A5011111305- Celiac Disease Research and Management
- Clinical Nutrition and Gastroenterology
- Child Nutrition and Feeding Issues
- Diet and metabolism studies
- Childhood Cancer Survivors' Quality of Life
- Cystic Fibrosis Research Advances
- Nutritional Studies and Diet
- Eosinophilic Esophagitis
- Helicobacter pylori-related gastroenterology studies
- Infant Nutrition and Health
- Digestive system and related health
- Nutrition and Health in Aging
- Infant Health and Development
- Gut microbiota and health
- Gastroesophageal reflux and treatments
- Microscopic Colitis
- Palliative Care and End-of-Life Issues
- MicroRNA in disease regulation
- Drug Transport and Resistance Mechanisms
- Breastfeeding Practices and Influences
- Metabolism and Genetic Disorders
- Liver Disease Diagnosis and Treatment
- Ovarian function and disorders
- Gastrointestinal disorders and treatments
- Renal function and acid-base balance
Ospedale Santa Maria
2006-2020
Azienda Sanitaria Unità Locale di Reggio Emilia
2013-2020
Istituti di Ricovero e Cura a Carattere Scientifico
2013-2020
Azienda Ospedaliera S.Maria
2007-2017
Santa Maria Nuova Hospital
2007-2014
University of Modena and Reggio Emilia
1989-2011
Ospedale "Santa Maria delle Croci" di Ravenna
2004-2009
Abertay University
2005
Boston Children's Hospital
1987-2000
Royal Hospital for Children
1994-1998
: There are many differences in diet and lifestyle across Europe that may influence the development of infant gut microbiota. This work aimed to assess impact geographic area, mode delivery, feeding method, antibiotic treatment on fecal microbiota infants from 5 European countries with different characteristics: Sweden, Scotland, Germany, Italy, Spain.: Fecal samples 606 (age 6 weeks) recruited within project INFABIO were analyzed by fluorescent situ hybridization combined flow cytometry...
The relationship between the risk of celiac disease and both age at which gluten is introduced to a child's diet early dietary pattern unclear.We randomly assigned 832 newborns who had first-degree relative with introduction 6 months (group A) or 12 B). HLA genotype was determined 15 age, serologic screening for evaluated 15, 24, 36 5, 8, 10 years. Patients positive findings underwent intestinal biopsies. primary outcome prevalence autoimmunity overt among children 5 years age.Of 707...
Although it is well established that early infant feeding has a major influence on the establishment of gut microbiota, very little understood about how introduction first solid food influences colonization process. This study aimed to determine impact weaning faecal microbiota composition infants from five European countries (Sweden, Scotland, Germany, Italy and Spain) which have different lifestyle characteristics practices. Faecal samples were collected 605 approximately 4 weeks after...
Abstract Background The PalliPed project is a nationwide, observational, cross-sectional study designed with the aim of providing constantly updated national database for census and monitoring specialized pediatric palliative care (PPC) activities in Italy. This paper presents results first phase project, which was developed through 2022–2023 study, to update current knowledge on provision PPC services Methods Italian centers/facilities were invited participate asked complete self-reporting,...
There is wide variation in the duration of breastfeeding across Europe which may part be due to between-country differences mothers' and societal attitudes towards public. The objective this study was quantify compare maternal to, practice of, public four European centers investigate association with breastfeeding.Participants (n = 389) were mothers recruited from maternity wards hospitals Glasgow (Scotland), Stockholm (Sweden), Granada (Spain), Reggio-Emilia (Italy).Among those who had...
Kawasaki disease (KD) is a febrile systemic vasculitis of unknown etiology and the main cause acquired heart among children in developed world. To date, abdominal involvement at presentation not recognized as risk factor for more severe form disease.To evaluate whether presenting manifestations identify group major Intravenous immunoglobulin (IVIG)-resistance coronary lesions.Retrospective study KD patients diagnosed between 2000 2015 13 pediatric units Italy. Patients were divided into 2...
