A5100632126- Rheumatoid Arthritis Research and Therapies
- Spondyloarthritis Studies and Treatments
- Systemic Lupus Erythematosus Research
- Autoimmune and Inflammatory Disorders Research
- Monoclonal and Polyclonal Antibodies Research
- Systemic Sclerosis and Related Diseases
- Lymphoma Diagnosis and Treatment
- Chronic Lymphocytic Leukemia Research
- Bone health and osteoporosis research
- Bone and Joint Diseases
- Biosimilars and Bioanalytical Methods
- Immunodeficiency and Autoimmune Disorders
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Complement system in diseases
- Pituitary Gland Disorders and Treatments
- Blood groups and transfusion
- Autoimmune Bullous Skin Diseases
- Vitamin D Research Studies
- Atherosclerosis and Cardiovascular Diseases
- T-cell and B-cell Immunology
- Psoriasis: Treatment and Pathogenesis
- Nerve Injury and Rehabilitation
- Peripheral Nerve Disorders
- Artificial Intelligence in Healthcare and Education
Universidade Federal de São Paulo
2023-2024
Hospital Sírio-Libanês
2023-2024
Hospital de São João
2007-2018
Center for Rheumatology
2013-2014
Universidade do Porto
2007
Instituto Português de Oncologia Francisco Gentil
2004
Instituto Português de Oncologia de Coimbra Francisco Gentil
2004
BACKGROUND: Hyperplastic polyposis (HP) is a rare condition characterized by the presence of multiple hyperplastic polyps in colon, which has been associated to an increased risk colorectal cancer (CRC). Guidelines for management this disease remain, so far, undefined. AIMS: To evaluate, symptomatic patients with HP, phenotypic characteristics as well results screening program their at-risk first-degree relatives. PATIENTS Pedigree information and clinical endoscopic data 14 HP was studied....
Objective To evaluate whether use of comedication with conventional synthetic disease‐modifying antirheumatic drugs (csDMARDs) influences the retention tumor necrosis factor inhibitors (TNFi) in patients spondyloarthritis (SpA). Methods Patients SpA from Rheumatic Diseases Portuguese Register who started treatment their first TNFi between 2001 and 2014 were included this study. Cox regression analysis was used to estimate effect csDMARDs on 2 types models: a model which baseline (time‐fixed)...
<h3>Background</h3> Vitamin D has been shown to have significant immunomodulatory effects. Its actions are mediated by the ubiquitous vitamin receptor (VDR). In one study, BsmI VDR gene polymorphism was associated with an early onset of rheumatoid arthritis (RA). Additionally, TT genotype FokI established as a genetic susceptibility marker for RA in French and Tunisian populations. <h3>Objectives</h3> To determine degree association polymorphisms disease activity patients RA....
Duodenal-type follicular lymphoma (DFL) is a rare subtype classified by the 5th edition of WHO and international consensus classifications lymphoid neoplasms, typically presenting as localized disease with favorable outcomes. This multicenter retrospective study examines 53 Brazilian DFL patients median age 58.2 years (33-85), males comprising 50% (
A insuficiência cardíaca crônica (ICC) é uma condição complexa e progressiva, caracterizada por redução na capacidade do coração de bombear sangue forma eficaz. Nos últimos anos, houve avanços substanciais no tratamento da ICC, especialmente com fração ejeção reduzida (ICFER). O uso medicamentos como betabloqueadores, inibidores neprilisina dos receptores angiotensina (ARNIs), antagonistas receptor mineralocorticoide (ARM) SGLT-2 tem demonstrado reduzir significativamente a mortalidade as...
<h3>Background</h3> Anti-SSa/Ro antibodies are among the common found in Systemic Sclerosis (SSc) patients (prevalence range 15–38%). Recent studies have suggested association of anti-SSa/Ro with interstitial lung disease (ILD) as well their prognostic role SSc patients, however its definitive importance is yet to be determined. <h3>Objectives</h3> To determine prevalence a cohort and clinical serological features. <h3>Methods</h3> Observational retrospective study was performed including...
Introduction Paroxysmal nocturnal hemoglobinuria (PNH) is a clonal disease of hematopoietic cells with variable clinical spectrum characterized by intravascular hemolysis, high risk thrombosis, and cytopenias. To understand the biochemical shifts underlying PNH, this study aimed to search for dysfunctional pathways involved in PNH physiopathology comparing systemic metabolic profiles affected patients healthy controls metabolomic before after administration eculizumab undergoing treatment....
<h3>Background</h3> Low bone mineral density (BMD) is highly prevalent in patients with systemic lupus erythematosus (SLE). However, determinants of BMD changes SLE are still largely unknown. <h3>Objectives</h3> The aim this study was to describe the clinical characteristics submitted a dual energy X-ray absorptiometry (DEXA), evaluating prevalence osteopenia/osteoporosis and searching for possible predictors loss these patients. <h3>Methods</h3> Retrospective observational 160 our...
<h3>Background</h3> The induction of auto-antibodies, such as anti-nuclear antibodies (ANA), is a well-known phenomenon during anti-TNF alpha treatment. However, the correlation this increase in ANA production and clinical response to anti-TNFα Spondyloarthritis (Spa) patients not yet determined. <h3>Objectives</h3> To determine impact positivity for (at baseline after treatment) persistency treatment Spa patients. <h3>Methods</h3> Observational retrospective cohort study was performed....
Searchable abstracts of presentations at key conferences on calcified tissues ISSN 2052-1219 (online)
<h3>Background</h3> Intravenous immunoglobulin (IVIG) is effective in a wide range of clinical conditions, other than primary immunodeficiency, including rheumatic diseases. In fact, the era newer immunosuppressive drugs, there has been an over-increasing number indications for which IVIG tried with success. <h3>Objectives</h3> To evaluate effectiveness and adverse events off-label treatment different diseases, patients our Rheumatology Department. <h3>Methods</h3> We performed observational...
<h3>Background</h3> The involvement of the enthesis in patients with spondyloarthritis (SpA) can be a factor disability. efficacy TNF antagonists on SpA activity is well established and similar between all drugs available at moment. On other hand, anti-TNF treatment enthesitis not as well-known doesn9t seem strong its effect overall disease activity. <h3>Objectives</h3> To analyze effectiveness SpA. <h3>Methods</h3> A retrospective analysis that started or switched rheumatology department...
<h3>Background</h3> Enthesitis is a common and well described condition in spondylarthropathies. Currently several scores attempt to cover all affected areas practical way so that allows reproducible assessment. <h3>Objectives</h3> To evaluate whether there correlation between the of entheses (SPARCC MASES) clinical laboratory parameters patients with ankylosing spondylitis (AS) psoriatic arthritis (PsA). <h3>Methods</h3> We made retrospective analysis (July/2012 December/2013) AS PsA under...