A5002116007- Cardiac pacing and defibrillation studies
- Cardiac Arrhythmias and Treatments
- Cardiac electrophysiology and arrhythmias
- Atrial Fibrillation Management and Outcomes
- Advanced MRI Techniques and Applications
- Neurological disorders and treatments
- Cardiac Imaging and Diagnostics
- Wireless Body Area Networks
- Cardiac Structural Anomalies and Repair
- Mechanical Circulatory Support Devices
- Cardiovascular Function and Risk Factors
- Cardiomyopathy and Myosin Studies
- Cardiovascular Syncope and Autonomic Disorders
- Electromagnetic Fields and Biological Effects
- Cardiac Valve Diseases and Treatments
- ECG Monitoring and Analysis
- Heart Failure Treatment and Management
- Neuroscience and Neural Engineering
- Advanced Battery Technologies Research
- Muscle activation and electromyography studies
- Cardiac Health and Mental Health
- Venous Thromboembolism Diagnosis and Management
- Anesthesia and Sedative Agents
- Wireless Power Transfer Systems
- Cardiac, Anesthesia and Surgical Outcomes
Deutsches Herzzentrum München
2016-2025
München Klinik
2013-2025
Deutsches Herzzentrum der Charité
2001-2025
Technical University of Munich
2015-2024
Institut für Qualitätssicherung und Transparenz im Gesundheitswesen
2021
Institute for Quality and Efficiency in Health Care
2021
Asklepios Klinik St. Georg
2020
German Centre for Cardiovascular Research
2016-2020
Klinik und Poliklinik für Psychotherapie und Psychosomatik
2019
Heart Rhythm Society
2016
Implantable cardioverter-defibrillator (ICD) therapy is clearly an effective for selected patients in definable populations. The benefits and risks of ICD are directly impacted by programming surgical decisions. This flexibility both a great strength weakness, which there has been no prior official discussion or guidance. It the consensus four continental electrophysiology societies that important clinical issues sufficient trial data to provide evidence-based expert document systematically...
Catheter ablation for ventricular tachycardia (VT) reduces the recurrence of VT in patients with implantable cardioverter-defibrillators (ICDs). The appropriate timing and its effects on mortality heart failure progression remain a matter debate. In life-threatening arrhythmias necessitating ICD implantation, we compared outcomes preventive (undertaken before implantation to prevent shocks VT) deferred after 3 VT. BERLIN study (Preventive Ablation Ventricular Tachycardia Patients With...
Supraventricular tachyarrhythmias are the main cause of inappropriate therapies in patients with conventional single chamber implantable cardioverter defibrillators (VVI-ICD). It was anticipated that dual (DDD-ICD), their capacity to analyze atrial and ventricular rhythm, could substantially reduce therapies.Our prospective study included 92 (87 men; mean age 61 +/- 12.7 years) who were randomly assigned a VVI-ICD (45 patients) or DDD-ICD (47 patients). Both groups followed for 7.5 3.5 7.6...
Cardiac disease and treatment with an implantable cardioverter-defibrillator (ICD) may be psychologically traumatic. Posttraumatic stress disorder (PTSD) is generally overlooked in cardiac patients, no study to date (to our knowledge) has evaluated the effect of PTSD symptoms on prognosis patients ICDs.To test whether at baseline predict long-term mortality risk ICDs.Prospective cohort a mean follow-up period 5.1 years, accounting for 743 person-years observed.Data were derived from Living...
ABSTRACT The vacuolating cytotoxin and the cytotoxin-associated protein, encoded by vacA cagA , respectively, are important virulence determinants of Helicobacter pylori . Sixty-five H. strains were isolated from dyspeptic patients (19 with peptic ulcer disease, 43 chronic gastritis, 3 gastric cancer) studied for differences in genes their relationship to VacA CagA expression, activity, clinical outcome infection. By PCR, fifty-four (83.1%) 65 had signal sequence genotype s1 only 10 (15.4%)...
Cryoablation has emerged as an alternative to radiofrequency catheter ablation (RFCA) for the treatment of atrioventricular (AV) nodal reentrant tachycardia (AVNRT). The purpose this prospective randomized study was test whether cryoablation is effective RFCA during both short-term and long-term follow-up with a lower risk permanent AV block.A total 509 patients underwent slow pathway (n=251) or (n=258). primary end point immediate failure, block, AVNRT recurrence 6-month follow-up....
Abstract Background Pulse field ablation (PFA) is a novel catheter technology with potential safety benefits due to its tissue selectivity. It has the directly damage or interact functionality of cardiac implantable electronic devices (CIEDs) in form electromagnetic interference (EMI). The aim our study was assess impact PFA on CIEDs. Methods lesions (45 per CIED) were applied from Farapulse system CIEDs (< 5 cm lead tip and < 15 generator). All checked before after application for...