Objective: MicroRNAs (miRNAs) are gene expression regulators. Altered miRNA levels associated with diabetes, insulin resistance, and inflammation. Insulin resistance inflammation both features of Polycystic ovary syndrome (PCOS). The aim this study was first to assess differences in selected miRNAs (miR-146a, miR-155, miR-320, miR-370, miR-486), involved sensitivity regulation inflammation, women or without PCOS. Second, investigate relationships among these miRNAs, insulin, High mobility...
Accurate estimation of the specialized pediatric palliative care (PPC) burden and definition extent quality PPC service in Italy represent urgent needs to enable proper allocation resources prevention educational plans. The PalliPed project aimed provide first comprehensive assessment characteristics Italian patients requiring PPC, regional networks/facilities, number dedicated resources. In this paper, we present results second part project, regarding implementation services Italy.
Abstract Knowledge on multiple interdependences between quality of life (QoL) and behavioural problems in relation to asthma severity control is undetermined. The aims the study were: (i) assess relationship QoL with (ii) predict children’s “abnormal/borderline” status variation QoL. For these purposes a multicenter case-control 47 Severe Asthma (SA) 94 Moderate (MA) children was performed. MIMIC approach applied investigate effect SA non-controlled (NC) disorders. Logistic regression used...
Children with cystic fibrosis have variable degrees of exocrine pancreatic insufficiency which, if untreated, is the main cause fat malabsorption. The impact enzyme supplementation on digestion was measured in 41 children fibrosis, 11 healthy controls, and five mucosal diseases by a non-invasive test intraluminal lipolysis using <sup>13</sup>carbon (<sup>13</sup>C) labelled mixed triglyceride (1,3-distearyl, 2[<sup>13</sup>C] octanoyl glycerol). without supplements had median...
Intestinal failure (IF) is the reduction in functioning gut mass below minimal level necessary for adequate digestion and absorption of nutrients fluids weight maintenance adults or growth children. There a paucity epidemiologic data on pediatric IF. The purpose this study was to determine prevalence, incidence, regional distribution underlying diagnosis chronic IF (CIF) requiring home parenteral nutrition (HPN) Italy.Local investigators were selected 19 Italian centers either reference HPN...
PCOS treatment should be based on pathophysiology. High-mobility-group-box-1 (HMGB1) was shown to increase in patients as a consequence of reduced cystic-fibrosis-transmembrane-conductance-regulator (CFTR) expression the ovary, and associated with insulin resistance inflammation, both features PCOS. Inositols ALA derivatives could have positive effects sensitivity, reduce androgens, improve ovulation rhythm. The aim this study verify changes HMGB1, metabolic endocrine parameters adolescents...
/Background: Sleep problems constitute a common and heterogeneous complaint in pediatric palliative care (PPC); they often contribute to disease morbidity cause additional distress children adolescents their families, already facing the burden of life-threatening life-limiting conditions. Despite significant impact sleep problems, clinical evidence is lacking. The application general medicine recommendations appears insufficient address unique challenges PPC dimension terms variability,...
Stable isotope breath tests offer a safe, repeatable non-invasive method of measuring fat digestion. They involve the ingestion substrate labelled with 13 C followed by serial measurements C: 12 ratio in expired CO 2 , from which percentage dose recovered (PDR) can be calculated. However PDR depends on -production rate. Our aim was to compare results obtained using directly measured rates those calculated two predicted values. Twelve normal healthy children and twenty-four cystic fibrosis...
The effectiveness of cimetidine (30–40 mg/ kg/day) was evaluated in 32 children with gastroesophageal reflux disease complicated by esophagitis who entered a random double-blind trial for 12 weeks. Esophagitis diagnosed all patients endoscopy biopsy. Seventeen (age, mean ± SD: 21.7 97.65 months) received (c-pts), and 15 29.03 39.73 placebo (p-pts). All intensive postural therapy. Based on clinical endoscopic (and histologic) data, c-pts three p-pts were healed (p < 0.01), the condition four...