A5102481734- Cardiovascular Function and Risk Factors
- Cardiac Imaging and Diagnostics
- RNA Research and Splicing
- RNA and protein synthesis mechanisms
- RNA modifications and cancer
- Advanced MRI Techniques and Applications
- Cardiac Valve Diseases and Treatments
- Advanced Photocatalysis Techniques
- Cardiomyopathy and Myosin Studies
- Copper-based nanomaterials and applications
- Cardiac pacing and defibrillation studies
- Advanced Nanomaterials in Catalysis
- X-ray Diffraction in Crystallography
- Congenital Heart Disease Studies
- Atrial Fibrillation Management and Outcomes
- Covalent Organic Framework Applications
- Vehicular Ad Hoc Networks (VANETs)
- ECG Monitoring and Analysis
- Pharmacovigilance and Adverse Drug Reactions
- Metal-Organic Frameworks: Synthesis and Applications
- Flow Measurement and Analysis
- Cardiac Structural Anomalies and Repair
- EEG and Brain-Computer Interfaces
- Crystallization and Solubility Studies
- Coronary Artery Anomalies
Shanghai Mental Health Center
2024-2025
Shanghai Jiao Tong University
2024-2025
Sichuan University
2018-2025
West China Hospital of Sichuan University
2019-2024
Zhejiang University
2024
Jiangnan University
2024
Huaibei Normal University
2023
Changzhou University
2023
Yunnan University
2021-2023
Shanghai Medical College of Fudan University
2023
Early detection of subclinical myocardial dysfunction in patients with diabetes mellitus (DM) is essential for recommending therapeutic interventions that can prevent or reverse heart failure, thereby improving the prognosis such patients. This study aims to quantitatively evaluate left ventricular (LV) deformation and perfusion using cardiovascular magnetic resonance (CMR) imaging type 2 (T2DM), investigate association between LV coronary microvascular perfusion. We recruited 71 T2DM 30...
Diabetic peripheral neuropathy (DPN) has been shown to be independently associated with cardiovascular events and mortality. This study aimed evaluate changes in left ventricular (LV) microvascular perfusion myocardial deformation type 2 diabetes mellitus (T2DM) patients without DPN, as well investigate the association between LV deformation.Between October 2015 July 2022, one hundred twenty-three T2DM fifty-four DPN sixty age‑ sex‑matched controls who underwent magnetic resonance imaging...
The olanzapine/samidorphan (OLZ/SAM) combination is being regarded as a new strategy to combat weight gain induced by olanzapine (OLZ), and its safety of significant concern. Specifically, samidorphan an opioid receptor-related drug, issues related potential for dependence withdrawal symptoms deserve attention. This study aims provide comprehensive analysis adverse events (AEs) associated with the OLZ/SAM. pharmacovigilance based on reports from FDA Adverse Event Reporting System (FAERS)...
Metabolic syndrome (MetS) is a known risk factor for cardiovascular dysfunction; however, its impact on left ventricular (LV) global strains and myocardial energetic efficiency in non-ischemic dilated cardiomyopathy (NIDCM) remains inadequately understood. This study aimed to investigate the effect of MetS LV dysfunction NIDCM patients using magnetic resonance (CMR) imaging. A total 557 (378 without 179 with MetS) who underwent CMR examination were included. CMR-derived strains, remodeling...
Abstract The aim of this study was to investigate left ventricular (LV) global myocardial strain and LV involvement characteristics in patients with arrhythmogenic right dysplasia/cardiomyopathy (ARVD/C) evaluate their predictive value adverse cardiac events. Sixty consecutive ARVD/C a definite diagnosis who underwent CMR examination thirty-four healthy controls were enrolled retrospectively. images analyzed for the presence involvement. endpoint defined as composite sustained tachycardia or...
