A5004571306- Blood Pressure and Hypertension Studies
- Health Systems, Economic Evaluations, Quality of Life
- Primary Care and Health Outcomes
- Pharmaceutical Practices and Patient Outcomes
- Chronic Disease Management Strategies
- Economic Growth and Productivity
- Agricultural Economics and Policy
- Inflammatory mediators and NSAID effects
- Pharmaceutical Economics and Policy
- Healthcare Policy and Management
- Antiplatelet Therapy and Cardiovascular Diseases
- Medication Adherence and Compliance
- Lipoproteins and Cardiovascular Health
- Patient-Provider Communication in Healthcare
- Appendicitis Diagnosis and Management
- Global Cancer Incidence and Screening
- Interprofessional Education and Collaboration
- Diabetes Management and Education
- Pharmaceutical industry and healthcare
- Cardiovascular Syncope and Autonomic Disorders
- Heart Rate Variability and Autonomic Control
- Innovation Policy and R&D
- Sodium Intake and Health
- Healthcare Systems and Technology
- Mobile Health and mHealth Applications
HealthPartners
2016-2025
University of Minnesota
2015-2024
Minnesota Department of Health
2023-2024
Bluebird Bio (France)
2023
University of St. Thomas - Minnesota
2023
University of Minnesota, Duluth
2021
Kaiser Permanente Center for Health Research
2016
Kaiser Permanente
2015
<h3>Importance</h3> Only about half of patients with high blood pressure (BP) in the United States have their BP controlled. Practical, robust, and sustainable models are needed to improve control uncontrolled hypertension. <h3>Objectives</h3> To determine whether an intervention combining home telemonitoring pharmacist case management improves compared usual care is maintained after stopped. <h3>Design, Setting, Patients</h3> A cluster randomized clinical trial 450 adults recruited from 14...
<h3>Importance</h3> Hypertension is a leading cause of cardiovascular disease. The results were previously reported trial home blood pressure (BP) telemonitoring and pharmacist management intervention in which the interventions stopped after 12 months. There significantly greater reductions systolic BP (SBP) group than usual care at 6, 12, 18 months (−10.7, −9.7, −6.6 mm Hg, respectively). <h3>Objectives</h3> To examine durability effect on through 54 follow-up to compare measurements...
<h3>PURPOSE</h3> The Patient Protection and Affordable Care Act's provisions for first-dollar coverage of evidence-based preventive services have reduced an important barrier to receipt care. Safety-net providers, however, still serve a substantial uninsured population, clinician patient time remain limited in all primary care settings. As consequence, decision makers continue set priorities help focus their efforts. This report updates estimates relative health impact cost-effectiveness...
Evidence indicates that aspirin is effective for the primary prevention of cardiovascular disease (CVD) and colorectal cancer (CRC) but also increases risk gastrointestinal (GI) cerebral hemorrhages.To assess net balance benefits harms from routine use across clinically relevant age, sex, CVD groups.Decision analysis using a microsimulation model.3 systematic evidence reviews.Men women aged 40 to 79 years with 10-year 20% or less, no history without elevated GI hemorrhages would...
OBJECTIVES: We sought to develop and validate a clinical calculator that can be used quantify risk for appendicitis on continuous scale patients with acute abdominal pain. METHODS: The pediatric (pARC) was developed validated through secondary analyses of 3 distinct cohorts. derivation sample included visits 9 emergency departments between March 2009 April 2010. validation single department from 2003 2004 2013 2015. Variables evaluated were as follows: age, sex, temperature, nausea and/or...
Although blood pressure (BP) is routinely measured in outpatient visits, elevated BP and hypertension are often not recognized. We evaluated whether an electronic health record-linked clinical decision support (CDS) tool could improve the recognition management of adolescents.We randomly assigned 20 primary care clinics within integrated system to CDS or usual care. At intervention sites, displayed BPs percentiles, identified incident on basis current previous BPs, offered tailored order...
The US Preventive Services Task Force (USPSTF) is updating its 2016 recommendation on the use of aspirin for primary prevention cardiovascular disease (CVD) and colorectal cancer (CRC).To provide updated model-based estimates net balance in benefits harms from routine low-dose prevention.Microsimulation modeling was used to estimate long-term hypothetical cohorts men women aged 40 79 years with up 20% 10-year risk an atherosclerotic CVD event without prior history or elevated bleeding...
Importance Medication adherence is important for managing blood pressure (BP), low-density lipoprotein cholesterol (LDL-C), and hemoglobin A 1c (HbA ). Interventions to improve medication are needed. Objective To examine the effectiveness of an intervention using algorithmic identification low adherence, clinical decision support physicians, pharmacist outreach patients cardiometabolic BP, LDL-C, HbA control. Design, Setting, Participants 2-arm, patient-randomized, parallel group trial was...
