A5115602855- Quantum Chromodynamics and Particle Interactions
- Particle physics theoretical and experimental studies
- Black Holes and Theoretical Physics
- High-Energy Particle Collisions Research
- Dark Matter and Cosmic Phenomena
- Computational Physics and Python Applications
- Atomic and Subatomic Physics Research
- Neutrino Physics Research
- Particle Accelerators and Free-Electron Lasers
- Nuclear physics research studies
- Epigenetics and DNA Methylation
- Single-cell and spatial transcriptomics
- Autophagy in Disease and Therapy
- Advanced Algebra and Geometry
- Immune Cell Function and Interaction
- Cancer Immunotherapy and Biomarkers
- Coding theory and cryptography
- Algebraic and Geometric Analysis
- Cancer, Hypoxia, and Metabolism
Sixth Affiliated Hospital of Sun Yat-sen University
2024-2025
Sun Yat-sen University
2020-2025
Yunnan University
2024
Abstract Background Tumour immune macroenvironment is comprised of tumour and surrounding organs responding to tumourigenesis immunotherapy. The lack comprehensive analytical methods hinders its application for prediction survival treatment response in colorectal cancer (CRC) patients. Methods Cytometry by time‐of‐flight (CyTOF) RNA‐seq was applied characterise cell heterogeneity a discovery cohort including tumour, blood intestinal architecture comprising epithelium, lamina propria,...
ABSTRACT Objectives Methylenetetrahydrofolate dehydrogenase 1 (MTHFD1) is the enzyme with activities of methylenetetrahydrofolate dehydrogenase, cyclohydrolase, and formyltetrahydrofolate synthetase. Our aim was to elucidate function MTHFD1 in colorectal cancer (CRC). Methods In vitro assessments proliferation, invasion, migration abilities CRC cells were conducted using Immunohistochemistry, Transwell invasion assays, Western blot (WB), Cell counting Kit‐8 assays. WB also utilized measure...