- Food Allergy and Anaphylaxis Research
- Allergic Rhinitis and Sensitization
- Asthma and respiratory diseases
- Contact Dermatitis and Allergies
- Drug-Induced Adverse Reactions
- Eosinophilic Esophagitis
- Respiratory and Cough-Related Research
- Urticaria and Related Conditions
- Dermatology and Skin Diseases
- Mast cells and histamine
- Ocular Surface and Contact Lens
- Pharmaceutical studies and practices
- Inhalation and Respiratory Drug Delivery
- Child Nutrition and Feeding Issues
- Corneal Surgery and Treatments
- Autoimmune Bullous Skin Diseases
- Ocular Infections and Treatments
- Eosinophilic Disorders and Syndromes
- Sinusitis and nasal conditions
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Celiac Disease Research and Management
- Biotechnology and Related Fields
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Occupational exposure and asthma
- Immunodeficiency and Autoimmune Disorders
University of Florence
2016-2025
Meyer Children's Hospital
2015-2024
Istituti di Ricovero e Cura a Carattere Scientifico
2023-2024
University of Udine
2021-2022
Temple Street Children's University Hospital
2015-2020
University of Pavia
2020
Meyer Children's Hospital
2009
University of Genoa
2003-2007
Uniwersytecki Szpital Dziecięcy
2006
Children's Clinical University Hospital
2006
Food Protein-Induced Enterocolitis Syndrome (FPIES) is a non-IgE-mediated paediatric disorder triggered by the ingestion of specific food proteins. Many features this syndrome are not yet well defined.The aim our study was to describe demographic features, causative agents, clinical treatments and outcomes children suffering from acute FPIES at three Italian Pediatric Allergology Centers.A retrospective performed over 7-year period (2004-2010). Hospital medical record databases hospital...
<h3>Abstract</h3> <b>Objective:</b> To determine the risk factors for and timing of vertical transmission hepatitis C virus in women who are not infected with HIV-1. <b>Design:</b> Follow up a median 28 (range 24-38) months babies born to antibodies but <b>Subjects:</b> 442 mothers babies, whom 403 completed study. <b>Main outcome measures:</b> Presence viral RNA alanine aminotransferase activity babies. RNA, method infection C, delivery, type infant feeding mothers. <b>Results:</b> 13...
Despite the importance of anaphylaxis, little information is available on its clinical features.To evaluate and allergologic features anaphylaxis in children referred to allergology immunology unit A. Meyer Children's Hospital (Florence, Italy) from 1994 1996.Ninety-five episodes occurred 76 (50 boys 26 girls). Sixty-six (87%) had only one episode while 10 (13%) two or more episodes. Sixty-two (82%) patients a personal history atopic symptoms, although 14 (18%) did not. Sixty (79%) studied...
The study describes the demographic features, culprit foods, clinical features and outcomes for children presenting with acute fish and/or shellfish food protein-induced enterocolitis syndrome (FPIES) in four Italian paediatric allergy centres.A retrospective/prospective was undertaken. All diagnosed or FPIES were enrolled. diagnosis of based on Sicherer's Miceli Sopo criteria. Skin prick tests (SPT) performed all patients, at time prior to OFC.Seventy Mean age first episode 14 months (range...
The therapeutic strategy for children with cow's milk allergy (CMA) consists in the elimination of (CM) from their diet. Donkey's (DM) has been reported to be an adequate alternative, mainly his nutritional similarities human (HM) and excellent palatability. aim present prospective study was evaluate impact DM on diet CMA term growth.Before trial during health hygiene risks nutraceuticals parameters were monitored. Children identified by execution vivo vitro tests CM subsequent assessment...
We evaluated the prevalence of gastroesophageal reflux in 36 children, 22 (61.2%) male and 14 (38.8%) female (median age, 75.5 months; range, 18-178), with noncontrolled asthma by means prolonged (22-24 h) esophageal pH monitoring. None children had gastrointestinal symptoms suggesting reflux. Atopy was seen 21 (58.3%) patients. Pathological present 27 (75%) children. All patients were given cisapride (0.2 mg/kg q.i.d.) for 3 months. A clinical pharmacological score determined, a second...
Possible associations between allergy to grass pollen and positive skin tests food allergens were studied in 102 children monosensitized (as inhalant allergens) pollen, 117 Dermatophagoides . Thirty‐two foods tested by an epicutaneous method. Positive more frequent with (59.8%) than (9.4%). A considerably high frequency of reactions tomato (39.2%), peanut (22,5%), green pea (13.7%), wheat (11.7%) was observed pollen. closely correlated RAST results nasal provocation tests, whereas test...
Vernal keratoconjunctivitis (VKC) is a chronic and potentially sight-threatening disease. Topical corticosteroids (Cs) seem to be the only effective treatment for this condition, although severe side effects may occur owing their prolonged use. More recently, cyclosporine (Cyc) eye drops have been reported as valid alternative, but so far such has successfully experimented short time in small numbers of patients. The aim our study evaluate long term safety efficacy topical children suffering...
Abstract Background Vernal keratoconjunctivitis ( VKC ) is a chronic sight‐threatening ocular disease. Topical cyclosporine A (Cyc) has been widely administered as steroid‐sparing drug, although in about 7–10% of cases, it ineffective. The purpose this study was to evaluate the efficacy 0.1% topical tacrolimus (Tcr) patients with severe who failed respond 1% Cyc eyedrops. Methods Consecutive severe, Cyc‐resistant were enrolled double‐blind, comparative, crossover DBCO trial; all treated one...
Cow's milk is considered the best wholesome supplement for children since it highly enriched with micro and macro nutrients. Although protein fraction composed of more than 25 proteins, only a few them are capable triggering allergic reactions in sensitive consumers. The balance composition plays an important role sensitization capacity cow's milk, its modification can increase immunological response patients. In particular, heating treatments presence food matrix have demonstrated decrease...
Abstract Knowledge on multiple interdependences between quality of life (QoL) and behavioural problems in relation to asthma severity control is undetermined. The aims the study were: (i) assess relationship QoL with (ii) predict children’s “abnormal/borderline” status variation QoL. For these purposes a multicenter case-control 47 Severe Asthma (SA) 94 Moderate (MA) children was performed. MIMIC approach applied investigate effect SA non-controlled (NC) disorders. Logistic regression used...