Monica Rocco
- Respiratory Support and Mechanisms
- Intensive Care Unit Cognitive Disorders
- Nosocomial Infections in ICU
- Sepsis Diagnosis and Treatment
- Hemodynamic Monitoring and Therapy
- COVID-19 Clinical Research Studies
- Cardiac Arrest and Resuscitation
- Cardiovascular and Diving-Related Complications
- Anesthesia and Pain Management
- Traumatic Brain Injury and Neurovascular Disturbances
- Airway Management and Intubation Techniques
- Acute Kidney Injury Research
- Diabetic Foot Ulcer Assessment and Management
- Antibiotic Use and Resistance
- Long-Term Effects of COVID-19
- COVID-19 and healthcare impacts
- Antibiotic Resistance in Bacteria
- Family and Patient Care in Intensive Care Units
- Cardiac, Anesthesia and Surgical Outcomes
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Anesthesia and Sedative Agents
- Pharmacological Effects and Toxicity Studies
- Ultrasound in Clinical Applications
- Pleural and Pulmonary Diseases
- Central Venous Catheters and Hemodialysis
Sapienza University of Rome
2016-2025
Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro
2024
Universidade Federal do Rio de Janeiro
2024
University of Salerno
2022
Azienda Ospedaliera Sant'Andrea
2015-2021
IRCCS Policlinico San Donato
2020-2021
RELX Group (United States)
2021
Policlinico Umberto I
1998-2018
Universitat Autònoma de Barcelona
2017-2018
University of Molise
2018
The role of noninvasive positive-pressure ventilation delivered through a face mask in patients with acute respiratory failure is uncertain. We conducted prospective, randomized trial as compared endotracheal intubation conventional mechanical 64 hypoxemic who required ventilation.
Noninvasive ventilation (NIV) has been associated with lower rates of endotracheal intubation in populations patients acute respiratory failure.To compare NIV standard treatment using supplemental oxygen administration to avoid recipients solid organ transplantation hypoxemic failure.Prospective randomized study conducted at a 14-bed, general intensive care unit university hospital.Of 238 who underwent from December 1995 October 1997, 51 were treated for failure. Of these, 40 eligible and 20...
BACKGROUND Ischemic cardiomyopathy is characterized by myocyte loss, reactive cellular hypertrophy, and ventricular scarring. However, the relative contribution of these tissue processes to late failure remains be determined. METHODS AND RESULTS Ten hearts were obtained from individuals undergoing cardiac transplantation as a result chronic coronary artery disease in its terminal stage. An identical number control collected at autopsy patients who died causes other than cardiovascular...
In randomized studies of heterogeneous patients with hypoxemic acute respiratory failure, noninvasive positive pressure ventilation (NPPV) was associated a significant reduction in endotracheal intubation. The role NPPV distress syndrome (ARDS) is still unclear. objective to investigate the application as first-line intervention early ARDS, describing what happens everyday clinical practice centers having expertise NPPV.Prospective, multiple-center cohort study.Three European intensive care...
To examine whether a significant circadian variation of transient myocardial ischemia exists and to better understand the character such variation, 32 patients with chronic stable symptoms coronary artery disease underwent one or more days ambulatory monitoring ischemic ST segment changes during daily life. A total 251 episodes depression occurred in 24 (75%) median duration 5 min (range 1 253). increase activity was found 39% 46% time occurring between 6 A.M. 12 P.M. (p less than .05 p =...
Several factors have been proposed to explain the high death rate of coronavirus disease 2019 (COVID-19) outbreak, including hypertension and hypertension-related treatment with Renin Angiotensin System inhibitors. Also, age multimorbidity might be confounders. No sufficient data are available demonstrate their independent role. We designed a cross-sectional, observational, multicenter, nationwide survey in Italy verify whether renin-angiotensin system inhibitors related COVID-19 severe...
The mechanism responsible for the attenuated heart rate (HR) response to exercise in patients with congestive failure (CHF) was investigated 46 normal subjects and 59 CHF stratified by peak oxygen consumption (VO2). HR increment from rest were decreased patients, both correlated strongly VO2 (r = 0.810, p less than 0.0001; r 0.863, 0.0001, respectively). Peak norepinephrine level (NE) NE not patients. Resting elevated inversely -0.595, 0.001). However, no significant correlation occurred...
