A5054700042- Acute Ischemic Stroke Management
- Traumatic Brain Injury and Neurovascular Disturbances
- Intracerebral and Subarachnoid Hemorrhage Research
- Stroke Rehabilitation and Recovery
- Long-Term Effects of COVID-19
- Atrial Fibrillation Management and Outcomes
- Cerebrovascular and Carotid Artery Diseases
- Respiratory Support and Mechanisms
- Heart Rate Variability and Autonomic Control
- Cardiac Arrest and Resuscitation
- COVID-19 Clinical Research Studies
- Epilepsy research and treatment
- Health Systems, Economic Evaluations, Quality of Life
- COVID-19 epidemiological studies
- Intensive Care Unit Cognitive Disorders
- Congenital Heart Disease Studies
- Neurological Disorders and Treatments
- Healthcare Systems and Practices
- Healthcare cost, quality, practices
- Neurosurgical Procedures and Complications
- Venous Thromboembolism Diagnosis and Management
- COVID-19 and Mental Health
- Ultrasound in Clinical Applications
- Cardiac Valve Diseases and Treatments
- Chronic Obstructive Pulmonary Disease (COPD) Research
Marienhospital Gelsenkirchen
2025
University Hospital Carl Gustav Carus
2021-2025
Technische Universität Dresden
2021-2025
Klinik und Poliklinik für Neurologie
2023
BG University Hospital Bergmannsheil Bochum
2018-2019
Abstract Background Routine and rapid screening of the liver, pleura, abdominal aorta during standard transthoracic echocardiographic (TTE) studies might result in better management patients referred for assessment. A total 7000 cases from different departments between 2022 to 2024 were enrolled, non-cardiac findings documented 589 (8.4%). We screened rapidly all these as a part our policy performing examination. The most detected abnormalities pleural effusion context heart failure (88%),...
Abstract Background Assessment of the ascending aorta beyond sinotubular junction using transthoracic echocardiography (TTE) is challenging. It recommended to move transducer upper intercostal spaces from left parasternal long-axis view (PLAX) get a better visualization aorta. During our daily practice, we noticed that adding both medial sliding as well clockwise rotation upwards movement would increase length imaged Methods The visualized was measured two techniques. first EACVI and second...
Background: Direct oral anticoagulants (DOAC) are associated with an increased risk of hematoma expansion (HE) in spontaneous intracerebral hemorrhage (ICH). However, the critical DOAC level influencing this remains unclear. This study investigates impact levels on HE patients DOAC-associated ICH. Methods: We conducted a retrospective analysis ICH who had DOAC-calibrated anti-Xa or -IIa activity measured upon admission. Patients were categorized based clinically established cutoff for...
Abstract Background The low rate of organ donation in Germany has been linked to a deficit the detection patients with brain death (BD) hospitals. It is unclear how crisis-related health system disruptions, such as COVID-19 pandemic, affect this deficit. Methods Secondary data analysis anonymized from deceased acute injury Saxony, Saxony-Anhalt and Thuringia during pre-pandemic pandemic period (01/2019–12/2022). Pandemic phases were stratified according predominant SARS-CoV-2 variant....
Abstract Purpose The benefit of endovascular treatment (EVT) in patients with acute symptomatic isolated occlusion the internal carotid artery (ICA) without involvement middle and anterior cerebral arteries is unclear. We aimed to compare clinical safety outcomes best medical (BMT) versus EVT + BMT stroke due ICA occlusion. Methods conducted a retrospective multicenter study involving between January 2016 December 2020. stratified by matched groups using propensity score matching (PSM)....
Abstract Background The high incidence of stroke recurrence necessitates effective post-stroke care. This study investigates the effectiveness a case management-based care program in patients with acute and TIA. Methods In this prospective cohort study, TIA, ischemic or intracerebral hemorrhage were enrolled into 12-month (SOS-Care) along conventional Control received only included home phone consultations by managers, focusing on education, medical social needs guideline-based secondary...
The best therapeutic strategy for patients with mechanical heart valves (MHVs) having acute ischemic stroke during treatment vitamin K antagonists (VKAs) remain unclear. Being so, we compared the outcomes for: (i) full dose heparin along VKA (bridging therapy group) and (ii) restarting without (nonbridging group).For this multicenter observational cohort study, data on consecutive MHV was retrospectively collected from prospective registries. Propensity score matching (PSM) adopted to adjust...
3.560.1 vs. 3.360.1mm , p<0.05;) and by preserved mitochondrial structure (single area: 124.56 6.7vs.92.366.7 119.566.7 pixels; p<0.05;).Conclusion: TMZ did not affect early AF stabilization, but reduce AF-induced ROS production attenuated several hallmarks of structural remodeling.Adjunctive therapy with may be useful in preserving atrial function during AF.
Malignant middle cerebral artery infarction is a potentially life-threatening disease. Decompressive hemicraniectomy constitutes an evidence-based treatment practice, especially in patients under 60 years of age; however, recommendations with respect to postoperative management and particularly duration sedation lack standardization.This survey study aimed analyze the current situation malignant following neurointensive care setting.From 20 September 2021 31 October 2021, 43 members...
Abstract Background An automated digital screening tool (DETECT) has been developed to aid in the early identification of patients who are at risk developing brain death during critical care. Methods This prospective diagnostic accuracy study included consecutive ≥ 18 years admitted neurocritical care for primary or secondary acute injury. The DETECT searched routinely monitored patient data electronic medical records every 12 h a combination coma and absence bilateral pupillary light...
Background The optimal management of patients with symptomatic isolated internal carotid artery (ICA) occlusion is unknown. We aimed to assess whether endovascular treatment (EVT) compared standard medical care was associated improved functional outcomes in acute intracranial ICA without involvement the middle or anterior cerebral artery, that is, ICA‐I occlusion. Additionally, we compare ICA‐L/T occlusion, which involves themiddle and respectively. Methods analyzed data from highly...
Introduction: While observational data suggest that dexmedetomidine may have neuroprotective effects on ischemic brain, its clinical use in acute stroke is limited due to concerns about cerebral vasoconstriction. We aimed examine the impact of outcomes patients with anterior circulation large vessel occlusion (acLVO) requiring neurocritical care after endovascular therapy (EVT). Methods: extracted from our registry for consecutive acLVO who underwent EVT and subsequent (12/2019-12/2022)....
Abstract Introduction Cardiac Contractility Modulation (CCM) is a treatment for patients with heart failure reduced ejection fraction (HFrEF) providing improved myocardial molecular and biochemical characteristics thus exercise tolerance quality of life by application electrical signals during the absolute refractory period. Cardiopulmonary testing an integrative method to assess in insights circulatory, respiratory metabolic reactions exercise. The VE/VCO2-Slope (minute ventilation/carbon...
Background: Chronic obstructive pulmonary disease (COPD) is the third leading cause of death worldwide. Air pollution associated with a decrease in lung function and an increase inflammatory biomarkers, respiratory symptoms, hospital admissions due to several causes, including COPD exacerbations. Nevertheless, uncertainty exists on whether indoor air quality improvement could lead reduction morbidity COPD. Therefore, we aim prove efficacy High-Efficiency Particulate (HEPA) filters reduce...
Introduction: To explore kidney safety profile of osmotic diuretic mannitol in patients with malignant middle cerebral artery (MCA) infarction. Methods: We analyzed data from consecutive MCA infarction (01/2008-12/2017). Malignant was defined according to clinical and radiographic DESTINY criteria. Clinical laboratory variables were collected for all patients. compared endpoints including acute failure (AKF; Kidney Disease: Improving Global Outcomes [KDIGO] definition) hemodialysis between...