Sophia Themistocleous

ORCID: 0000-0003-3561-0004
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About
Contact & Profiles
Research Areas
  • Ethics in Clinical Research
  • Vaccine Coverage and Hesitancy
  • COVID-19 and Mental Health
  • Misinformation and Its Impacts
  • Cancer Research and Treatments
  • Healthcare professionals’ stress and burnout
  • Data-Driven Disease Surveillance
  • Gut microbiota and health
  • Innovations in Medical Education
  • Global Health and Surgery
  • COVID-19 and healthcare impacts
  • Adrenal Hormones and Disorders
  • Breast Lesions and Carcinomas
  • Artificial Intelligence in Healthcare and Education
  • HER2/EGFR in Cancer Research
  • PI3K/AKT/mTOR signaling in cancer
  • Endoplasmic Reticulum Stress and Disease
  • SARS-CoV-2 detection and testing
  • Ion Transport and Channel Regulation
  • CRISPR and Genetic Engineering
  • Mitochondrial Function and Pathology
  • AI in cancer detection
  • Cancer-related gene regulation
  • Zoonotic diseases and public health
  • Hormonal Regulation and Hypertension

European University Cyprus
2019-2025

University of Cyprus
2022

The coronavirus disease 2019 (COVID-19) pandemic has evidenced the key role of vaccine design, obtention, production and administration to successfully fight against infectious diseases provide efficient remedies for citizens. Although clinical trials were rapidly established during this pandemic, identifying suitable study subjects can be challenging. For reason, University Hospital Cologne a volunteer registry participation in first Germany, which now been incorporated into European...

10.1016/j.vaccine.2022.05.022 article EN cc-by Vaccine 2022-06-02

Data standards are not only key to making data processing efficient but also fundamental ensuring interoperability. When clinical trial structured according international standards, they become significantly easier analyze, reducing the efforts required for cleaning, preprocessing, and secondary use. A common language a shared set of expectations facilitate interoperability between systems devices. The main objectives this study were identify commonalities differences in metadata, protocols,...

10.2196/65590 article EN cc-by JMIR Medical Informatics 2025-03-07

The Covid-19 pandemic disrupted medical education, shifting it towards emergency remote delivery. This cross-sectional study aimed to assess the impact of on preclinical education and identify predictors virtual learning experience perceived stress. An anonymous survey was delivered electronically students authors' school that attended either histology or pathology. contained two scales, (VLE) stress scale-10 (PSS-10). A total 173/255 (68%) responded, showing a positive perception delivery...

10.1002/ase.2159 article EN Anatomical Sciences Education 2021-12-02

Aim To investigate medical students’ burnout and motivation levels in each of the six years their studies during COVID-19 pandemic identify independent predictors motivation. Methods An anonymous cross-sectional survey was sent to students all within our school. Burnout measured with adapted Oldenburg Inventory questionnaire (OLBI-S) updated Strength Motivation for Medical School (SMMS-R) questionnaire. Univariate analysis performed Kruskal–Wallis test Spearman’s correlation, while...

10.3389/fmed.2023.1214320 article EN cc-by Frontiers in Medicine 2023-08-28

Background The pan-European VACCELERATE network aims to implement the first transnational harmonized and sustainable vaccine trial Volunteer Registry, being a single entry point for potential volunteers of large-scale trials across Europe. This work exhibits set trial–related educational promotional tools general public, designed disseminated by network. Objective study primarily aimed design develop standard toolkit increase positive attitudes access trustworthy information better increased...

10.2196/44491 article EN cc-by JMIR Public Health and Surveillance 2023-03-07

Background The VACCELERATE Pan-European Scientific network aims to strengthen the foundation of vaccine trial research across Europe by following principles equity, inclusion, and diversity. Volunteer Registry provides access sites European region supports a sustainable volunteer platform for identifying potential participants forthcoming clinical research. Objective aim this study was approach members patient advocacy groups (PAGs) assess their willingness register perspectives related...

10.2196/47241 article EN JMIR Public Health and Surveillance 2024-04-04

This comprehensive review elucidates the profound relationship between human microbiome and breast cancer managrement. Recent findings highlight significance of microbial alterations in tissues, such as gut breast, their role influencing risk, development, progression, treatment outcomes. We delve into how can modulate systemic inflammatory responses estrogen levels, thereby impacting initiation therapeutic drug efficacy. Furthermore, we explore unique diversity within tissue, indicating...

10.20944/preprints202311.0745.v1 preprint EN 2023-11-13

Underserved and hard-to-reach population groups are under-represented in vaccine trials. Thus, we aimed to identify the challenges of trial participation these member countries VACCELERATE network. Seventeen National Coordinators (NC), each representing their respective country (15 European countries, Israel, Turkey), completed an online survey. From 15 eligible groups, those that were more frequently declared underserved/hard-to-reach research ethnic minorities (76.5%), persons experiencing...

10.3390/vaccines11121784 article EN cc-by Vaccines 2023-11-29

<sec> <title>BACKGROUND</title> Data standards are not only key to making data processing efficient but also fundamental ensuring interoperability. When clinical trial structured according international standards, they become significantly easier analyze, reducing the efforts required for cleaning, preprocessing, and secondary use. A common language a shared set of expectations facilitate interoperability between systems devices. </sec> <title>OBJECTIVE</title> The main objectives this study...

10.2196/preprints.65590 preprint EN 2024-08-21

<sec> <title>BACKGROUND</title> The VACCELERATE Pan-European Scientific network aims to strengthen the foundation of vaccine trial research across Europe by following principles equity, inclusion, and diversity. Volunteer Registry provides access sites European region supports a sustainable volunteer platform for identifying potential participants forthcoming clinical research. </sec> <title>OBJECTIVE</title> aim this study was approach members patient advocacy groups (PAGs) assess their...

10.2196/preprints.47241 preprint EN 2023-03-15

<sec> <title>BACKGROUND</title> The pan-European VACCELERATE network aims to implement the first transnational harmonized and sustainable vaccine trial Volunteer Registry, being a single entry point for potential volunteers of large-scale trials across Europe. This work exhibits set trial–related educational promotional tools general public, designed disseminated by network. </sec> <title>OBJECTIVE</title> study primarily aimed design develop standard toolkit increase positive attitudes...

10.2196/preprints.44491 preprint EN 2022-11-21
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