Abstract Introduction In ICUs, both fluid overload and oliguria are common complications associated with increased mortality among critically ill patients, particularly in acute kidney injury (AKI). Although is an expected complication of oliguria, it remains unclear whether their effects on independent each other. The aim this study to evaluate the impact balance urine volume outcomes determine they behave as predictors adult ICU patients AKI. Methods We performed a secondary analysis data...
Background. Mitochondrial DNA (MT-DNA) are intrinsically inflammatory nucleic acids released by damaged solid organs. Whether circulating cell-free MT-DNA quantitation could be used to predict the risk of poor COVID-19 outcomes remains undetermined.
To assess the relations of electrocardiographic measures ischemia with development adverse coronary events, 86 patients stable artery disease and positive exercise tests for myocardial underwent ambulatory monitoring electrocardiogram. Monitoring was performed after withdrawal antianginal medications, prospective follow-up obtained on routine medical care as prescribed by physicians who were unaware monitor results. Forty-nine (57%) had a total 426 episodes ST segment depression; only 60...
Because of scarce data from larger series and nonhomogeneous selection criteria, further information is needed on peritonectomy with hyperthermic intraperitoneal chemotherapy (HIPEC) in managing patients ovarian peritoneal carcinomatosis.In an open, prospective, single-center nonrandomized phase 2 study conducted November 2000 to April 2007, 47 primary advanced or recurrent cancer diffuse carcinomatosis were enrolled; 22 underwent 25 secondary cytoreduction plus immediate HIPEC followed by...
Noninvasive positive pressure ventilation (NPPV) with a facemask (FM) is effective in patients acute exacerbation of their chronic obstructive pulmonary disease. Whether it feasible to treat these NPPV delivered by helmet not known.Over 4-month period, the authors studied 33 disease who were admitted four intensive care units and treated NPPV. The compared historical controls FM NPPV, matched for simplified physiologic score (SAPS II), age, PaCO2, pH, PaO2:fractional inspired oxygen tension....
Abstract Background Cardiometabolic disorders may worsen Covid-19 outcomes. We investigated features and outcomes for patients with or without diabetes, cardiometabolic multimorbidity. Methods collected compared data retrospectively from hospitalized multimorbidity (defined as ≥ two of three risk factors hypertension dyslipidaemia). Multivariate logistic regression was used to assess the primary composite outcome (any mechanical ventilation, admission an intensive care unit [ICU] death) in...
SUMMARY Mitochondrial DNA (MT-DNA) are intrinsically inflammatory nucleic acids released by damaged solid organs. Whether the appearance of cell-free MT-DNA is linked to poor COVID-19 outcomes remains undetermined. Here, we quantified circulating in prospectively collected, plasma samples from 97 subjects with at time hospital presentation. Circulating were sharply elevated patients who eventually died, required ICU admission or intubation. Multivariate regression analysis revealed that high...
Abstract Background The study aimed to describe the epidemiology and outcomes of hospital-acquired bloodstream infections (HABSIs) between COVID-19 non-COVID-19 critically ill patients. Methods We used data from Eurobact II study, a prospective observational multicontinental cohort on HABSI treated in ICU. For current analysis, we selected centers that included both performed descriptive statistics terms patients’ characteristics, source infection microorganism distribution. studied...
The use of arterial partial pressure carbon dioxide (PaCO2) as a target intervention to manage elevated intracranial (ICP) and its effect on clinical outcomes remain unclear. We aimed describe targets for PaCO2 in acute brain injured (ABI) patients assess the occurrence abnormal values during first week intensive care unit (ICU). secondary aim was association with in-hospital mortality. carried out analysis multicenter prospective observational study involving adult invasively ventilated...
Many factors have contributed to rendering frailty an emerging, relevant, and very popular concept. First, many pandemics that affected humanity in history, including COVID-19, most recently, had more severe effects on frail people compared non-frail ones. Second, the increase human life expectancy observed developed countries, Italy has led a rise percentage of older population is likely be frail, which why much common concern among geriatricians other various health-care professionals....