A5071923107- T-cell and Retrovirus Studies
- Multiple Myeloma Research and Treatments
- Animal Disease Management and Epidemiology
- Iron Metabolism and Disorders
- Vector-Borne Animal Diseases
- COVID-19 Clinical Research Studies
- Peptidase Inhibition and Analysis
- Hemoglobinopathies and Related Disorders
- Blood donation and transfusion practices
- Chronic Lymphocytic Leukemia Research
- Cancer, Hypoxia, and Metabolism
- Lung Cancer Treatments and Mutations
- Hematological disorders and diagnostics
- Acute Myeloid Leukemia Research
- Atrial Fibrillation Management and Outcomes
- Protein Degradation and Inhibitors
- Lymphoma Diagnosis and Treatment
- Venous Thromboembolism Diagnosis and Management
Instituto de Investigación Médica Mercedes y Martín Ferreyra
2016-2023
The University of Texas MD Anderson Cancer Center
2021
PURPOSE Adult T-cell leukemia/lymphoma (ATLL) is an aggressive disease caused by the human leukemia virus type 1. Real-world data of ATLL in Latin America are lacking. PATIENTS AND METHODS We analyzed patients with (acute, lymphomatous, chronic, and smoldering) encountered 11 American countries between 1995 2019. Treatment response was assessed according to 2009 consensus report. Survival curves were estimated using Kaplan-Meier method log-rank test. RESULTS identified 253 patients; 226...
Different pivotal works allowed the approval of ibrutinib as a CLL treatment, both in first line and relapsed/refractory patients, adverse effects differ from conventional chemotherapy, discontinuation rate was 10%, but different real-life studies, showed higher number complications medication suspension rates 40 to 50%. To know reality use our environment, we designed this work with objectives evaluating safety profile drug description effects, their incidence, severity. The clinical...
Background: Peripheral blood (PB) is an accessible tissue to study the traffic of all types and subsets cells. The frequency PB involvement depends on sensitivity methods used. Next Generation Flow (NGF)‐MM MRD Euroflow workflow provides a high specific, sensitive applicable method detect plasma cells in multiple myeloma (MM) patients after therapy. This Standard Operation Procedure (SOP) can be used increase sensibility circulating detection. Taking this into account, we investigated number...
Las alteraciones citogenéticas (AC) constituyen uno de los factores pronósticos más importantes en pacientes con mieloma múltiple (MM) permitiendo dividirlos dos grupos riesgo (estándar y alto) diferente pronóstico enfoque terapéutico. Actualmente las AC que tienen mayor relevancia para la estratificación MM son: el índice ploidía, rearreglos del gen IGH, inactivación TP53 cromosoma 1 (deleción 1p y/o ganancias 1q). La técnica elección detección MM, tanto al momento diagnóstico como...
PET CT adapted treatment for first line Hodgkin Lymphoma has been widely studied in the last decades. Long-term follow-up is important to judge both efficacy and safety of this approach. Patients Methods: We analyzed updated data on all patients (pts.) treated within LH-05 GATLA trial. Newly diagnosed pts. with HL Stages I-IV were included. All received 3 ABVD evaluated a PET-CT (PET-CT+3). Pts. negative PET-CT+3 (DS 1 2) considered metabolic CR no further therapy. Pts DS 4 completed 6 IFRT...