A5073414467- Hepatitis B Virus Studies
- Hepatitis C virus research
- Hepatitis Viruses Studies and Epidemiology
- SARS-CoV-2 and COVID-19 Research
- Liver Disease Diagnosis and Treatment
- COVID-19 Clinical Research Studies
- Brucella: diagnosis, epidemiology, treatment
- HIV Research and Treatment
- HIV/AIDS drug development and treatment
- HIV, Drug Use, Sexual Risk
- Cervical Cancer and HPV Research
- HIV-related health complications and treatments
- HIV/AIDS Research and Interventions
- Vaccine Coverage and Hesitancy
- Burkholderia infections and melioidosis
- Immunotherapy and Immune Responses
- Parvovirus B19 Infection Studies
- vaccines and immunoinformatics approaches
- Tuberculosis Research and Epidemiology
- Genital Health and Disease
- Long-Term Effects of COVID-19
- Viral gastroenteritis research and epidemiology
- SARS-CoV-2 detection and testing
- Dermatological and COVID-19 studies
- Galectins and Cancer Biology
Pasteur Institute of Iran
2016-2025
Arak University of Medical Sciences
2012-2022
Clinical Research Management
2008-2016
Tehran University of Medical Sciences
2012-2015
University of Tehran
2012-2013
Iranian Center for Quantum Technologies
2011
GTx (United States)
2010
Shahid Beheshti University of Medical Sciences
2008
Shahid Beheshti University
2007
BackgroundBrucellosis is a zoonotic disease of worldwide distribution. Despite its control in many countries, it remains endemic Iran. The aim this study was to determine the risk factors for brucellosis acquisition central province Iran.MethodsA matched case–control conducted part A total 300 subjects (150 cases and 150 controls) were enrolled investigation. Brucellosis defined on basis epidemiologic, clinical, laboratory criteria. Subjects interviewed using questionnaire obtain factor...
ABSTRACT Cervical cancer is the fourth most common type of female malignancy worldwide. Although appropriate algorithms are available for precise HPV testing in order to manage women with abnormal Papanicolaou smears, region‐to‐region adoption really critical. The present study aimed at cervical cell cytology assessment as well genotyping specimens. A total 1047 samples who attended routine referral indications were examined four laboratories Varamin City (Tehran Province) from April 2021...
The optimal booster vaccine schedule against COVID-19 is still being explored. present study aimed at assessment of the immunogenicity and antibody persistency inactivated-virus based vaccine, BBIP-CorV protein-subunit vaccines, PastoCovac/Plus through heterologous homologous prime-boost vaccination. Totally, 214 individuals who were previously primed with BBIBP-CorV vaccines divided into three arms on their choice as regimens BBIBP-CorV/PastoCovac (n = 68), Plus 72) 74). PastoCovac...
Abstract Early reports on coronavirus disease 2019 (COVID-19) vaccines presented the short-term adverse events (AEs). This follow-up study investigated a standard regimen based protein subunit vaccines, PastoCovac and Plus, combinational vaccine regimens including AstraZeneca/PastoCovac Plus Sinopharm/PastoCovac Plus. The participants were followed up to 6 months post booster shot. All AEs collected through in-depth interviews using valid researcher-made questionnaire evaluated regarding...
Abstract Occult hepatitis B virus (HBV) infection is characterized by presence of HBV with undetectable surface antigen (HBsAg). harbors potential risk transmission through hemodialysis (HD). The aim this study was to assess the occult in patients isolated core antibody (anti‐HBc). A total 289 HD from five dialysis units Tehran, Iran, were included study. Hepatitis (HBsAg), (anti‐HBs), anti‐HBc, C (anti‐HCV), alanine aminotransferase (ALT) and aspartate (AST) levels tested all subjects....
This study explored the prevalence and related risk behaviors for hepatitis C (HCV), B (HBV), human immunodeficiency virus (HIV) among a sample of male injection drug users (IDUs) in Arak, Iran. One hundred IDUs attending methadone maintenance clinics between April September 2012 were enrolled evaluated HCV, HBV, HIV infection. The majority participants (56%) had evidence HCV exposure, 6% 19% HIV-infected. Coinfections frequent; 15% HBV 5% serologic markers all three infections. Most (84%)...
COVID-19 immunity in infected individuals may not be persistent. The specific response wanes patients who have recovered from this infection. Nevertheless, it has been fully understood whether true re-infection occurs or the viral reactivation. In study, we investigated three represented symptoms after recovery. Chest CT scan was applied to assess along with samples oropharyngeal/nasopharyngeal which were subjected RT-PCR. genome sequencing where possible distinguish latent Moreover,...
Data on immunogenicity, immune response persistency, and safety of COVID-19 boosters in patients with comorbidities are limited. Therefore, we aimed to evaluate three different boosters' immunogenicity individuals at least one underlying disease (UD) (obesity, hypertension, diabetes mellitus) healthy ones (HC) who were primed two doses the BBIBP-CorV vaccine received a booster shot same priming or protein subunit vaccines, PastoCovac Plus PastoCovac. One hundred forty subjects including...
