A5050962927- Probiotics and Fermented Foods
- interferon and immune responses
- Nanoparticle-Based Drug Delivery
- Hydrogels: synthesis, properties, applications
- Gut microbiota and health
- Immunotherapy and Immune Responses
- Antimicrobial Peptides and Activities
- Biochemical and Structural Characterization
- Chronic Kidney Disease and Diabetes
- Advanced Drug Delivery Systems
- GABA and Rice Research
- Rangeland Management and Livestock Ecology
- Nanoplatforms for cancer theranostics
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Language Development and Disorders
- Agriculture Sustainability and Environmental Impact
- Microbial Metabolites in Food Biotechnology
- Reading and Literacy Development
- Infant Nutrition and Health
- Ocular Oncology and Treatments
- RNA Interference and Gene Delivery
- Ferroptosis and cancer prognosis
- Collagen: Extraction and Characterization
- Linguistics and Cultural Studies
- Discourse Analysis and Cultural Communication
Chinese Academy of Agricultural Sciences
2025
Institute of Grassland Research
2025
Jinan University
2011-2024
Southern University of Science and Technology
2022-2024
Southern Medical University
2022-2024
ShenZhen People’s Hospital
2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2022
First Affiliated Hospital of Jinan University
2022
Institute of Psychology, Chinese Academy of Sciences
2020
University of Chinese Academy of Sciences
2020
While Gangba sheep being well known for their unique flavour and nutritional value, harsh environmental factors negatively affect growth development, leading to poor productivity. The gastrointestinal tract microbiota plays an important role in host nutrient absorption metabolism. identification of dynamic changes the microbial communities functions is step towards improving animal production performance health. A comprehensive multi-omics survey was performed under three distinct feeding...
To improve water solubility and bioavailability, curcumin (Cur) was encapsulated by liposomes (Cur-Lip), which further coated with thiolated chitosan (CSSH) to form liposomal hydrogels (CSSH/Cur-Lip gel). The were thermosensitive in situ injectable performance, fluidic at room temperature gelled quickly 37 °C. cumulative release ratio of the 200 μM CSSH/Cur-Lip gel 31.57 ± 1.34% 12 h, could effectively delay curcumin. Worthily, resilient compressive even after five cycles compression....
Diabetic nephropathy (DN) is a severe complication of diabetes, characterized by changes in kidney structure and function. The natural product rosmarinic acid (RA) has demonstrated therapeutic effects, including anti-inflammation anti-oxidative-stress, renal damage or dysfunction. In this study, we the heterogeneity cellular response kidneys to DN-induced injury RA treatment at single cell levels. Our results that significantly alleviated tubular epithelial injury, particularly proximal S1...
The efficacy of treating solid tumors with chemotherapy is primarily hindered by dose-limiting toxicity due to off-target effects and the heterogeneous drug distribution caused dense extracellular matrix. enhanced permeability retention (EPR) effect within restricts circulation diffusion drugs. To overcome these obstacles, hydrogels formed in situ at tumor site have been proposed promote accumulation, retention, long-lasting release. We developed a thiolated chitosan (CSSH) hydrogel gelation...
Aristolochic acids (AAs), a class of carcinogenic and mutagenic natural products from
Abstract Long-term studies have shown that virus infection affects the energy metabolism of host cells, which mainly function mitochondria and leads to hydrolysis ATP in but it is not clear how participates mitochondrial cells. In our study, HUVEC cells were infected with HSV-1, differentially expressed genes obtained by microarray analysis data analysis. The viral gene encoding protein UL16 was identified interact ANT2 immunoprecipitation mass spectrometry. We also reported transfection...
Background Parathyroid carcinoma is an infrequent neoplasm of the endocrine system, constituting roughly 0.5% to 5% cases primary hyperparathyroidism. The diagnosis this condition presents a unique challenge for healthcare professionals. Case report We present case 77-year-old female patient who presented with longstanding right-sided neck tumor. Positron emission tomography-computed tomography (PET-CT) scan detected substantial tumor situated at inferior border thyroid gland. A surgical...
<title>Abstract</title> <bold>Background: </bold>Although there has been some progress in the treatment of primary uveal melanoma (UVM), distant metastasis remains leading cause death patients. Monitoring, staging, and metastatic disease have not yet reached consensus. Although more than half tumors (62%) are diagnosed within five years after tumor treatment, remainder only detected following 25 years. The mechanisms UVM its impact on prognosis fully understood. <bold>Methods:</bold>...
Reducing prediction delay for streaming end-to-end ASR models with minimal performance regression is a challenging problem. Constrained alignment well-known existing approach that penalizes predicted word boundaries using external low-latency acoustic models. On the contrary, recently proposed FastEmit sequence-level regularization scheme encouraging vocabulary tokens over blanks without any reference alignments. Although all these schemes are successful in reducing delay, error rate (WER)...
One of the major causes immunotherapy resistance is loss histocompatibility complex class I (MHC-I) molecules in tumor cells or downregulation antigen presentation pathway. In this study, a novel virus-like nanotherapeutic (siRNA@HCM) developed via encapsulating nanosized siRNA nanoparticles hybrid membrane comprising personalized cell and universal 293T expressing mutant vesicular stomatitis virus glycoprotein (mVSV-G). Upon intravenous administration, siRNA@HCM accumulates at site provides...
The chronic enteritis disease ulcerative colitis (UC) is a formidable opponent, and its etiology remains unclear. Current studies have shown that oxidative stress closely related to the pathogenesis of inflammatory bowel disease. Antioxidant enzymes, such as manganese superoxide dismutase (MnSOD)，have been deemed exert an anti-inflammatory function. Normally, oral administration MnSOD directly leads incapacitation because poor penetration stability. To address this problem, probiotic
With the increasing incidence and mortality of renal cancer, it is pressing to find new biomarkers drug targets for diagnosis treatment. However, as one negative upstream regulator p53, prognostic immunological role NFE2L3 in cancer still barely known. We investigated expression, value, relevant pathways using datasets from public databases, including The Cancer Genome Atlas Program (TCGA), Genotype-Tissue Expression (GTEx), Cell Line Encyclopedia (CCLE), UALCAN. Furthermore, we analyzed...