Abstract Background Metabolic syndrome (MetS) is a cluster of metabolic abnormalities that collectively cause an increased risk type 2 diabetes mellitus (T2DM) and nonatherosclerotic cardiovascular disease. This study aimed to evaluate the role myocardial steatosis in T2DM patients with or without MetS, as well relationship between subclinical left ventricular (LV) dysfunction steatosis. Methods materials We recruited 53 20 healthy controls underwent cardiac magnetic resonance examination....
BackgroundDiabetes mellitus-related cardiomyopathy has recently been described as a distinct progression of left ventricular (LV) systolic and diastolic dysfunction. Pathological changes in the myocardium may explain development two different phenotypes. We evaluated effects LV geometry, myocardial microcirculation, tissue characteristics on cardiac deformation patients with subclinical type 2 diabetes mellitus (T2DM) utilizing multiparametric magnetic resonance (CMR) imaging.MethodsA total...
Background Hypertension (HTN) and type 2 diabetes mellitus (T2DM) are both associated with left ventricular (LV) atrial (LA) structural functional abnormalities; however, the relationship between atrium ventricle in this population is unclear. Purpose To identify differences hypertensive patients without T2DM as basis for further investigation atrioventricular coupling relationship. Study Type Cross‐sectional, retrospective study. Population 89 [HTN (T2DM−)] (age: 58.4 +/− 11.9 years, 48...
Abstract Background The microvascular effects of obesity should be considered in diabetic individuals for elucidating underlying mechanisms and developing targeted therapies. This study aims to determine the effect on myocardial function type 2 diabetes mellitus (T2DM) patients using cardiac magnetic resonance (CMR) first-pass perfusion imaging assessed significant risk factors dysfunction. Materials methods Between September 2016 May 2018, 120 with T2DM (45.8% women [55 120]; mean age,...
To determine the feasibility of deformation analysis in right ventricle (RV) using cardiovascular magnetic resonance myocardial feature tracking (CMR-FT) type 2 diabetes mellitus (T2DM) patients. We enrolled 104 T2DM patients, including 14 with impaired ventricular ejection fraction (RVEF) and 90 preserved RVEF, 26 healthy controls this prospective study. CMR was used to RV feature-tracking parameters. strain parameters were compared among controls, patients reduced RVEF. Binary logistic...
Differentiating cardiac amyloidosis (CA) from hypertrophic cardiomyopathy (HCM) remains a clinical challenge, particularly in those with preserved left ventricular ejection fraction (LVEF) and similar hypertrophy. This study aimed to use global function index (LVGFI) myocardial contraction (MCF) discriminate CA HCM without using contrast agents on cardiovascular magnetic resonance imaging (CMR). In total, we included 68 patients, 90 35 healthy controls. We found that LVGFI had excellent...
Abstract Background Functional mitral regurgitation (FMR) is one of the most common heart valve diseases in diabetes and may increase left ventricular (LV) preload aggravate myocardial stiffness. This study aimed to investigate aggravation FMR on deterioration LV strain type 2 mellitus (T2DM) patients explore independent indicators peak (PS). Materials methods In total, 157 T2DM (59 with 98 without FMR) 52 age- sex-matched healthy control volunteers were included underwent cardiac magnetic...
Abstract Background Diabetic peripheral neuropathy (DPN) is the most prevalent complication of diabetes, and has been demonstrated to be independently associated with cardiovascular events mortality. This aim this study was investigate subclinical left ventricular (LV) myocardial dysfunction in type 2 diabetes mellitus (T2DM) patients without DPN. Methods One hundred thirty T2DM DPN, 61 DPN 65 age sex-matched controls who underwent magnetic resonance (CMR) imaging were included, all subjects...
Functional mitral regurgitation (FMR) in type 2 diabetes mellitus (T2DM) patients induced by left ventricular (LV) enlargement and valve abnormality may aggravated the impairment atrial (LA) compliance. Thus, this study aimed to depict how FMR LV dysfunction affect LA compliance T2DM with FMR.A total of 148 49 age- sex-matched normal controls underwent cardiac magnetic resonance examination. longitudinal strain functional indices were compared among different patients. The multivariate...