John R. Duffy

ORCID: 0000-0003-3548-2313
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About
Contact & Profiles
Research Areas
  • Mental Health Research Topics
  • Functional Brain Connectivity Studies
  • Psychometric Methodologies and Testing
  • Health, Environment, Cognitive Aging
  • Cognitive Abilities and Testing
  • Stroke Rehabilitation and Recovery
  • Child and Adolescent Psychosocial and Emotional Development
  • Advanced materials and composites
  • Air Quality and Health Impacts
  • Resilience and Mental Health
  • Brain Tumor Detection and Classification
  • Advanced Statistical Modeling Techniques
  • Mindfulness and Compassion Interventions
  • High Altitude and Hypoxia
  • Neural and Behavioral Psychology Studies
  • Fibromyalgia and Chronic Fatigue Syndrome Research
  • Neuroscience of respiration and sleep
  • Schizophrenia research and treatment
  • Thermal Regulation in Medicine
  • Agriculture and Farm Safety
  • Cardiac Arrest and Resuscitation
  • Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
  • Powder Metallurgy Techniques and Materials
  • Vietnamese History and Culture Studies
  • Posttraumatic Stress Disorder Research

Syrentis Clinical Research
2024

Colorado State University
2020-2024

University of Pennsylvania
1959

The results of analysis edema fluid and excised lungs show that there is leakage protein-rich into the lung tissue ultimately respiratory passages. This cannot be explained by reduction in oxygen uptake as observed slices. ultimate cause pulmonary not known. survival time anesthetized dogs suffering from thermal edema, can prolonged inhalation administration antihistaminic drugs vasodilators.

10.1161/01.res.7.6.1018 article EN Circulation Research 1959-11-01

Cognitive tasks are used to probe neuronal activity during functional magnetic resonance imaging (fMRI) detect signs of aberrant cognitive functioning in patients diagnosed with schizophrenia (SZ). However, nonlinear (inverted-U-shaped) associations between and task difficulty can lead misinterpretation group differences healthy comparison subjects (HCs). In this paper, we evaluated a novel method for correcting these misinterpretations based on conditional performance analysis.Participants...

10.1017/s1355617721000424 article EN cc-by Journal of the International Neuropsychological Society 2021-05-05

Background: To date, no one has prospectively evaluated yoga intervention-induced changes in brain structure or function adults with acquired injuries (ABI). Thus, this study was conducted to test the feasibility of acquiring neuroimaging data from ABI before and after a intervention. Methods: This single-arm intervention that included 12 chronic (i.e., greater than 6 months post-injury) self-reported limitations balance. Neuroimaging were yoga. The completed once per week for eight weeks....

10.3390/brainsci13101413 article EN cc-by Brain Sciences 2023-10-05

The adaptation of experimental cognitive tasks into measures that can be used to quantify neurocognitive outcomes in translational studies and clinical trials has become a key component the strategy address psychiatric neurological disorders. Unfortunately, while most tests have strong theoretical bases, they poor psychometric properties, leaving them vulnerable measurement challenges undermine their use applied settings. Item response theory–based computerized adaptive testing been proposed...

10.1177/0013164420919898 article EN Educational and Psychological Measurement 2020-06-02

The NIMH Research Domain Criteria (RDoC) initiative seeks to utilize multidimensional patterns of socio-cognitive behavior improve understanding mental illness. We aimed evaluate the psychometric properties a subset RDoC tasks. Specifically, we investigated two positive valence tasks and five cognitive Participants (

10.1177/10731911241280770 article EN Assessment 2024-10-06

Abstract INTRODUCTION Diagnostic assessments of mild cognitive impairment (MCI) are lengthy and burdensome, highlighting the need for new tools to detect MCI. Time-domain functional near-infrared spectroscopy (TD-fNIRS) can measure brain function in clinical settings may address this need. METHODS MCI patients (n=50) age-matched healthy controls (HC; n=51) underwent TD-fNIRS recordings during tasks (verbal fluency, N-back). Machine learning models were trained distinguish from HC using...

10.1101/2024.11.06.24316775 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2024-11-07

Objective: Agricultural workers are immersed in environments associated with increased risk for adverse psychiatric and neurological outcomes. work-related risks to brain health include exposure pesticides, heavy metals, organic dust. Despite this, there is a gap our understanding of the underlying systems impacted by these risks. This study explores clinical cognitive domains, functional activity agricultural workers. We hypothesized that history would be poorer outcomes as well changes...

10.1017/s1355617723011098 article EN Journal of the International Neuropsychological Society 2023-11-01

Objective: Deficits in cognitive ability are common among patients with schizophrenia. The MATRICS Consensus Cognitive Battery (MCCB) was designed to assess studies of diagnosed schizophrenia and has demonstrated high test-retest reliability minimal practice effects, even multi-site trials. However, given the motivational challenges associated schizophrenia, it is unknown whether performance on MCCB tasks affects at later stages testing. goal this study determine there differences between...

10.1017/s1355617723010561 article EN Journal of the International Neuropsychological Society 2023-11-01

Objective: Cognitive deficits in patients diagnosed with schizophrenia are a core feature of the disorder. There currently no treatments for these cognitive deficits. Our aim was to examine and compare patterns increased versus decreased activity central executive network (CEN), salience (SN), default mode (DMN) between healthy controls (HCs) (SZs) as well explore influence task load on networks HCs SZs. Participants Methods: Analyses focused secondary dataset comprising Blood Oxygen-Level...

10.1017/s1355617723011359 article EN Journal of the International Neuropsychological Society 2023-11-01

Objective: As part of the Research Domain Criteria (RDoC) initiative, NIMH seeks to improve experimental measures cognitive and positive valence systems for use in intervention research. However, many RDoC tasks have not been psychometrically evaluated as a battery measures. Our aim was examine factor structure 7 such chosen their relevance schizophrenia other forms serious mental illness. These include n-back, Sternberg, self-ordered pointing (measures working memory construct); flanker...

10.1017/s1355617723008731 article EN Journal of the International Neuropsychological Society 2023-11-01

Isostatic pressing has several benefits over the commonly used press and sinter method, including equal compaction in all directions a more uniform final component density. Nevertheless, as with other powder metallurgy processes, manufacturers must carefully characterize metal powder’s properties for process to be successful. Commonly characterized physical include flow, density, hardness, particle size, shape of respective powders.Other key characteristics chemistry microstructure....

10.59499/wp225372178 article EN 2022-09-15
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