A5025954767- Cardiac pacing and defibrillation studies
- Cardiac Arrhythmias and Treatments
- Cardiac electrophysiology and arrhythmias
- Cardiovascular Function and Risk Factors
- Cardiac Valve Diseases and Treatments
- ECG Monitoring and Analysis
- Cardiac Structural Anomalies and Repair
- Neurological disorders and treatments
- Cardiac Imaging and Diagnostics
- Infective Endocarditis Diagnosis and Management
- Heart Rate Variability and Autonomic Control
- Aortic Disease and Treatment Approaches
- Heart Failure Treatment and Management
- Biomedical and Chemical Research
- Mechanical Circulatory Support Devices
- Cardiac Arrest and Resuscitation
- Healthcare Technology and Patient Monitoring
- Non-Invasive Vital Sign Monitoring
- Wireless Body Area Networks
- Transplantation: Methods and Outcomes
- Flexible and Reconfigurable Manufacturing Systems
- Atrial Fibrillation Management and Outcomes
- Cardiomyopathy and Myosin Studies
- Cardiovascular and exercise physiology
- Neuroscience and Neural Engineering
Marienhospital Gelsenkirchen
2021-2025
Ruhr University Bochum
2004-2024
BG University Hospital Bergmannsheil Bochum
2013-2024
LWL-Universitätsklinik Hamm
2017
Klinikum Lüdenscheid
2008-2016
University Hospitals of the Ruhr-University of Bochum
2016
Hospital General Universitario Gregorio Marañón
2014
Katholisches Klinikum Bochum
2014
Azienda Ospedaliera S.Maria
2012
University of Rochester Medical Center
2012
Using more intervals to detect ventricular tachyarrhythmias has been associated with reducing unnecessary implantable cardioverter-defibrillator (ICD) therapies.To determine whether using 30 of 40 arrhythmias (VT) (long detection) during spontaneous fast VT episodes reduces antitachycardia pacing (ATP) and shock delivery than 18 24 (standard detection).Randomized, single-blind, parallel-group trial that enrolled 1902 primary secondary prevention patients (mean [SD] age, 65 [11] years; 84%...
Three trials demonstrated recently that a long detection window reduces implantable cardioverter-defibrillator (ICD) therapy in primary prevention patients. Avoid Delivering Therapies for Nonsustained Arrhythmias ICD Patients III (ADVANCE III) was the only trial enrolled both and secondary patients.Of 1902 patients ADVANCE trial, 477 received defibrillator prevention; 248 were randomly assigned to setting (30 of 40 intervals) 229 nominal (18 24 ventricular arrhythmias with cycle length ≤ 320...
The purpose of the trial was to quantify and compare efficacy two different sequences burst anti-tachycardia pacing (ATP) strategies for termination fast ventricular tachycardia.The prospective, multicenter, parallel randomized, enrolling patients with an indication implantable cardioverter-defibrillator implantation.From February 2004, 925 were randomized followed-up 12 months. Eight pulses ATP terminated 64% episodes vs. 70% in 15-pulse group (p = 0.504). Fifteen proved significantly...
A long-detection interval (LDI) (30/40 intervals) has been proved to be superior a standard-detection (SDI) (18/24 in terms of reducing unnecessary implantable cardioverter defibrillator (ICD) therapies. To better evaluate the different impact LDI and anti-tachycardia pacing (ATP) on painful shocks, we assessed all treated episodes ADVANCE III trial. total 452 fast (200 ms < cycle length ≤ 320 ms) arrhythmic were recorded: 284 138 patients SDI arm 168 82 (106/452 inappropriate detections)....
Abstract Background Routine and rapid screening of the liver, pleura, abdominal aorta during standard transthoracic echocardiographic (TTE) studies might result in better management patients referred for assessment. A total 7000 cases from different departments between 2022 to 2024 were enrolled, non-cardiac findings documented 589 (8.4%). We screened rapidly all these as a part our policy performing examination. The most detected abnormalities pleural effusion context heart failure (88%),...
Abstract Background Assessment of the ascending aorta beyond sinotubular junction using transthoracic echocardiography (TTE) is challenging. It recommended to move transducer upper intercostal spaces from left parasternal long-axis view (PLAX) get a better visualization aorta. During our daily practice, we noticed that adding both medial sliding as well clockwise rotation upwards movement would increase length imaged Methods The visualized was measured two techniques. first EACVI and second...
