mortality, excess hospitalization financial costs. The present study is an attempt investigate spectrum bacterial isolates involved in healthcare a critical unit at tertiary university hospital Kathmandu, Nepal. A laboratory based was conducted over period 15 months (January 2014 March...
Urinary tract infections (UTI) represent the most common bacterial among patients visiting outpatient clinics of healthcare centers in Nepal. However, treatment such is compounded by emergence and spread multidrug-resistant uropathogens associated with extended-spectrum β-lactamases (ESBLs). In this study, we aimed to investigate burden antimicrobial resistance occurrence ESBL genes clinical isolates uropathogenic Escherichia coli at a tertiary care teaching hospital During study period,...
Infections caused by bacteria such as multidrug resistant (MDR) Acinetobacter spp. and methicillin-resistant Staphylococcus aureus (MRSA) constitute a worldwide pandemic. Without gathering information about these strains, we cannot reduce the morbidity mortality due to infections notorious bugs. This study was conducted identify status of MDR MRSA in tertiary care centre Nepal. Sputum, endotracheal aspirate bronchial washing specimens were collected processed from patients suspected lower...
Candida species are responsible for various clinical infections ranging from mucocutaneous infection to life threatening invasive diseases along with increased resistance antifungal drugs has made a serious concern. Resistance agents during the last decade. Thus, identification of up level and its susceptibility testing paramount significance in management Candidal infections. The aim study was speciate determine pattern agents.A total 100 consecutive were isolated 1248 specimens over 7...
Background: The present study was conducted to assess knowledge, attitude, and practice of dental ergonomics among undergraduates (UGs), interns, postgraduate students (PGs) in a teaching hospital the Koshi province. Methods: A cross-sectional questionnaire-based tertiary care center. questionnaire distributed 228 their related ergonomics. responses obtained were presented terms frequency percentage. Results: In surveyed population, 211 (92.54%) aware musculoskeletal disorders practice,...
Fascioliasis is a zoonotic disease caused by Fasciola species. Patient may be asymptomatic or presents with jaundice and biliary colic right hypochondriac pain due to bile duct obstruction gastrointestinal symptoms.We report case of human fascioliasis in 45 years old female presented Tribhuvan University Teaching Hospital (TUTH), Kathmandu, Nepal on August, 2015 fever, pain, occasional vomiting anorexia for 4 months whose alkaline phosphatase was elevated peripheral blood smear revealed...
Diarrhoeal diseases are a major problem in developing countries. Though precise data on childhood mortality associated with diarrhoeal Nepal not available, it has been estimated that approximately 25 % of child deaths disease, particularly acute diarrhoea. The purpose this study was to assess the incidence rotavirus causing diarrhoea children less than 5 years age. A total 525 children’s hospital Kathmandu, Nepal, were enrolled between April and September 2011. due 25.9 (136/525) as...
<b>Objective</b> To determine, in one low income country (Nepal), which characteristics of medical students are associated with graduate doctors staying to practise the or its rural areas. <b>Design</b> Observational cohort study. <b>Setting</b> Medical college registry, internet, phone, and personal follow-up graduates. <b>Participants</b> 710 from first 22 classes (1983-2004) Nepal's college, Institute Medicine. <b>Main outcome measures</b> Career practice location (foreign Nepal; outside...
Pyogenic wound infections are one of the most common clinical entities caused and aggravated by invasion pathogenic organisms. Prompt aggressive antimicrobial therapy is needed to reduce burden complications associated with these infections. In this study, we intended investigate pathogens their susceptibility patterns from pyogenic at a tertiary care hospital in Kathmandu, Nepal. A laboratory based cross-sectional study was carried out among specimens patients visiting Manmohan Memorial...
In most developing countries, smear-negative pulmonary TB (SNPT) often gets missed from the diagnosis of consideration, though it accounts 30-65% total PTB cases, due to deficient or inaccessible molecular diagnostic modalities.The cross-sectional study enrolled 360 patients with clinical-radiological suspicion SNPT in Tribhuvan University Teaching Hospital (TUTH). The patient selection was done as per algorithm Nepal's National Tuberculosis Program (NTP) for Xpert MTB/RIF testing....
Background . Superficial mycosis is a common fungal infection worldwide, mainly caused by dermatophytes. However, the prevalence of species varies geographically. In addition, treatment best guided according to isolated. This study was carried out determine clinical as well mycological profile superficial mycoses in tertiary care hospital, Nepal. Methods prospective case-control laboratory based conducted over period six months from January June 2014 at Tribhuvan University Teaching...
Equations that relate individual tree diameter at breast height (d.b.h.) and total (HT) are important because HT is not widely measured often needed to estimate stem volume or predict growth. The primary goal of the study was construct a regional d.b.h. equation (H-D) for 15 species Acadian Region. Specific objectives were (1) evaluate performance Forest Vegetation Simulator Northeast Variant (FVS-NE) equations, (2) explore suitable model forms compare influence various tree- stand-level...
Extended-spectrum β-lactamase (ESBL)- and AmpC-β-lactamase AmpC-Enterobacteriaceae have recently emerged as a public threat in the treatment of nosocomial well community-acquired infections. Very little information is currently available about its existence Nepal. We, therefore, aim to determine prevalence ESBL AmpC.During 6-month period (November 2014-April 2015), total 190 stool specimens from participants were obtained different population. Of 260 fecal isolates, 152 outpatient department...
Shigella is an important cause of bacterial gastroenteritis in resource-poor countries. The treatment shigellosis mostly requires antibiotics. However, the increase multidrug resistance along with emergence extended-spectrum β-lactamase and ciprofloxacin among spp. has challenged situation. This study was conducted to determine distribution species antibiotic susceptibility pattern isolated from stool specimen children less than 5 years age Nepal.Out total 717 samples collected, 15 cases...
Invasive pneumococcal disease is a significant cause of morbidity and mortality worldwide it major for childhood deaths in Nepal.The aim this study was to establish the antimicrobial susceptibility pattern Streptococcus pneumoniae perform serotype responsible Nepal.All together 3774 children from 2 60 months who fulfilled enrollment criteria suspect bacterial pneumonia, sepsis or meningitis were enrolled etiologic studies severe illness. During period isolates isolated testing serotyping...
Pulmonary nocardiosis is an opportunistic infection in immunocompromised patient; however, often neglected the immunocompetent patient from diagnosis considerations. We describe a case of pulmonary masquerading renascence tuberculosis, 51-years-Nepali farmer. After 6 month presumed successful antitubercular therapy; develops clinical presentations and radiological features showing similarities with that tuberculosis malignancy. MTB complex was not detected Xpert MTB/RIF assay cytological...
Nocardiosis is an opportunistic infection in a patient with underlying immune suppression and organ transplant. Clinical syndromes are varied ranges from pulmonary, disseminated, cutaneous along central nervous system involvement. Herein, we report rare case of disseminated pulmonary nocardiosis cerebral manifestation 66 year-old-Nepali farmer; history renal transplantation undergoing therapy for tuberculosis. Radiographic imaging revealed multiple opacities varying sizes bilateral lung...