- Spine and Intervertebral Disc Pathology
- Cervical and Thoracic Myelopathy
- Spinal Fractures and Fixation Techniques
- Spinal Hematomas and Complications
- Heterotopic Ossification and Related Conditions
- Endometriosis Research and Treatment
- Bone health and osteoporosis research
- Medical Imaging and Analysis
- Hip and Femur Fractures
- Musculoskeletal pain and rehabilitation
- Blood transfusion and management
- Pelvic and Acetabular Injuries
- Bone Metabolism and Diseases
- Platelet Disorders and Treatments
- Case Reports on Hematomas
- Management of metastatic bone disease
- Scoliosis diagnosis and treatment
Peking University
2019-2025
Peking University Third Hospital
2019-2025
Ministry of Education of the People's Republic of China
2023-2025
Beijing Haidian Hospital
2022
Background: Osteoporotic vertebral fractures cause pain and disability, which result in heavy socioeconomic burden. However, the incidence cost of China are unknown. We aimed to assess clinically recognized among people aged 50 years older from 2013 2017. Materials Methods: This population-based cohort study was conducted by using Urban Employee Basic Medical Insurance (UEBMI) Resident (URBMI) data 2017, covered more than 95% Chinese population urban areas. Vertebral were identified primary...
ABSTRACT Objective During percutaneous endoscopic interlaminar discectomy (PEID), a range of technologies including medical robotics, visual navigation, and spatial registration have been proposed to expand the application scope success rate minimally invasive surgery. The use robotic technology in surgery is conducive improving accuracy reducing risk. This study aims introduce precise efficient targeting method tailored for robot‐assisted positioning under C‐arm fluoroscopy inPEID. Methods...
A basic experimental study.To elucidate the role and mechanism of interleukin (IL)-17A in thoracic ossification ligamentum flavum (TOLF).TOLF is characterized by replacement with ossified tissue one leading causes spinal stenosis. IL-17A an important member IL-17 family that has received widespread attention for its key contributions to regulation bone metabolism heterotopic ossification. However, it unclear whether involved TOLF.Cell counting kit-8 assay 5-ethynyl-2'-deoxyuridine staining...
Case-control study.To investigate the incidence of symptomatic spinal epidural hematoma (SSEH) and recognize its risk factors in a cohort patients undergoing posterior thoracic surgery isolation.From January 2010 to December 2019, who developed SSEH after underwent evacuation were enrolled. For each patient, 2 or 3 controls did not develop same procedures with similar complexity at section spine period collected. The preoperative intraoperative factors, blood pressure-related radiographic...
Objective Thoracic spinal stenosis (TSS) surgeries necessitate a substantial amount of allogeneic blood resources. However, the efficacy preoperative autologous donation (PABD) in TSS surgery has not been clearly evaluated. Therefore, we aimed to evaluate PABD for surgery. Methods This study is retrospective study. Totally 397 patients who underwent at our institution from January 2019 June 2023 were included. Propensity score matching (PSM) was used make and Non‐PABD groups comparable...
A retrospective study.The purpose of this study is to identify the incidences, causes, and risk factors 30-day unplanned reoperation posterior surgery for thoracic spinal stenosis (TSS) based on 1948 patients in a single center.Unplanned suggested be useful quality indicator spine surgery. However, who underwent TSS have not been well-established.We retrospectively analyzed clinical data from January 2011 December 2021. Statistical methods including univariate multivariate analyses were...
Study Design. A retrospective study. Objective. The aim of this study was to describe a novel posterior approach, circumspinal decompression technique “IV+V+VI” for ossification the longitudinal ligament (OPLL) or hard disc herniation (HDH) in thoracic spine and assess its safety efficacy. Summary Background Data. Thoracic myelopathy caused by OPLL HDH is rare but intractable disorder that can only be effectively treated with surgery. Nevertheless, few studies have reported on detailed...
Abstract Background Ossification of the ligamentum flavum (OLF) is most common cause thoracic spinal stenosis, and responds poorly to conservative treatment, making surgery only effective method. The existence dural ossification (DO) makes challenging increases risk intra-/post-operative complications. To date, several methods have been proposed identify DO, but either diagnostic accuracy low or feasibility poor. Therefore, aim this study propose a new imaging sign (Banner cloud sign, BCs),...
Background: Diffuse idiopathic skeletal hyperostosis (DISH) has been evaluated as a potential risk factor of poor surgical outcomes for lumbar spinal stenosis, whereas the influence DISH on neuroimaging characteristics and postoperative prognosis patients with thoracic myelopathy not established. Therefore, this study aimed to shed light issue. Methods: A monocentric enrolled 167 eligible ossification ligamentum flavum (TOLF), who were followed up at least 2 years. Clinico-radiological...
Retrospective cohort study.
To compare the complications and clinical scores of posterior lumbar intervertebral fusion (PLIF) in middle-aged older patients different ages, to assess risk PLIF providing a reference for treatment.The data 1 136 patients, who were more than 55 years old underwent between June 2013 2016, retrospectively analyzed. According age undergoing surgery, they divided into 3 groups as 55-64 old, 65-74 ≥75 old. The general characteristics, comorbidities, surgical three compared, with comparison...
Abstract Study Design: a retrospective study. Summary of Background Data: Long-level spinal instrumented fusion for DLS by intention eliminated motion in an attempt to alleviate pain, improve deformity, and reduce disability. However, this surgery considerably impaired performance activities daily living (ADL) due the resulting stiffness. The lumbar stiffness disability index (LSDI) was validated measure effect on functional activity, however, which might not be fully applicable elderly...
Abstract Background: Thoracic spinal stenosis (TSS) is a rare but intractable disease that fails to respond conservative treatment. decompression, which traditionally performed using high-speed drills and kerrison rongeurs, time-consuming technically challenging task. Unfavorable outcomes high incidence of complications are the major concerns. The development adaptation ultrasonic bone scalpel (UBS) has promoted its application in various operations, standard operating procedure thoracic...
Abstract Thoracic ossification of the ligamentum flavum (TOLF) is leading cause thoracic spinal stenosis with no specifc treatment available. IL-17A has received widespread attention for its key contribution in regulation bone metabolism and heterotopic ossification. However, it unclear whether involved TOLF. Our results showed that expression was elevated ossified tissue compared to normal flavum. In vitro experiments, stimulation promoted proliferation osteogenic differentiation cells...
Background: Osteoporotic vertebral fractures cause pain and disability, which result in heavy socioeconomic burden. However, the incidence cost of China are unknown.Methods: This population-based cohort study was conducted by using Urban Employee Basic Medical Insurance (UEBMI) Resident (URBMI) data from 2013 to 2017, covered more than 95% Chinese population urban areas. The clinically recognized among people aged 50 years older 2017 were calculated. Vertebral identified primary diagnosis...