Background: There is a large overlap in the risk profiles and pathophysiologies of coronary artery disease (CAD) cerebrovascular macroangiopathy. Therefore, this study aimed to analyse whether findings CAD examination by angiography or cardio-computer tomography (cardio-CT) are predictive Methods: Our was prospective, bicentric, cross-sectional cohort study. A total 191 patients without earlier diagnosis who underwent cardio-CT scan for screening during clinical routine were serially...
Abstract Background The number of CIEDs implantations has steadily increased over the past decade and is one most common procedures in cardiology. There are approximately 230 actively implanting hospitals German federal state North Rhine-Westphalia (NRW) with 17.9 million inhabitants. A large variation implantation numbers exists between hospitals, from &lt; 10 to 1,234 cases per year. Peri-/post-operative complications (C) such as pneumothorax, hemothorax, pericardial effusion, pocket...
The Medtronic Attain Stability Quad lead is a quadripolar left ventricular (LV) with an active fixation helix assembly designed to fixate the within coronary sinus and pace nonapical regions of LV. primary objective this study was determine safety effectiveness novel LV lead.Patients standard indications for cardiac resynchronization therapy (CRT) were enrolled. All patients followed at 3 6 months post-implant every thereafter until closure. Pacing capture thresholds (PCTs) measured implant...
Patients with progressive chronic kidney disease (CKD) are at higher risk of infections and complications from cardiac implantable electronic devices (CIED). In patients a primary or secondary prophylactic indication, defibrillators (ICD) can prevent sudden deaths (SCD). We retrospectively compared transvenous-ICD (TV-ICD) intermuscularly implanted subcutaneous-ICD (S-ICD) associated complication rates together hospitalizations in recipients stage 4 disease.
Cardiac contractility modulation (CCM) signals are non-excitatory electrical delivered during the absolute refractory period intended to improve contraction and cardiac function. Clinical trials have shown that CCM treatment significantly improves exercise tolerance quality of life in symptomatic heart failure patients. Studies with therapy typically include delivery for 3, 5 or 7 h per day, although other configurations also commonly used. Each has been associated improved outcomes failure,...
This study sought to evaluate the effects of programming a long detection in single-chamber (VVI) implantable cardioverter-defibrillators (ICDs) multicenter prospective ADVANCE III (Avoid DeliVering TherApies for Non-sustained Arrhythmias ICD PatiEnts III) trial.Programming strategies may reduce unnecessary shocks and their adverse but date have been described only dual-chamber ICDs.A total 545 subjects (85% male; atrial fibrillation 25%, left ventricular ejection fraction 31%, ischemic...
Background:The evaluation of the QT interval in presence left bundle branch block (LBBB) is associated with challenge to discriminate native from prolongation due increase QRS duration.The newest formula evaluate LBBB suggests: modified during = measured minus 50% purpose this study therefore validate abovementioned clinical setting. Methods:Validation two separate groups patients: Patients who alternated between narrow and intermittent patients developed after transcatheter aortic valve...
Background: Cephalic vein cutdown (CVC) and subclavian puncture (SVP) are the most commonly used access sites for transvenous lead placement of cardiac implantable electronic devices (CIEDs). Limited knowledge exists about long-term patency vascular lumen housing leads. Methods: Among 2703 patients who underwent CIED procedures between 2005 2013, we evaluated phlebographies 162 scheduled an elective replacement (median 6.4 years after first operation). The were divided into four stenosis...
Cardiac resynchronization therapy (CRT) requires effective left ventricular (LV) pacing (i.e. sufficient energy and appropriate timing to capture). The AdaptivCRT™ (aCRT) algorithm serves maintain fusion during LV or biventricular pacing. This function was tested by comparing the morphological consistency of depolarizations percentage in CRT patients randomized aCRT vs. echo-optimization.Continuous recordings (≥20 h) unipolar electrograms from (n = 38) echo-optimized 22) were analysed....
Abstract Aims The objective of this paper is to assess whether cardiac contractility modulation (via the Optimizer System) plus standard care (SoC) a cost‐effective treatment for people with heart failure [New York Heart Association (NYHA) III, left ventricular ejection fraction 25–45%, and narrow QRS] compared against SoC alone from perspective English National Health Service. Methods results We developed regression equation‐based cost‐effectiveness model, using individual patient data...