Our aim was to update estimates of the health and economic impact clinical services recommended for primary prevention cardiovascular disease (CVD) comparative rankings National Commission on Prevention Priorities, explore differences in outcomes by sex race/ethnicity.We used a single, integrated, microsimulation model generate comparable results 3 US Preventive Services Task Force: aspirin counseling CVD colorectal cancer, screening treatment lipid disorders (usually high cholesterol),...
<h3>PURPOSE</h3> To help clinicians and care systems determine the priority for tobacco counseling in busy clinic schedules, we assessed lifetime health economic value of annually youth to discourage smoking initiation adults encourage cessation. <h3>METHODS</h3> We conducted a microsimulation analysis estimate impact cost effectiveness both types US birth cohort 4,000,000. The model used was constructed from nationally representative data sets structured literature reviews. <h3>RESULTS</h3>...
Pharmacist-managed (team-based) care for hypertension with home blood pressure monitoring support interventions have been widely studied and shown to be effective in improving rates of control lowering pressure; however, few studies evaluated the economic considerations related bringing these programs into usual practice.To analyze outcomes Blood Pressure Telemonitoring Pharmacist Management on (Hyperlink) study, a cluster randomized controlled trial which used telemonitoring pharmacist case...
Uncontrolled hypertension is a leading contributor to cardiovascular disease. A cluster-randomized trial in 16 primary care clinics showed that 12 months of home blood pressure telemonitoring and pharmacist management lowered more than usual (UC) for 24 months. We report events (nonfatal myocardial infarction, nonfatal stroke, hospitalized heart failure, coronary revascularization, death) costs over 5 years follow-up. In the intervention (TI group, n=228), there were 15 (5 4 1 among 10...
Domestically funded (and performed) research and development (R&D) has historically been a major source of productivity gains in U.S. agriculture, principal R&D spillovers to the rest world. In waning decades 20th century, policymakers opted ratchet down rate growth public support for food agricultural R&D. As 21st century unfolds, slowing given way real cutbacks, reversing accumulation U.S.‐sourced capital over most previous more. The 2014 Farm Bill did little reverse these...
IntroductionTeam-based interventions for hypertension care have been widely studied and shown effective in improving outcomes. Few studies evaluated long-term effects of these interventions; none assessed broad-scale implementation. This study estimates the prospective health, economic, budgetary impact universal adoption a team-based intervention model that targets people with treated but uncontrolled U.S.MethodsAnalysis was conducted 2014−2015 using microsimulation model, constructed...
<h3>Importance</h3> Appendicitis is the most common pediatric surgical emergency. Efforts to improve efficiency and quality of care have increased reliance on computed tomography (CT) ultrasonography (US) in children with suspected appendicitis. <h3>Objective</h3> To evaluate effectiveness an electronic health record–linked clinical decision support intervention, AppyCDS, diagnostic imaging, costs, safety outcomes for patients <h3>Design, Setting, Participants</h3> In this parallel, cluster...
Abstract Background Although shared decision-making (SDM) has knowledge and satisfaction benefits for patients is promising, we lack data demonstrating that SDM associated with better patient-reported functional outcomes. Such would support the integration prioritization of into all aspects orthopaedic care. Questions/purposes (1) Is a measure before total joint arthroplasty outcome measures (PROMs) 1 year postoperatively? (2) What relationship between two patient experience (patient rating...
Based on more recent science spending developments in countries such as China, Korea, India and Brazil, there is a growing sense that the world's scientific deck of cards midst major reshuffle. But it not clear if this reordering limited to just top spenders, or, indeed, how these changes have been playing out over longer term. The new, comprehensive research development (R&D) estimates presented discussed here reveal we are possibly game-changing, albeit partial perhaps irregular, reshuffle...
Blood pressure (BP) is routinely measured in children and adolescents during primary care visits. However, elevated BP or hypertension frequently not diagnosed evaluated further by providers. Barriers to recognition include lack of clinician buy-in, competing priorities, complexity the standard tables.We have developed piloted TeenBP- a web-based, electronic health record (EHR) linked system designed improve prehypertension visits.Important steps developing TeenBP included following: review...
The objective of this study was to assess the potential health and budgetary impacts implementing a pharmacist-involved team-based hypertension management model in United States.In 2017, we evaluated care intervention among 3 targeted groups using microsimulation designed estimate cardiovascular event incidence associated spending cross-section individuals representative US population: it patients with: (1) newly diagnosed hypertension; (2) persistently (≥1 year) uncontrolled blood pressure...