- Blood Pressure and Hypertension Studies
- Heart Rate Variability and Autonomic Control
- Medication Adherence and Compliance
- Renal and Vascular Pathologies
- Pharmaceutical Practices and Patient Outcomes
- Abdominal vascular conditions and treatments
- Analytical Methods in Pharmaceuticals
- Sodium Intake and Health
- Chemotherapy-induced cardiotoxicity and mitigation
- Hemodynamic Monitoring and Therapy
- Cardiovascular Health and Risk Factors
- COVID-19 Clinical Research Studies
- Hormonal and reproductive studies
- Obesity, Physical Activity, Diet
- Cardiovascular Health and Disease Prevention
- Aortic Thrombus and Embolism
- Health and Lifestyle Studies
- Cerebrovascular and Carotid Artery Diseases
- Cardiovascular Issues in Pregnancy
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiovascular and exercise physiology
- Long-Term Effects of COVID-19
- Renal Diseases and Glomerulopathies
- Heart rate and cardiovascular health
- Multicomponent Synthesis of Heterocycles
University of Turin
2019-2025
Ospedale San Giovanni Bosco
2025
Candiolo Cancer Institute
2025
Azienda Ospedaliera Citta' della Salute e della Scienza di Torino
2022-2024
Cliniques Universitaires Saint-Luc
2022-2023
UCLouvain
2022-2023
Several factors have been proposed to explain the high death rate of coronavirus disease 2019 (COVID-19) outbreak, including hypertension and hypertension-related treatment with Renin Angiotensin System inhibitors. Also, age multimorbidity might be confounders. No sufficient data are available demonstrate their independent role. We designed a cross-sectional, observational, multicenter, nationwide survey in Italy verify whether renin-angiotensin system inhibitors related COVID-19 severe...
Objectives: Arterial hypertension is still the most frequent cause of cardiovascular and cerebrovascular morbidity mortality. Antihypertensive treatment has proved effective in reduction risk. Nevertheless, lifestyle interventions pharmacological therapy some cases are ineffective reaching blood pressure target values, despite full dose poly-pharmacological treatment. Poor adherence to medications an important failure. Different methods assess therapeutic currently available: Therapeutic...
Obesity is a significant health problem, with increasing involvement of young population worldwide. The aim this study was to evaluate the effects 2 different types physical exercise (resistance vs. combined aerobic-resistance) on cardiovascular and anthropometric profile sample sedentary adolescents overweight obesity. After undergoing clinical, anthropometric-metabolic evaluation (T0), subjects obesity were randomized 6-month resistance or aerobic-resistance training program. Clinical,...
Background: Management of resistant hypertension (RHTN) is challenging and often implies the use complex polypharmacy interventional therapies. The main objectives this study were (i) to describe characteristics patients with RHTN referred two expert centres; (ii) identify predictors blood pressure (BP) control after intensive management. Methods: We reviewed electronic medical files all for Brussels Torino centres, extracted detailed clinical data, informations on drug adherence...
Abstract The aim of the study was to assess drug adherence, as well association psychological factors with both adherence and severity hypertension in two subtypes patients apparently treatment‐resistant (ATRH): younger uncomplicated (YURHTN) versus ≥60‐year‐old and/or a history cardio‐ or cerebrovascular complication (OCRHTN). Drug assessed urine by targeted Liquid Chromatography‐Mass Spectrometry. 24‐h ambulatory blood pressure adjusted for number antihypertensive drugs adherence....
Objective: Blood pressure variability (BPV) is an independent predictor of cardiovascular (CV) events and overall mortality. The potential role BPV in defining CV risk patients undergoing anticancer therapy with a cancer therapy-related toxicity (CTR-CVT) currently unknown. aims this study were: (i) to assess the predictive value indexes for CTR-CVT development corresponding cut-off values; (ii) identify subgroups subjects based on BPV, through clustering analysis. Design method: Patients...
Abstract Objective: 2016 European Society Hypertension (ESH) and 2017 American Academy of Paediatrics (AAP) guidelines on hypertension in children adolescents substantially diverge, for the first time, definition hypertension. The aim this study was to retrospectively assess impact two different prevalence high blood pressure a population obese normal-weight adolescents. Design method: This included an historical cohort 624 subjects age range 2–18 years, among referred Paediatric...
A 35-year-old woman, with a known history of right renal artery FMD, presented at the Hypertension Outpatient Clinic for evaluation resistant hypertension. The patient was an active smoker and had single kidney after left nephrectomy malformation during childhood. diagnosis FMD been made on occasion previous pregnancy 23 years, complicated by preeclampsia angioplasty performed. Work-up disclosed recurrence stenosis, new Blood pressure normalized procedure. At 36 another pregnancy, also...
The International Consensus on Fibromuscular Dysplasia (FMD) (Gornik, Persu et al. J Hypertens. 2019;37:229–252; Vasc Med. 2019;24:164–189) provided a comprehensive summary of the clinical history, diagnosis and management FMD. However, authors admitted that most current knowledge FMD has been acquired in patients Caucasian descent. Accordingly, they expressed their commitment to include higher proportion non-white ethnicities existing registries. Along these lines, European Registry...
Objective: Renal denervation (DRN) is one of the invasive therapeutic approaches resistant arterial hypertension. The aim this study was to re-evaluate patients undergoing DRN, in terms safety and efficacy. Design method: A retrospective evaluation DRN between 01/01/2011 31/12/2021 Arterial Hypertension Center Turin. Results: series included 14 subjects, which 8 (57%) were female with an average age 54±10 years. number antihypertensive drugs before renal 5.7±1.0 at baseline blood pressure...
Objective: It has been demonstrated that obesity in childhood and adolescence may lead to cardiovascular alterations early onset of organ damage. Our aim was assess the effects 6 months aerobic or anaerobic physical activity on profile young obese patients with without arterial hypertension. Design method: In period between June December 2017, we enrolled 20 consecutive subjects moderate severe referred our Hypertension Unit. We performed a evaluation heart rate variability (HRV) by...
Altered psychological profiles are associated with drug adherence and resistance in patients resistant hypertension (RHTN). However, treatment may also result from increased arterial stiffness target organ damage. The aim of this study was to assess the association factors both two subtypes RHTN: younger without cardiovascular complications versus older or vascular patients.Ninety-seven RHTN were enrolled split groups: 60y previous diseases (VRHTN), (NVRHTN). Drug assessed by urinary Liquid...
Introduction: Blood pressure (BP) regulation is affected by ageing through different mechanisms, including alteration of neural control. variability (BPV) and heart rate (HRV) reflect the interaction BP control both increased BPV reduced HRV have been associated to cardiovascular morbidity mortality. The objective this study was assess in hypertensive subjects age ranges compare them with established primary dysautonomia, i.e., Parkinson related diseases. Methods: will include 1,439...
Fibromuscular dysplasia (FMD) is a non-atherosclerotic, non-inflammatory arterial disease of unclear origin, that may affect virtually all middle-sized arteries, mostly found in young or middle-aged women. More than half patients have lesions two more beds. While many cases are asymptomatic associated with aspecific symptoms (mild hypertension, migraines, tinnitus), number develop severe complications such as resistant carotid dissection, early stroke mesenteric ischemia. Two subtypes FMD...
Objective: Hypertension is a cardiovascular and cerebrovascular risk factor. Prevention of hypertension mediated organ damage main health problem. Guidelines underlines the importance screening educational programs in general population role non-medical sanitary subjects, particularly pharmacists. This study evaluated knowledge about afferent to community pharmacies Piedmont Ligury. Design method: A questionnaire has been collected from 2731 pharmacy costumers, participating an arterial...