A5047596391- Traumatic Brain Injury and Neurovascular Disturbances
- Cerebrospinal fluid and hydrocephalus
- Optical Imaging and Spectroscopy Techniques
- Organ Donation and Transplantation
- Neurosurgical Procedures and Complications
- Cerebral Venous Sinus Thrombosis
- Acute Ischemic Stroke Management
- Hemodynamic Monitoring and Therapy
- Cerebrovascular and Carotid Artery Diseases
- Traumatic Brain Injury Research
- Organ Transplantation Techniques and Outcomes
- S100 Proteins and Annexins
- Long-Term Effects of COVID-19
- Intraoperative Neuromonitoring and Anesthetic Effects
- Renal and Vascular Pathologies
- Epilepsy research and treatment
- Grief, Bereavement, and Mental Health
- Cardiac Arrest and Resuscitation
- Stroke Rehabilitation and Recovery
- Drug-Induced Hepatotoxicity and Protection
- Blood donation and transfusion practices
- Berberine and alkaloids research
- Autopsy Techniques and Outcomes
- Neuroinflammation and Neurodegeneration Mechanisms
- Sepsis Diagnosis and Treatment
Universidade de São Paulo
2019-2025
Tech Foundation
2024
University of Cambridge
2023
University of Genoa
2023
Escola Bahiana de Medicina e Saúde Pública
2023
Weatherford College
2023
Instituto Português de Oncologia de Coimbra Francisco Gentil
2023
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2015-2021
North China Electric Power University
2020
Capital Medical University
2020
Background: We validated a new noninvasive tool (B4C) to assess intracranial pressure waveform (ICPW) morphology in set of neurocritical patients, correlating the data with ICPW obtained from invasive catheter monitoring. Materials and Methods: Patients undergoing (ICP) monitoring were consecutively evaluated using B4C sensor. Ultrasound-guided manual internal jugular vein (IJV) compression was performed elevate ICP baseline. values, amplitudes, time intervals (P2/P1 ratio time-to-peak...
Abstract Analysis of intracranial pressure waveforms (ICPW) provides information on compliance. We aimed to assess the correlation between noninvasive ICPW (NICPW) and invasively measured (ICP) NICPW prognostic value in this population. In cohort, acute brain-injured (ABI) patients were included within 5 days from admission six Intensive Care Units. Mean ICP (mICP) values P2/P1 ratio derived analyzed correlated with outcome, which was defined as: (a) early death (ED); survivors spontaneous...
: One of the possible mechanisms by which new coronavirus (SARS-Cov2) could induce brain damage is impairment cerebrovascular hemodynamics (CVH) and intracranial compliance (ICC) due to elevation pressure (ICP). The main objective this study was assess presence CVH ICC alterations in patients with COVID-19 evaluate their association short-term clinical outcomes.
Abstract Background Numerous trials have addressed intracranial pressure (ICP) management in neurocritical care. However, identifying its harmful thresholds and controlling ICP remain challenging terms of improving outcomes. Evidence suggests that an individualized approach is necessary for establishing tolerance limits ICP, incorporating factors such as waveform (ICPW) or pulse morphology along with additional data provided by other invasive (e.g., brain oximetry) noninvasive monitoring...
Background: Morphological alterations in intracranial pressure (ICP) pulse waveform (ICPW) secondary to hypertension (ICP >20 mmHg) and a reduction compliance (ICC) are well known indicators of neurological severity. The exclusive exploration modifications ICPW after either the loss skull integrity or surgical procedures for resolution is not common approach studied. present study aimed assess morphological among neurocritical care patients with defects decompressive craniectomy (DC) by...
Critical closing pressure (CrCP) and resistance-area product (RAP) have been conceived as compasses to optimize cerebral perfusion (CPP) monitor cerebrovascular resistance, respectively. However, for patients with acute brain injury (ABI), the impact of intracranial (ICP) variability on these variables is poorly understood. The present study evaluates effects a controlled ICP variation CrCP RAP among ABI.Consecutive neurocritical monitoring were included along transcranial Doppler invasive...
Transcranial Doppler (TCD) is a repeatable, at‐the‐bedside, helpful tool for confirming cerebral circulatory arrest (CCA). Despite its variable accuracy, TCD increasingly used during brain death determination, and it considered among the optional ancillary tests in several countries. Among limitations, need skilled operators with appropriate knowledge of typical CCA patterns lack adequate acoustic bone windows intracranial arteries assessment are critical. The purpose this review to describe...
Abstract Neurocritical patients frequently exhibit abnormalities in cerebral hemodynamics (CH) and/or intracranial compliance (ICC), all of which significantly impact their clinical outcomes. Transcranial Doppler (TCD) and the cranial micro-deformation sensor (B4C) are valuable techniques for assessing CH ICC, respectively. However, there is a scarcity data regarding predictive value these determining patient We prospectively included neurocritical undergoing pressure (ICP) monitoring within...
Cerebral perfusion pressure (CPP) is normally expressed by the difference between mean arterial blood (MAP) and intracranial (ICP) but comparison of separate contributions MAP ICP to human cerebral flow autoregulation has not been reported. In patients with acute brain injury (ABI), internal jugular vein compression (IJVC) was performed for 60 s. Dynamic (dCA) assessed in recordings middle artery velocity (MCAv, transcranial Doppler), invasive measurements ICP. Patients were separated...
OBJECTIVE The present study was designed to answer several concerns disclosed by systematic reviews indicating no evidence support the use of computed tomography angiography (CTA) in diagnosis brain death (BD). Therefore, aim this assess effectiveness CTA for BD and define optimal tomographic criteria intracranial circulatory arrest. METHODS A unicenter, prospective, observational case-control undertaken. Comatose patients (Glasgow Coma Scale score ≤ 5), even those presenting with first...
Multiple factors have been identified as causes of intracranial compliance impairment (ICCI) among patients with obesity. On the other hand, obesity has linked worst outcomes in COVID-19. Thus, hypothesis severe acute respiratory syndrome (SARS) conducing to cerebral hemodynamic disorders (CHD) able worsen ICCI and play an additional role on prognosis determination for COVID-19 obese becomes suitable.50 cases SARS by were evaluated, presence cerebrovascular circulatory disturbances...