A5011264402- Antimicrobial Resistance in Staphylococcus
- Streptococcal Infections and Treatments
- Bacterial Identification and Susceptibility Testing
- Diabetic Foot Ulcer Assessment and Management
- Long-Term Effects of COVID-19
- Acute Myocardial Infarction Research
- Tuberculosis Research and Epidemiology
- Atrial Fibrillation Management and Outcomes
- Antibiotic Use and Resistance
- Pneumonia and Respiratory Infections
- Antiplatelet Therapy and Cardiovascular Diseases
- Pneumocystis jirovecii pneumonia detection and treatment
- Pediatric health and respiratory diseases
- COVID-19 Clinical Research Studies
- Surgical site infection prevention
- Clostridium difficile and Clostridium perfringens research
- Neutropenia and Cancer Infections
- Pharmacy and Medical Practices
- Intensive Care Unit Cognitive Disorders
- Hemodynamic Monitoring and Therapy
- Coronary Interventions and Diagnostics
- Neuroinflammation and Neurodegeneration Mechanisms
- Healthcare professionals’ stress and burnout
- Pharmaceutical Practices and Patient Outcomes
- COVID-19 and healthcare impacts
Audie L. Murphy Memorial VA Hospital
2019-2024
South Texas Veterans Health Care System
2019-2023
The University of Texas Health Science Center at San Antonio
2020-2021
The University of Texas at Austin
2021
The University of Texas Health Science Center at Houston
2020-2021
Austin College
2021
Murphy Oil Corporation (United States)
2019
Michael E. DeBakey VA Medical Center
2016-2019
The University of Texas MD Anderson Cancer Center
2017
Methodist University Hospital
2014
The risk of severe coronavirus disease 2019 (COVID-19) varies significantly among persons similar age and is higher in males. Age-independent, sex-biased differences susceptibility to COVID-19 may be ascribable deficits a sexually dimorphic protective attribute that we termed immunologic resilience (IR).
Dual antiplatelet therapy (DAPT) has been found to reduce the risk of cardiac death, myocardial infarction, stroke, and stent thrombosis following acute coronary syndrome percutaneous intervention. However, this also shown increase gastrointestinal (GI) bleeding as high 2-fold, especially in patients with multiple factors. Proton pump inhibitor (PPI) decreases risk. The current consensus document on reducing GI risks associated agents no longer recommends PPI for all receiving aspirin (ASA)...
Abstract Background Diabetic Foot Infection (DFI) guidelines recommend empiric methicillin-resistant Staphylococcus aureus (MRSA)-targeted therapy in settings where there is high prevalence of MRSA infections or cases severe infection; however, they do not provide recommendations for de-escalation. This approach has the potential to increase unnecessary use broad-spectrum antibiotics; therefore, additional strategies are needed optimize appropriate antibiotic use. study evaluates effect...
Infectious Diseases Society of America diabetic foot infection (DFI) guidelines indicate empiric methicillin-resistant Staphylococcus aureus (MRSA) coverage for patients with a history MRSA infection, when local prevalence is high, or clinically severe. These recommendations may lead to overutilization coverage, which can result in serious consequences. A strong negative predictive value (NPV) has been reported literature pneumonia, and recently, all anatomical sites infection. While these...
Abstract Background The use of third generation cephalosporins (3GC) has been linked to collateral damage such as increased risk infection with C. difficile, ESBL-producing organisms, VRE, and MRSA. Reduction in 3GC shown reduce prevalence these infections, particularly difficile ESBLs. An increase was observed at our facility 2019 2020, likely due targeted fluoroquinolone reduction initiatives COVID-19 surges 2020. A multifaceted intervention targeting without restriction implemented...
Abstract Background Rapid diagnostic testing (RDT) in microbiology labs shortens the time to identification of bacteria blood cultures. This study evaluates impact implementation Cepheid® GeneXpert® detect methicillin-resistant Staphylococcus aureus and S. Gram-positive Methods Patients with positive cultures for spp. before (November 2015–August 2016) after 2017–8/2018) a new rapid technology were evaluated. RDT results reviewed once daily by antimicrobial stewardship team. The primary...
Abstract Background DFI guidelines recommend empiric MRSA-targeted therapy in settings of high prevalence or severe infection; however, they do not provide recommendations for de-escalation. This approach has the potential to increase unnecessary use broad-spectrum antibiotics; therefore, additional strategies are needed optimize appropriate antibiotic use. study evaluates effect MRSA nasal PCR testing on and clinical outcomes patients with DFI. Methods was a retrospective quasi-experimental...