Pulmonary vein isolation (PVI) is an established treatment for paroxysmal atrial fibrillation (AF). The ablation of complex fractionated electrograms (CFAE) has emerged as a novel approach. We sought to evaluate the additional effect CFAE PVI in AF.Ninety-eight patients with AF (57 +/- 10 years, 74 male) were randomized (n = 48) or + group 50). After PVI, was performed inducible group. primary endpoint combined objective (7-day Holter ECG) and subjective (symptoms) freedom tachyarrhythmia 3...
Introduction: Complex fractionated atrial electrograms (CFAE) have been described as a new target for ablation of fibrillation (AF). This prospective study evaluates the acute effects CFAE in patients with paroxysmal or persistent AF and analyzes preferential anatomic sites where these occur. Methods Results: Ablation was performed 66 symptomatic (mean age 58 ± 12 years) (n = 36) 30). Termination regularization during achieved 56 (84%), termination 28 (42%) (42%). showed no effect 10 (16%)....
Ablation of left atrial flutter (LAF) is often limited by the need for technically demanding linear lesions. We evaluated safety and efficacy a new modified anterior line (MAL), connecting anterior/anterolateral mitral annulus with superior pulmonary vein ablation perimitral flutter.MAL was performed in 65 patients (15 females, age 63.6 +/- 9.8 years) using 3D mapping systems (70.8% Carto, 29.2% NavX). Perimitral either presenting arrhythmia (73.8%) or an intermediate organized rhythm during...
Data about the acute and long-term outcome of catheter ablation in patients with D-transposition great arteries (d-TGA) post-Mustard/Senning operation are scarce. This single-centre retrospective analysis includes 26 (mean age 28.7 ± 6.7 years, 8 females) after Mustard (n = 15) or Senning 11) who underwent for intra-atrial re-entrant tachycardia (IART) atrioventricular nodal (AVNRT) from January 2004 to May 2011. The electrophysiological studies were performed using a three-dimensional...
This study aimed to evaluate the safety of continuous periprocedural rivaroxaban administration during left atrial radiofrequency ablation (RFA) in comparison with uninterrupted oral vitamin K antagonist administration. Data about use setting RFA procedures are lacking.The cohort included 544 patients (mean age, 63±10 years) who underwent between February 2012 and May 2013. All (n=272) receiving 15 or 20 mg/d before procedure (rivaroxaban) were matched by sex, type rhythm disorder an equal...
The OPTION (Optimal Anti-Tachycardia Therapy in Implantable Cardioverter-Defibrillator Patients Without Pacing Indications) trial sought to compare long-term rates of inappropriate shocks, mortality, and morbidity between dual-chamber single-chamber settings implantable cardioverter-defibrillators (ICDs) patients.The use ICDs potentially allows better discrimination supraventricular arrhythmias thereby reduces shocks. However, it may lead detrimental ventricular pacing.This prospective...
The modified anterior line (MAL) is an alternative to the mitral isthmus (MI) for treatment of perimitral atrial flutter (PMFL). We sought investigate acute and long-term efficacy this if routinely used PMFL.The cohort included 77 consecutive patients who underwent catheter ablation PMFL. was deployed between anterolateral annulus ostium left superior pulmonary vein. Perimitral either presenting arrhythmia after persistent fibrillation (AF) (Group 1, n = 42, 54.5%), occurring during AF 2,...
The aim of the study was to investigate whether type arrhythmia recurrence after ablation persistent atrial fibrillation (AF) has an impact on maintenance sinus rhythm repeat procedure.Included were 78 consecutive patients (82% men; mean age, 61±10 years; left diameter, 47±4 mm) with AF who underwent ≥1 ablation. initial procedure had consisted pulmonary vein isolation additional substrate modification (ablation complex fractionated electrograms [n=63] or linear lesions [n=15]). Patients...
The endpoint of persistent atrial fibrillation (AF) ablation is still a matter debate. purpose this study was to evaluate if sinus rhythm (SR) as AF has better long-term outcome compared tachycardia (AT) or at the end procedure.Between 2008 and 2011, 191 consecutive patients undergoing de novo catheter for symptomatic long-standing using sequential approach (including pulmonary vein isolation, complex fractionated electrograms linear lesions) were included in study. According result...
This joint consensus paper of the German Roentgen Society and Cardiac provides physical electrophysiological background information specific recommendations for procedural management patients with cardiac pacemakers (PM) implantable cardioverter defibrillators (ICD) undergoing magnetic resonance (MR) imaging. The outlines responsibilities radiologists cardiologists regarding patient education, indications, monitoring modification MR sequences PM/ICD reprogramming strategies being discussed...
Blood treated with an oral thrombin inhibitor demonstrates enhanced thrombus formation under flow conditions in humans and rodents.
Implantable cardioverter-defibrillator (ICD) therapy is clearly an effective for selected patients in definable populations. The benefits and risks of ICD are directly impacted by programming surgical decisions. This flexibility both a great strength weakness, which there has been no prior official discussion or guidance. It the consensus 4 continental electrophysiology societies that important clinical issues sufficient trial data to provide evidence-based expert document systematically...