A5015433082- Birth, Development, and Health
- Blood Pressure and Hypertension Studies
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Pregnancy and preeclampsia studies
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Musculoskeletal pain and rehabilitation
- Heavy Metal Exposure and Toxicity
- Heart Failure Treatment and Management
- Emergency and Acute Care Studies
- Cardiac Arrest and Resuscitation
- Chronic Disease Management Strategies
- Child and Adolescent Health
- Gestational Diabetes Research and Management
- Parathyroid Disorders and Treatments
- Health Policy Implementation Science
- Primary Care and Health Outcomes
- Fatty Acid Research and Health
- Health Systems, Economic Evaluations, Quality of Life
- Cardiovascular Effects of Exercise
- Medication Adherence and Compliance
- Biomedical Text Mining and Ontologies
- Cardiovascular Health and Risk Factors
- Frailty in Older Adults
- Nutrition and Health in Aging
- Genetic Associations and Epidemiology
VA Salt Lake City Healthcare System
2015-2025
University of Utah
2015-2024
George E. Wahlen Department of VA Medical Center
2015-2024
University of Arizona
2023
Southern Arizona VA Health Care System
2023
Arizona State University
2023
Veterans Health Administration
2019
University of Washington
2015
The COVID-19 pandemic is a public health crisis, having killed more than 514 000 US adults as of March 2, 2021. mitigation strategies have unintended consequences on managing chronic conditions such hypertension, leading cause cardiovascular disease and disparities in the United States. During first wave States, combination observed racial/ethnic inequities deaths social unrest reinvigorated national conversation about systemic racism care society. 4th Annual University Utah Translational...
Background Angiotensin II receptor blockers (ARBs) and angiotensin-converting enzyme inhibitors (ACEIs) may positively or negatively impact outcomes in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. We investigated the association of ARB ACEI use with disease 2019 (COVID-19)-related US Veterans treated hypertension using an active comparator design, appropriate covariate adjustment, negative control analyses. Methods findings In this retrospective cohort study Health...
Introduction: The prevalence of blood pressure (BP) control <140/90 mmHg in the Veterans Health Administration (VHA) early 2000s was high (>75%). However, 2017 American College Cardiology (ACC)/American Heart Association (AHA) BP guideline and COVID-19 pandemic may have affected pre-and-post treatment BP. Research Question: Were there changes systolic (SBP, mmHg) relative to guidelines pandemic? Methods: Our retrospective study included initiating antihypertensive medication VHA...
<h3>Objective</h3> Ethnic differences in sudden cardiac arrest resuscitation have not been fully explored and studies yielded inconsistent results. We examined the association of ethnicity with factors affecting outcomes. <h3>Methods</h3> Retrospective cohort study 3551 white, 440 black 297 Asian cases Seattle King County, Washington, USA. <h3>Results</h3> Compared whites, blacks Asians were younger, had lower socioeconomic status more likely to diabetes, hypertension end-stage renal disease...
Little is known regarding fibromyalgia syndrome (FMS) care among Operation Iraqi Freedom/Operation Enduring New Dawn (OIF/OEF/OND) Veterans. Current recommendations include interdisciplinary, team-based combined approaches and limited opioid use. In this study of OIF/OEF/OND Veterans who accessed Health Administration services between 2002 2012, we hypothesized that (defined as at least 4 primary visits/yr with visits to mental health and/or rheumatology) versus <4 only would be associated...
Chronic multisymptom illness (CMI) may be more prevalent among female Operation Enduring Freedom/Operation Iraqi New Dawn (OEF/OIF/OND) deployed Veterans due to deployment-related experiences.To investigate CMI-related diagnoses OEF/OIF/OND Veterans.We estimated the prevalence of International Classification Disease-9th edition-Clinical Modification coded chronic fatigue syndrome, fibromyalgia (FM), and irritable bowel syndrome (IBS) with Health Administration (VHA) visits, FY2002-2012...
