- Infant Nutrition and Health
- Neonatal Respiratory Health Research
- Birth, Development, and Health
- Breastfeeding Practices and Influences
- Clinical Nutrition and Gastroenterology
- Infant Development and Preterm Care
- Celiac Disease Research and Management
- Child Nutrition and Feeding Issues
- Digestive system and related health
- Infant Health and Development
- Helicobacter pylori-related gastroenterology studies
- Obesity, Physical Activity, Diet
- Intestinal Malrotation and Obstruction Disorders
- Pediatric Hepatobiliary Diseases and Treatments
- Microbial Metabolites in Food Biotechnology
- COVID-19 Impact on Reproduction
- Probiotics and Fermented Foods
- Eosinophilic Esophagitis
- Microscopic Colitis
- Pediatric health and respiratory diseases
- Gastrointestinal disorders and treatments
- Childhood Cancer Survivors' Quality of Life
- Pregnancy and preeclampsia studies
- Body Composition Measurement Techniques
- Metabolism and Genetic Disorders
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
2015-2024
University of Milan
2013-2022
Aga Khan University
2022
Lurie Children's Hospital
2022
Bayero University Kano
2022
Aminu Kano Teaching Hospital
2022
Africa Center
2022
Hospital for Sick Children
2022
Hospital Clínico Universitario Lozano Blesa
2022
Ospedale Maggiore
2007-2021
Detailed information about the association of COVID-19 with outcomes in pregnant individuals compared not-infected is much needed.
Gastric acidity (GA) inhibitors, including histamine-2 receptor antagonists (H2 blockers) and proton pump inhibitors (PPIs), are the mainstay of gastroesophageal reflux disease (GERD) treatment. A prolonged GA inhibitor-induced hypochlorhydria has been suggested as a risk factor for severe gastrointestinal infections. In addition, number papers meta-analysis have shown an increased pneumonia in H2-blocker-treated intensive care patients. More recently, community-acquired associated with...
Although breast milk is the normative feeding for infants, breastfeeding rates are lower than recommended. We investigated difficulties experienced by mothers in first months after delivery and their association with early discontinuation. conducted a prospective observational study. Mothers singleton healthy term newborns at hospital discharge were enrolled and, three post-delivery, administered questionnaire on experience. Association among neonatal/maternal characteristics, support...
(Abstracted from JAMA Pediatr 2021;175:817–826) At the beginning of COVID-19 pandemic, extent risks a COVID infection during pregnancy were unknown. During start there only few studies published comparing outcomes between pregnant women with and without infections.
Significance The incidence of chronic inflammatory autoimmune conditions, such as celiac disease (CD), is increasing at an alarming rate. CD the only condition for which trigger, gluten, known. However, its etiology and pathogenesis remain incompletely defined recent studies suggest other environmental stimuli may play a key role in pathogenesis. Here, we prospectively examine trajectory gut microbiota starting 18 mo before onset 10 infants who developed did not. We identified alterations...
Breastfeeding is the normative standard for infant feeding. Despite its established benefits, different factors can affect breastfeeding rates over time. The purpose of this study was to evaluate determinants in healthy term newborns during first three months life. A prospective, observational, single-center conducted nursery Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico Milan, Italy. mother-baby dyads that were admitted Clinic January and February 2017 enrolled. Only babies with...
The supply of breast milk to preterm infants tends occur at a lower rate than that recorded among term infants. We aimed investigate the facilitators and barriers breastfeeding during hospital stay according experiences mothers gave birth premature requiring admission neonatal intensive care unit. A cross-sectional questionnaire survey was conducted. Mothers who had delivered newborn with gestational age ≤33 weeks care, entered study. Basic subjects’ characteristics infant feeding practices...
Late preterm infants account for the majority of births. They are at an increased risk neonatal mortality and morbidity less likely to initiate breastfeeding be exclusively breastfed discharge compared born term. The aim this study was identify facilitators barriers during hospital stays according experiences mothers late infants. We conducted a cross-sectional questionnaire survey. Mothers who intended breastfeed had given birth newborn admitted level I II care, with gestational age 34 0/7...
Abstract Background Celiac disease (CD) is an autoimmune digestive disorder that occurs in genetically susceptible individuals response to ingesting gluten, a protein found wheat, rye, and barley. Research shows genetic predisposition exposure gluten are necessary but not sufficient trigger the development of CD. This suggests other environmental stimuli early life, e.g., cesarean section delivery antibiotics or formula feeding, may also play key role CD pathogenesis through yet unknown...
The purpose was to assess in Italy the clinical features at diagnosis of inflammatory bowel disease (IBD) children.In 1996 an IBD register onset established on a national scale.Up end 2003, 1576 cases pediatric were recorded: 810 (52%) ulcerative colitis (UC), 635 (40%) Crohn's (CD), and 131 (8%) indeterminate (IC). In period 1996-2003 increase incidence from 0.89 1.39/10(5) inhabitants aged <18 years observed. more frequent among children between 6 12 (57%) but 20% patients had under age;...
Background the addition of oligosaccharides to infant formula has been shown mimic some beneficial effects human milk. The aim study was assess tolerance and safety a containing an innovative mixture in early infancy. Methodology/Principal Findings this performed as multi-center, randomized, double-blind, placebo-controlled trial including healthy term infants. Infants were recruited before age 8 weeks, either having started with feeding or being fully breast-fed (breastfeeding group)....
Reference %fat and total fat-free mass data is necessary for evaluating growth in infants. We aimed to develop longitudinal infants from birth 6 months of age. An observational, multicenter, prospective cohort study was conducted with assessments at birth, 1 week, 2 weeks, 1, 2, 3, 4, 5, Subjects were exclusively breast-fed enrolled three centers. Whole-body composition (i.e., % fat mass) assessed using air-displacement plethysmography (ADP) (PEA POD; Life Measurement, Concord, CA). Maternal...
Background: Fermented foods have been proposed to prevent common infectious diseases (CIDs) in children attending day care or preschool. Objectives: To investigate the efficacy of dietary supplementation with cow’s skim milk fermented probiotic Lactobacillus paracasei CBA L74 reducing CIDs Methods: Multicenter, randomized, double-blind, placebo-controlled trial on healthy (aged 12–48 months) consuming daily 7 grams L. (group A), placebo (maltodextrins group B) preschool during winter season....
Fortifying human milk contributes to the prevention of postnatal growth failure in preterm infants. Because natural variability milk, targeted fortification has been advocated. However, data regarding efficacy and safety prolonged are scarce. We aimed assess infants compared with standard fortification, as well effects on infant growth. conducted an interventional study during hospital stay healthy very low birth weight who were exclusively fed milk. Pools collected for 24 h analysed using...
Abstract Mother’s milk is the best choice for infants nutrition, however when it not available or insufficient to satisfy needs of infant, formula proposed as an effective substitute. Here, we report results a randomized controlled clinical trial (NCT03637894) designed evaluate effects two different dietary regimens (standard and Lactobacillus paracasei CBA L74-fermented formula) versus breastfeeding (reference group) on immune defense mechanisms (primary endpoint: secretory IgA,...
Human milk oligosaccharides (HMOs) have important and diverse biological functions in early life. This study tested the safety efficacy of a starter infant formula containing Limosilactobacillus (L.) reuteri DSM 17938 supplemented with 2'-fucosyllactose (2'FL).Healthy infants < 14 days old (n = 289) were randomly assigned to bovine milk-based L. at 1 × 107 CFU/g (control group; CG) or same added 1.0 g/L 2'FL (experimental EG) until 6 months age. A non-randomized breastfed group served as...