A5061612336- T-cell and Retrovirus Studies
- Lymphoma Diagnosis and Treatment
- Vector-Borne Animal Diseases
- Animal Disease Management and Epidemiology
- Viral-associated cancers and disorders
- Chronic Lymphocytic Leukemia Research
- Multiple Myeloma Research and Treatments
- Acute Lymphoblastic Leukemia research
- Acute Myeloid Leukemia Research
- Colorectal and Anal Carcinomas
- Gastrointestinal Tumor Research and Treatment
- COVID-19 Clinical Research Studies
- COVID-19 and healthcare impacts
- Leprosy Research and Treatment
- Protease and Inhibitor Mechanisms
- Chemotherapy-related skin toxicity
- Heme Oxygenase-1 and Carbon Monoxide
- Pain Management and Treatment
- Migraine and Headache Studies
- Rural Development and Agriculture
- Maternal and Neonatal Healthcare
- Polyomavirus and related diseases
- Chronic Myeloid Leukemia Treatments
- Environmental and biological studies
- Cutaneous lymphoproliferative disorders research
Faculdade de Medicina do ABC
2011-2024
Hospital Estadual Mário Covas
2022-2023
D’Or Institute for Research and Education
2023
Insper
2023
Universidade Federal de São Paulo
1998-2016
National Blood Transfusion Service
2003
Among the 2016 Olympic and Paralympic Games unforgettable moments, one could not overlook performances by Phelps Bolt, which challenge old premises about maximum extension of individual supremacism in ultracompetitive modalities doping scandals. Different media channels resonated these two trends, with an unseen rise on discussions traits practices that may set ultrahigh performance athletes apart from more ordinary ones. Yet, some key issues remain undebated. This paper aims to add this...
We describe 195 cases of adult T-cell leukemia/lymphoma (ATLL) reported to the national registry malignancies in Brazil between 1994 and 1998. compared effect demographic differences clinical features 150 consecutive ATLL different regions this diverse country. At diagnosis, predominant sub-type was acute type (60%), followed by lymphoma (22%), chronic (10%) smoldering (8%) types. Although we expected that sub-types would be present regions, on basis immunogenetic factors determined...
We studied the transmission routes of human T-cell lymphotropic virus type I (HTLV-I) within families 82 Brazilian patients diagnosed with adult leukaemia/lymphoma (ATL). Diagnosis ATL in 43 male and 39 female was based on clinical laboratory criteria malignancy detection HTLV-I monoclonal integration. Samples were tested for HTLV antibodies infection confirmed as by Western Blot and/or polymerase chain reaction (PCR) assays. Overall 26/37 (70%) mothers, 24/37 (65%) wives, 8/22 (36%)...
Abstract The COVID‐19 pandemic has had a crucial impact on lifestyle worldwide. In this way, many studies have been presented, leading to continuous revaluation and questioning of conducts concepts. Such is the case Chinese study suggesting that new coronavirus potential code anomalous nonstructural proteins capable dissociating iron atom from porphyrin structure, contributing significantly characteristic hypoxemia conditions disease. Considering impacts those findings, current aims evaluate...
We reported seven cases (0.7%) of PTLD among 1002 renal transplants performed at Renal Transplant Service from Hospital Sao Paulo - Universidade Federal de Paulo/Escola Paulista Medicina, Paulo, Brazil, between 1976 and 1997. There were three male four female patients with median age 37 year-old. According to Ann Arbor staging system there localized extra-nodal intermediate-grade NHL, one disseminated low-grade NHL two polyclonal lymphoid hyperplasia. Four received cadaveric, related...
Objective: To present a descriptive analysis of patients diagnosed with multiple myeloma, correlating it mortality. Methods: A retrospective study that analyzed consecutive myeloma under follow-up at the Faculdade de Medicina do ABC from 2006 to 2010. Results: The median age was 58.5 years. Anemia observed upon diagnosis in 87% patients, hypercalcemia 38%, and creatinine levels higher than 2 mg/dL 19%. M protein detected 85.7%. five-year survival rate 74.6%. Multivariate showed statistical...
