Guilherme Duffles

ORCID: 0000-0002-6058-7558
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Lymphoma Diagnosis and Treatment
  • Chronic Lymphocytic Leukemia Research
  • Chronic Myeloid Leukemia Treatments
  • T-cell and Retrovirus Studies
  • CNS Lymphoma Diagnosis and Treatment
  • CAR-T cell therapy research
  • Viral-associated cancers and disorders
  • Acute Myeloid Leukemia Research
  • Cancer Genomics and Diagnostics
  • Gastrointestinal Tumor Research and Treatment
  • Vascular Tumors and Angiosarcomas
  • Eosinophilic Disorders and Syndromes
  • Salivary Gland Disorders and Functions
  • Acute Lymphoblastic Leukemia research
  • Lung Cancer Treatments and Mutations
  • Histone Deacetylase Inhibitors Research
  • Women's cancer prevention and management
  • Synthesis of Tetrazole Derivatives
  • BRCA gene mutations in cancer
  • Genetic factors in colorectal cancer
  • Multiple Myeloma Research and Treatments
  • Graphene and Nanomaterials Applications
  • Public Health in Brazil
  • Parkinson's Disease and Spinal Disorders
  • Cutaneous lymphoproliferative disorders research

Universidade Estadual de Campinas (UNICAMP)
2021-2025

D’Or Institute for Research and Education
2020-2023

SPX Corporation (United States)
2022

Instituto do Câncer do Estado de São Paulo
2019-2021

Universidade de São Paulo
2019-2020

Hospital Sírio-Libanês
2019

Palmetto Hematology Oncology
2019

University of Rijeka
2019

Managing chronic myeloid leukemia during pregnancy presents significant challenges, with limited treatment options available depending on the stage of pregnancy. All existing tyrosine kinase inhibitors are considered teratogenic, especially first trimester and should be avoided. In this case report, we detail successful, unplanned dichorionic diamniotic twin a patient chronic-phase previously resistant to imatinib dasatinib who was exposed allosteric inhibitor asciminib early weeks...

10.1007/s00277-025-06238-9 article EN cc-by-nc-nd Annals of Hematology 2025-03-08

10.1016/j.htct.2025.103745 article EN Hematology Transfusion and Cell Therapy 2025-03-06

Abstract Sjogren’s disease (SjD) is an autoimmune that characterized not only by the sicca symptoms it causes but also its systemic nature, which capable of several and yet fully understood extraglandular manifestations. To gain a clearer understanding these manifestations as well better practical approach, panel experts from Brazilian Society Rheumatology conducted systematic review meta-analysis on identification epidemiologic clinical features present in ESSDAI (EULAR Sjogren´s syndrome...

10.1186/s42358-024-00391-x article EN cc-by Advances in Rheumatology 2024-07-09

Tyrosine kinase inhibitors (TKI) have revolutionized the treatment of patients with chronic myeloid leukemia. Patients who achieve sustained deep molecular response are eligible for discontinuation. DES-CML is an ongoing, phase 2 multicentric discontinuation trial. Adult CML in typical BCR::ABL1 transcripts, stable (MR4.5 IS) two years, and no previous resistance were eligible. underwent a TKI dose de-escalation six months before was reintroduced at if patient lost major (MMR) any time. This...

10.3389/fonc.2024.1393191 article EN cc-by Frontiers in Oncology 2024-05-08

Duodenal-type follicular lymphoma (DFL) is a rare subtype classified by the 5th edition of WHO and international consensus classifications lymphoid neoplasms, typically presenting as localized disease with favorable outcomes. This multicenter retrospective study examines 53 Brazilian DFL patients median age 58.2 years (33-85), males comprising 50% (

10.1080/10428194.2024.2401098 article EN cc-by Leukemia & lymphoma/Leukemia and lymphoma 2024-09-10

10.1016/j.htct.2024.09.1980 article PT cc-by-nc-nd Hematology Transfusion and Cell Therapy 2024-10-01

10.1590/0037-8682-0634-2021 article EN cc-by Revista da Sociedade Brasileira de Medicina Tropical 2022-01-01

Introduction: Adult T-cell leukemia/lymphoma (ATL) is a peripheral malignancy caused by human leukemia virus type I (HTLV-1), endemic in some areas of the world, such as Brazil. Between 3% and 5% HTLV-1-infected individuals develop ATL after long latency. The clinical features are heterogeneous classified into acute, lymphoma, chronic smoldering types. Acute lymphoma types defined aggressive whereas others indolent ATL. On April 2017, Brazil project was launched. Methods: Ambispective...

10.1002/hon.3164_361 article EN Hematological Oncology 2023-06-01
Coming Soon ...