COVID-19 pandemic has been managed through global vaccination programs. However, the antibody waning in various types of vaccines came to notice. Hereby, PastoCovac Plus as a protein subunit vaccine was investigated immunized health care workers by COVAXIN (BBV152). The booster recommended at least three months post second dose COVAXIN. Sera collection done before and after each injection. SARS-CoV-2 PCR test monthly detect any asymptomatic symptomatic breakthrough. 47.9 24.3% participants...
Background This study aimed at evaluation and comparison of PastoCovac Plus protein-subunit vaccine in parallel with ChAdOx1-S (AstraZeneca) BBIBP-CorV (Sinopharm) primarily vaccinated volunteers two doses or BBIBP-CorV. Materials methods 194 enrolled the who were previously primed 2 vaccines. They divided into heterologous regimens receiving a third dose Plus, homologous groups ChAdOx1-S. Serum samples obtained just before 4 weeks after booster dose. Anti-spike IgG neutralizing antibodies...
Given the limited available data about to number of vaccine doses administered over an extended time in Iran, immune status vaccinated individuals and any potential disparities this regard among those who received different numbers remain unknown. Therefore, study aimed assess humoral immunity COVID-19 vaccines Iran. This was conducted from February, 2022 December 2023 including 605 subjects. The durability anti-spike, anti-nucleocapsid (NCP), neutralizing antibody, interferon-γ (IFN-γ)...
Introduction: Anti-hepatitis B core antibody (Anti-HBc) alone is defined as the presence of anti-HBc in absence HBsAg and anti-HBs. The significance this serological pattern a predicting factor for occult hepatitis virus (HBV) infection remains largely unknown. This study aimed to assess HBV high-risk low-risk individuals. Methodology: A total 926 individuals were enrolled study, including 289 hemodialysis (HD) 106 HIV-infected patients who considered group 531 blood donors low-risk. HBsAg,...
Abstract Background and Aim: Host genetic environmental factors are viewed as a common basis of the different outcomes hepatitis B virus (HBV) infection. Human leukocyte antigen (HLA) plays an important role in immunological reaction to HBV In this study, we aimed determine association between infection HLA‐A, B, DRB1 alleles northern Iran. Methods: 33 patients with chronic (CHB) 31 healthy carriers persistent group, 30 subjects who had spontaneously recovered from were analyzed by using...
Occult hepatitis B virus (HBV) infection in blood donors is considered a potential threat for the safety of supply, however conclusive studies on this issue are lacking. The aim study was to assess occult HBV with isolated core antibody (anti-HBc) living city Arak, Central Province Iran, as low prevalence region HBV.A total 531 voluntary Iran were included study. Hepatitis surface antigen (HBsAg), (anti-HBs), anti-HBc, and C (anti-HCV) tested all subjects. presence HBV-DNA determined...
Human papillomavirus (HPV) infections are associated with benign and malignant lesions of the female male anogenital tract. Currently possible role HPV in prostate carcinogenesis is a subject great controversy. In this study we aimed to investigate infection carcinoma (PCa). The included formalin-fixed paraffin-embedded tissue samples 104 primary adenocarcinoma cases control tissues prostatic hyperplasia (BPH). HPV-DNA was purified amplified through MY09/MY11 GP5+/GP6+ primers subsequently...
In this era in which the vast majority of global population have developed COVID-19 infection and/or got vaccinated against it, identification late disorders as vaccines’ side effect or long-COVID manifestation seems essential. This study included individuals 4 different vaccine regimens including inactivated virus-based, subunit protein, and adenovirus-based vaccines a follow-up schedule 6-month post booster shot. All documented adverse events were thoroughly assessed considering cases’...
This study aimed to determine the prevalence of serological markers for hepatitis B virus (HBV), C (HCV), human immunodeficiency (HIV), and occult HBV infection among injection drug users (IDUs) with isolated anti-hepatitis core (anti-HBc).A total 153 male IDUs were tested surface (anti-HBs), antigen (HBsAg), anti-HBc, anti-HCV, anti-HIV. The presence HBV-DNA was determined in plasma samples individuals anti-HBc (HBsAg negative, anti-HBs positive) by polymerase chain reaction (PCR).The viral...
Detection of hepatitis B virus (HBV) DNA without detectable surfaceantigen (HBsAg) is defined as occult HBV infection. In patients co-infected with human immunodeficiency (HIV) and HBV, HIV interferes the natural history infection by enhancing replication, leading to more severe liver disease. The aim this study was assess in Iranian HIV-positive isolated core antibody (anti-HBc).The presence HBV-DNA determined quantitatively plasma samples HIV-infected anti-HBc real-time PCR using artus RG...