Duodenal-type follicular lymphoma (DFL) is a rare subtype classified by the 5th edition of WHO and international consensus classifications lymphoid neoplasms, typically presenting as localized disease with favorable outcomes. This multicenter retrospective study examines 53 Brazilian DFL patients median age 58.2 years (33-85), males comprising 50% (
We examined the presence of HTLV-I infection among 66 family members 13 patients with well documented ATL to investigate routes HLTV-I transmission in a Southeast region Brazil was screened by an enzyme immunossay (ELISA) test and all repeatedly positive or indeterminate ELISA samples were further tested Western-Blot (WB) technique. Indeterminate inconclusive WB confirmed polymerase chain reaction (PCR). results showed that 40 (60.6%) individuals not infected; 16 (24.2%) positive; 10 (15.2%)...
Introdução: Apesar do excelente prognóstico linfoma de Hodgkin, 20 a 25% dos pacientes são refratários primários e cerca 30% deles recaem requerem tratamento complementar. A estratégia resgate inclui esquemas mais agressivos quimioterapia, radioterapia transplante células tronco-hematopoiéticas. Objetivo: Descrever experiência da Faculdade Medicina ABC (FMABC) no com Hodgkin que foram submetidos autólogo medula óssea como parte resgate. Métodos: Estudo retrospectivo descritivo foi realizado...
Introduction: Duodenal-type follicular lymphoma (DFL) is a rare entity, presented mostly as localized disease and excellent long-term outcomes. Its pathogenesis peculiar predilection for the duodenum not clear. Wide use of endoscopy several reasons seems to highlight this increase its diagnosis, since many patients are asymptomatic. Environment aspects, such diet local infections, could play role in clinical presentation evolution. Methods: We evaluated 53 with diagnosis DFL based on current...
Introduction: Adult T-cell leukemia/lymphoma (ATL) is a peripheral malignancy caused by human leukemia virus type I (HTLV-1), endemic in some areas of the world, such as Brazil. Between 3% and 5% HTLV-1-infected individuals develop ATL after long latency. The clinical features are heterogeneous classified into acute, lymphoma, chronic smoldering types. Acute lymphoma types defined aggressive whereas others indolent ATL. On April 2017, Brazil project was launched. Methods: Ambispective...
Topic: 19. Aggressive Non-Hodgkin lymphoma - Clinical Background: In western countries, non-Hodgkin’s lymphomas of peripheral T-cells (PTCL) represent about 12% all NHL. Brazil, the National Institute Cancer (INCA) estimates for years 2023/2024/2025 12,040 new cases NHL, which would result in a just over 1,444 T-cell NHL peripheral. Brazil project is study to collect data from five macro regions period January 2015 December 2022. Aims: The main goal epidemiological and clinical most frequent...
In Brazil, the National Institute of Cancer estimates for years 2023-2025 about 12,040 new cases NHL, 1,444 peripheral T-cell lymphomas (PTCLs). Brazil project is an ambispective study inserting diagnosis from January 2015 to December 2022. Our goal was explore a prospective cohort (PC), April 2017-December 2022, analyzing primary refractory and relapse (R/R) PTCLs pts bad factors overall survival (OS). PC enrolled 461 who received 1ª treatment line. Descriptive analyses, Kaplan-Meier...
T-cell Brazil project started in April 2017 focusing to collecting epidemiological and clinical data from the most frequent subtypes of PTCL, as an ambispective study collected diagnosis January 2015 December 2022. Our goals were obtain frequency biology characteristic five Brazilian regions; besides have a routine pathological revision evaluate Overall Survival (OS), Progression-Free (PFS) 5 years follow-up. After 39 centers approved by their Ethical Committee, they registered cases using...
To evaluate number of extranodal (EN) sites in nodal PTCL lymphomas (PTCL-NOS, TFH and ALCL ALK+/ALK-) its specific location as a surrogate for overall survival (OS) progression free (PFS). Also generate hypothesis further molecular analysis. T-cell Brazil project is national, ambispective study patients (pts) with histological diagnosis diagnosed from January 2015 to December 2022. Approval the was obtained at coordinating center (Samaritano Hospital – São Paulo) each participating center....