Abstract Background Previous reports of associations maternal seafood intake with fetal growth were inconsistent. Further, little is known whether differ across subtypes or indices. Methods Among 3141 participants the Omega study, a pregnancy cohort we investigated periconceptional shell, lean, and fatty fish We categorised food frequency questionnaire reported into frequencies of: <0.2 servings/month, 0.2 servings/month ‐<0.5 servings/week, 0.5–1 >1 servings/week. abstracted...
To investigate associations of maternal periconceptional shellfish, lean fish and fatty intake with risk pregnancy complications.In this prospective cohort study, we collected information on seafood subtypes using FFQ. We categorized into frequencies 1 servings/week. ascertained gestational hypertension, pre-eclampsia, diabetes preterm birth diagnoses from medical records. Using generalized linear models a log link, the Poisson family robust standard errors, estimated ratios 95 % confidence...
<h3>Importance</h3> In December 2013, the panel members appointed to Eighth Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC8) published a recommendation that non-Black adults initiate antihypertensive medication with thiazide-type diuretic, calcium channel blocker, angiotensin-converting enzyme inhibitor (ACEI), or angiotensin receptor blocker (ARB), whereas Black treatment diuretic blocker. β-Blockers were not recommended as...
Background: US guidelines recommend that patients with heart failure reduced ejection fraction (HFrEF), who tolerate an ACEI (angiotensin-converting enzyme inhibitor) or ARB (angiotensin II receptor blocker), be switched to sacubitril/valsartan reduce morbidity and mortality. We compared characteristics healthcare utilization between Veterans HFrEF were versus maintained on ARB. Methods: retrospective cohort study of treated (July 2015–June 2017) using Affairs data. The index date was the...
Background Sacubitril/valsartan, a first-in-class angiotensin receptor neprilysin inhibitor, received US Food and Drug Administration approval in 2015 for heart failure with reduced ejection fraction (HFrEF). Our objective was to describe the sacubitril/valsartan initiation rate, associated characteristics, 6-month follow-up dosing among veterans HFrEF who are renin-angiotensin-aldosterone system inhibitor (RAASi) naïve. Methods Results Retrospective cohort study of RAASi naïve defined as...
Background: Sudden cardiac arrest has been linked independently both to stressful neighborhood conditions and polymorphisms in the ADRB2 gene. The gene mediates sympathetic activation response stress. Therefore, if cause through stress pathway, variant may modify association between conditions, such as socioeconomic deprivation incidence of arrest. Methods: Cardiac Arrest Blood Study Repository is a population-based repository specimens other data from adult patients residing King County,...
Utah's Controlled Substance Database prescription registry does not include master identifiers to link records for individual patients. We describe and evaluate a linkage protocol Database. Prescriptions (N = 22,401,506) dated 2005-2009 were linked using The Link King software patient (e.g. names, dates of birth) 2,232,725 Review 998 randomly selected record pairs classified 46 percent as definitely correct links 54 probably links. A could be confirmed <1 percent. None incorrect or Record...
Background All federal agencies are required to support appropriation requests with evidence and evaluation (US Public Law 115-435; the Evidence Act). The StrAtegic PoLicy EvIdence-Based Evaluation CeNTer (SALIENT) is 1 of 6 centers that help Department Veterans Affairs (VA) meet this requirement. Objective Working existing VA structure, SALIENT evaluations will contribute (1) optimize policies programs for veteran populations; (2) improve outcomes regarding health, equity, cost, provider...
<sec> <title>BACKGROUND</title> All federal agencies are required to support appropriation requests with evidence and evaluation (US Public Law 115-435; the Evidence Act). The StrAtegic PoLicy EvIdence-Based Evaluation CeNTer (SALIENT) is 1 of 6 centers that help Department Veterans Affairs (VA) meet this requirement. </sec> <title>OBJECTIVE</title> Working existing VA structure, SALIENT evaluations will contribute (1) optimize policies programs for veteran populations; (2) improve outcomes...