A5079716431- COVID-19 Clinical Research Studies
- Sepsis Diagnosis and Treatment
- SARS-CoV-2 and COVID-19 Research
- Organ Donation and Transplantation
- Pneumonia and Respiratory Infections
- Antibiotic Resistance in Bacteria
- Traumatic Brain Injury and Neurovascular Disturbances
- Respiratory Support and Mechanisms
- PARP inhibition in cancer therapy
- Bacterial Identification and Susceptibility Testing
- Intensive Care Unit Cognitive Disorders
- Blood donation and transfusion practices
- Organ Transplantation Techniques and Outcomes
- COVID-19 and Mental Health
- Pain Management and Opioid Use
- Antimicrobial Resistance in Staphylococcus
- Transcranial Magnetic Stimulation Studies
- Family and Patient Care in Intensive Care Units
- Palliative Care and End-of-Life Issues
- Anesthesia and Neurotoxicity Research
- Hemodynamic Monitoring and Therapy
- Renal and Vascular Pathologies
- Renal Transplantation Outcomes and Treatments
- Pain Mechanisms and Treatments
- Cardiac, Anesthesia and Surgical Outcomes
University of Rome Tor Vergata
2010-2025
Policlinico Tor Vergata
2007-2023
Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda
2022
Bambino Gesù Children's Hospital
2020
Medicina
2006
Laboratoire Mathématiques, Image et Applications
2006
St. Eugenio Hospital
2002
With the aim to individuate alleles that may reflect a higher susceptibility disease, in present study we analyzed HLA allele frequency distribution group of 99 Italian patients affected by severe or extremely form COVID-19. After application Bonferroni's correction for multiple tests, significant association was found HLA-DRB1*15:01, -DQB1*06:02 and -B*27:07, after comparing results reference 1017 individuals, previously typed our laboratory. The increased frequencies observed contribute...
Coagulase-negative staphylococci (CoNS) are a major cause of nosocomial blood stream infection, especially in critically ill and haematology patients. CoNS usually multidrug-resistant glycopeptide antibiotics have been to date considered the drugs choice for treatment. The aim this study was characterize with reduced susceptibility glycopeptides causing infection (BSI) patients at University Hospital Tor Vergata, Rome, Italy, 2007.Hospital microbiology records transplant ICU were reviewed...
Abstract Background Coronaviruses (CoV) are a large family of viruses that common in humans and many animal species. Animal coronaviruses rarely infect with the exceptions Middle East respiratory syndrome ( MERS-CoV ), severe acute corona virus (SARS-CoV), now SARS-CoV-2, which is cause ongoing pandemic coronavirus disease 2019 (COVID-19). Several studies suggested genetic variants ACE2 gene may influence host susceptibility or resistance to SARS-CoV-2 infection according functional role...
The nosocomial infections surveillance system must be strongly effective especially in highly critic areas, such as Intensive Care Units (ICU). These areas are frequently an epidemiological epicentre for transmission of multi-resistant pathogens, like Acinetobacter baumannii. As epidemic outbreak occurs it is very important to confirm or exclude the genetic relationship among isolates a short time. There several molecular typing systems used with this aim. Repetitive sequence-based PCR...
Transcranial Doppler (TCD) is a repeatable, at‐the‐bedside, helpful tool for confirming cerebral circulatory arrest (CCA). Despite its variable accuracy, TCD increasingly used during brain death determination, and it considered among the optional ancillary tests in several countries. Among limitations, need skilled operators with appropriate knowledge of typical CCA patterns lack adequate acoustic bone windows intracranial arteries assessment are critical. The purpose this review to describe...
The emergence of KPC-producing K. pneumoniae has now become a global concern. KPC beta-lactamases are plasmid-borne and, like extended spectrum beta lactamases (ESBLs), can accumulate and transfer resistance determinants to other classes antibiotics. Therefore, infection control guidelines on early identification the spread organisms carrying these resistant needed. Klebsiella carbapenemase (KPC) was detected in two isolates carbapenem-resistant obtained from patients at an Italian teaching...
Opioids may alleviate chronic neuropathic pain (NP), but are considered second/third-line analgesia due to their poor gastrointestinal (GI) tolerability. A fixed combination of prolonged-release oxycodone and naloxone (OXN) has been developed overcome the GI effects. The aim this analysis was evaluate analgesic effectiveness tolerability low-dose OXN in patients with moderate-to-severe noncancer NP despite analgesia.This retrospective observation consecutive adult patients, treated...
Bacterial meningitis and septicemia are invasive bacterial diseases, representing a significant cause of morbidity mortality worldwide. Both conditions characterized by an impressive inflammatory response, resulting rapidly in cerebral edema, infarction, hydrocephalus, septic shock with multiple organ failure. Despite advances critical care, outcome prognosis remain critical. Available adjunctive treatments to control the response have shown encouraging results evolution patients sepsis...
Background In this study, the Keynesian principle “savings may be used as investments in resources” is applied to Kidney Transplantation (KT), contextualizing whole Organs Donation and (ODT) service a unique healthcare entity. Our aim was define financial resources that acquired form of savings from KT activity. Methods We analyzed registry funding data for ODT our region, between 2015 2019. hypotheses aimed evaluate whether would offset Organ (OD) costs, scope growth, estimate what could...
Coronavirus disease 2019 (COVID-19) presents a clinical spectrum that ranges from mild condition to critical illness. Patients with illness present respiratory failure, septic shock and/or multi-organ failure induced by the so called "cytokine storm". Inflammatory cytokines affect iron metabolism, mainly inducing synthesis of hepcidin, hormone peptide not routinely measured. High levels hepcidin have been associated severity COVID-19. The aim this study was analyze, retrospectively, in group...
The presentation of carbon monoxide poisoning is non-specific and highly variable. Hyperbaric oxygen therapy used for the treatment this condition. Various reports show occurrence self-limiting seizures after as a consequence hyperbaric therapy. Contrary to seizures, status epilepticus has been rarely observed in these conditions. exact pathophysiology underlying associated with not really clear, some elements appear be common both We describe case non-convulsive patient treated mechanism,...
In the past two pandemic years, Emergency Departments (ED) have been overrun with COVID-19-suspicious patients. Some data on role played by laboratory biomarkers in early risk stratification of COVID-19 patients recently published. The aim this study is to assess potential new biomarker mid-regional proadrenomedullin (MR-proADM) stratifying in-hospital mortality at triage. A further goal present evaluate whether MR-proADM together other biochemical markers could play a key assessing correct...