A5066247381- Colorectal Cancer Screening and Detection
- Blood Pressure and Hypertension Studies
- Marriage and Sexual Relationships
- Global Cancer Incidence and Screening
- Gastric Cancer Management and Outcomes
- Health Systems, Economic Evaluations, Quality of Life
- Mycobacterium research and diagnosis
- Diverticular Disease and Complications
- Heart Rate Variability and Autonomic Control
- Primary Care and Health Outcomes
- Cardiovascular Health and Risk Factors
- Health Policy Implementation Science
- Cervical Cancer and HPV Research
- Microscopic Colitis
- Cardiovascular Syncope and Autonomic Disorders
- Healthcare Policy and Management
- Ethics in Clinical Research
- Mobile Health and mHealth Applications
- Genetic factors in colorectal cancer
- Colorectal and Anal Carcinomas
- Cardiac Health and Mental Health
- Economic and Financial Impacts of Cancer
- Pharmaceutical Practices and Patient Outcomes
- Hemodynamic Monitoring and Therapy
- Gastrointestinal disorders and treatments
Kaiser Permanente Washington Health Research Institute
2015-2024
Kaiser Permanente
2017-2024
Colorado Permanente Medical Group
2020-2024
Hawaii Permanente Medical Group
2024
University of Michigan
2014-2023
American College of Preventive Medicine
2014-2023
Association for Prevention Teaching and Research
2018-2023
Washington Center for Equitable Growth
2018-2023
HealthPartners
2021-2022
University of Washington
2011-2022
<h3>Context</h3>Treating hypertension decreases mortality and disability from cardiovascular disease, but most remains inadequately controlled.<h3>Objective</h3>To determine if a new model of care that uses patient Web services, home blood pressure (BP) monitoring, pharmacist-assisted improves BP control.<h3>Design, Setting, Participants</h3>A 3-group randomized controlled trial, the Electronic Communications Home Blood Pressure Monitoring study was based on Chronic Care Model. The trial...
During the COVID-19 pandemic, telemedicine has emerged worldwide as an indispensable resource to improve surveillance of patients, curb spread disease, facilitate timely identification and management ill people, but, most importantly, guarantee continuity care frail patients with multiple chronic diseases. Although during thrived, its adoption moved forward in many countries, important gaps still remain. Major issues be addressed enable large scale implementation include: (1) establishing...
Chinese translation Background: Screening decreases colorectal cancer (CRC) incidence and mortality, yet almost half of age-eligible patients are not screened at recommended intervals. Objective: To determine whether interventions using electronic health records (EHRs), automated mailings, stepped increases in support improve CRC screening adherence over 2 years. Design: 4-group, parallel-design, randomized, controlled comparative effectiveness trial with concealed allocation blinded outcome...
The clinical research enterprise is not producing the evidence decision makers arguably need in a timely and cost effective manner; currently involves use of labor-intensive parallel systems that are separate from care. emergence pragmatic trials (PCTs) poses possible solution: these large-scale embedded within routine care often involve cluster randomization hospitals, clinics, primary providers, etc. Interventions can be implemented by health system personnel through usual communication...
<h3>Importance</h3> Hypertension is a leading cause of cardiovascular disease. The results were previously reported trial home blood pressure (BP) telemonitoring and pharmacist management intervention in which the interventions stopped after 12 months. There significantly greater reductions systolic BP (SBP) group than usual care at 6, 12, 18 months (−10.7, −9.7, −6.6 mm Hg, respectively). <h3>Objectives</h3> To examine durability effect on through 54 follow-up to compare measurements...
<h3>Importance</h3> Approximately 24 million US individuals receive care at federally qualified health centers, which historically have low rates of colorectal cancer screening. The Preventive Services Task Force recommends routine screening for aged 50 to 75 years. <h3>Objective</h3> To determine the effectiveness an electronic record (EHR)-embedded mailed fecal immunochemical test (FIT) outreach program implemented in centers as part standard care. <h3>Design, Setting, and...
Abstract Background: To reduce colorectal cancer mortality, positive fecal blood tests must be followed by colonoscopy. Methods: We identified 62,384 individuals ages 50 to 89 years with a test between January 1, 2011 and December 31, 2012 in four health care systems within the Population-Based Research Optimizing Screening through Personalized Regimens (PROSPR) consortium. estimated probability of follow-up colonoscopy 95% confidence intervals (CI) using Kaplan–Meier method. Overall...
Abstract Uptake of colorectal cancer screening remains suboptimal. Mailed fecal immunochemical testing (FIT) offers promise for increasing rates, but optimal strategies implementation have not been well synthesized. In June 2019, the Centers Disease Control and Prevention convened a meeting subject matter experts stakeholders to answer key questions regarding mailed FIT in United States. Points agreement included: 1) primers, such as texts, telephone calls, printed mailings before FIT,...
The Plan-Do-Study-Act (PDSA) cycle is a commonly used improvement process in health care settings, although its documented use pragmatic clinical research rare. A recent study, called the Strategies and Opportunities to STOP Colon Cancer Priority Populations (STOP CRC), this optimize implementation of an automated colon cancer screening outreach program intervention clinics. We describe using PDSA approach, selection topics by clinic leaders, project leaders' reactions research.STOP CRC...
A team approach is one of the most effective ways to lower blood pressure (BP) in uncontrolled hypertension, but different models for organizing team-based care have not been compared directly.A pragmatic, cluster-randomized trial 2 interventions adult patients with moderately severe hypertension (BP≥150/95 mm Hg): (1) clinic-based using best practices and face-to-face visits physicians medical assistants; (2) telehealth adding home BP telemonitoring home-based coordinated by a clinical...
The receptor for melanin-concentrating hormone (MCH) was recently identified as the orphan G protein-coupled SLC-1. In this study, a CHO cell line expressing MCH (Kd = 1.3 nM; binding capacity, 3.6 pmol/mg protein) is used to assess ability of couple Gi, Go, and Gq proteins. results demonstrate that inhibits forskolin-stimulated cAMP production in pertussis toxin- (PTX)-sensitive manner CHO-MCHR cells (EC50 100 pM), indicating couples one or more members Gi subfamily addition, stimulates...
The national mandate for health systems to transition from ICD-9-CM ICD-10-CM in October 2015 has an impact on research activities. Clinical phenotypes defined by codes need be converted ICD-10-CM, which nearly four times more and a very different structure than ICD-9-CM.We used the Centers Medicare & Medicaid Services (CMS) General Equivalent Maps (GEMs) translate, using methods, condition-specific code sets pragmatic trials (n=32) into ICD-10-CM. We calculated recall, precision, F score of...
The COVID-19 pandemic is a public health crisis, having killed more than 514 000 US adults as of March 2, 2021. mitigation strategies have unintended consequences on managing chronic conditions such hypertension, leading cause cardiovascular disease and disparities in the United States. During first wave States, combination observed racial/ethnic inequities deaths social unrest reinvigorated national conversation about systemic racism care society. 4th Annual University Utah Translational...
Background: Patient-shared electronic health records provide opportunities for care outside of office visits. However, those who might benefit may be unable to or choose not use these resources, while others need them. Objective: Electronic Communications and Home Blood Pressure Monitoring (e-BP) was a randomized trial that demonstrated Web-based pharmacist led improved blood pressure (BP) control. During recruitment we attempted contact all patients with hypertension from 10 clinics...