A5056839715- Respiratory Support and Mechanisms
- Hemodynamic Monitoring and Therapy
- Optical Imaging and Spectroscopy Techniques
- Non-Invasive Vital Sign Monitoring
- Anesthesia and Pain Management
- Cardiovascular and exercise physiology
- Sepsis Diagnosis and Treatment
- Cardiac, Anesthesia and Surgical Outcomes
- Intensive Care Unit Cognitive Disorders
- Infrared Thermography in Medicine
- Airway Management and Intubation Techniques
- Nosocomial Infections in ICU
- Nausea and vomiting management
- Neonatal Respiratory Health Research
- Diabetic Foot Ulcer Assessment and Management
- Brain Tumor Detection and Classification
- Anesthesia and Sedative Agents
- Peripheral Artery Disease Management
- Photoacoustic and Ultrasonic Imaging
- Cardiovascular and Diving-Related Complications
- Thermoregulation and physiological responses
- Neurological and metabolic disorders
- Antimicrobial Resistance in Staphylococcus
- Mitochondrial Function and Pathology
- Medical Image Segmentation Techniques
Sapienza University of Rome
2015-2024
Azienda Ospedaliera Sant'Andrea
2006-2021
Essa Pharma (United States)
2020
Unione Italiana del Lavoro
2020
Policlinico Umberto I
1991-2015
University of Bari Aldo Moro
1990-2004
Institute of Intelligent Systems for Automation
2003
University of Tennessee Health Science Center
1999
Azienda Universitaria Ospedaliera Consorziale - Policlinico Bari
1997
Erasmus Hospital
1995
The role of noninvasive positive-pressure ventilation delivered through a face mask in patients with acute respiratory failure is uncertain. We conducted prospective, randomized trial as compared endotracheal intubation conventional mechanical 64 hypoxemic who required ventilation.
Several factors have been proposed to explain the high death rate of coronavirus disease 2019 (COVID-19) outbreak, including hypertension and hypertension-related treatment with Renin Angiotensin System inhibitors. Also, age multimorbidity might be confounders. No sufficient data are available demonstrate their independent role. We designed a cross-sectional, observational, multicenter, nationwide survey in Italy verify whether renin-angiotensin system inhibitors related COVID-19 severe...
We applied near-infrared spectroscopy (NIRS) for the simultaneous measurement of forearm blood flow (FBF) and oxygen consumption (VO2) in human by inducing a 50-mmHg venous occlusion. Eleven healthy subjects were studied both at rest after hand exercise during vascular FBF was also measured strain-gauge plethysmography. NIRS 1.9 +/- 0.8 ml.100 ml-1.min-1 8.2 2.9 exercise. These values showed correlation (r = 0.94) with those obtained VO2 4.6 1.3 microM O2 x 100 24.9 11.2 The scatter good...
Background: New ways of decreasing post‐operative analgesic drug requirements are special interest after major surgery. Magnesium sulfate (MgSO 4 ) alters pain processing and reduces the induction maintenance central sensitization by blocking N ‐methyl‐ d ‐aspartate (NMDA) receptor in spinal cord. We investigated whether supplementation anesthesia with combined intrathecally epidurally infused MgSO reduced patients’ analgesia requirements. Methods: In a randomized, prospective, double‐blind,...
Postoperative shivering may be prevented by maintaining normothermia intraoperatively or it treated using specific drugs. The aim of this study was to compare the efficacy nefopam hydrochloride (nefopam) that clonidine and meperidine in patients undergoing elective neurosurgical procedures. Three groups were included study. Patients group A (60) received i.v., at random, 20 mg nefopam, 50 150 μg immediate postoperative period. incidence time which ceased noted, along with central temperature...
The aim of this study was to evaluate the effects propofol administration (2 mg · kg ‐1 i.v.) on airways resistances and respiratory mechanics patients affected by COPD exacerbation, requiring mechanical ventilation. Twenty required anaesthesia for diagnostic or therapeutic procedures. Fourteen consecutive were divided at random into two groups: Group P received C (control) only Intralipid 10%; an additional group six i.v. flunitrazepam (0.03 ). Lung (dynamic static compliance, peak...
Quantitation of neutrophil CD64 expression and procalcitonin (PCT) levels in blood samples have been recently proposed as useful tools for early detection sepsis. To determine the usefulness these tests, we analyzed 112 patients, admitted to an intensive care unit (ICU), presenting clinical symptoms sepsis, well 50 healthy controls. At end study, a retrospective analysis showed that only 52 ICU-patients presented real sepsis (positive culture). The results obtained indicated patients with 49...
ANTONELLI, MASSIMO; CONTI, GIORGIO; ROCCO, MONICA; BUFI, MAURIZIO; DE BLASI, ROBERTO ALBERTO; VIVINO, GABRIELLA; GASPARETTO, ALESSANDRO; MEDURI, GIANFRANCO UMBERTO Author Information
Objective The aim of this study was to examine variables for early prediction successful weaning in chronic obstructive pulmonary disease (COPD) patients during pressure support ventilation weaning. Design Thirteen COPD were pro-spectively studied compare the respiratory pattern (inspiratory time, expiratory total breath cycle duration, tidal volume, rate, minute ventilation), drive (airway occlusion at 0.1 sec, vol-ume/inspiratory time), and blood gases after 30 mins Setting performed...
Although anaesthetics are known to alter microcirculation no study has, our knowledge, documented changes in human skeletal microcirculatory function during general anaesthesia.Forty-four patients undergoing maxillofacial surgery at a university hospital were prospectively randomized receive anaesthesia with remifentanil combined propofol or sevoflurane. Muscle was investigated near-infrared spectroscopy (NIRS) before induced and 30 min later. An NIRS device (NIMO, Nirox) used quantify calf...
Postoperative secondary hyperalgesia arises from central sensitization due to pain pathways facilitation and/or acute opioid exposure. The latter is also known as opioid-induced (OIH). Remifentanil, a potent μ-opioid agonist, reportedly induces postoperative and increases scores consumption. pathophysiology underlying involves N-methyl-D-aspartate (NMDA)-mediated pathways. In this study, we investigated whether perioperatively infusing low-dose buprenorphine, an with anti-NMDA activity, in...