Ivana Rabbone
- Diabetes Management and Research
- Diabetes and associated disorders
- Pancreatic function and diabetes
- Diabetes Treatment and Management
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- COVID-19 Clinical Research Studies
- Diet and metabolism studies
- Obesity, Physical Activity, Diet
- Lipoproteins and Cardiovascular Health
- Celiac Disease Research and Management
- Metabolism, Diabetes, and Cancer
- COVID-19 and healthcare impacts
- Mobile Health and mHealth Applications
- Cardiovascular Function and Risk Factors
- Heart Rate Variability and Autonomic Control
- COVID-19 Impact on Reproduction
- Growth Hormone and Insulin-like Growth Factors
- Childhood Cancer Survivors' Quality of Life
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Adolescent and Pediatric Healthcare
- Diet, Metabolism, and Disease
- Respiratory viral infections research
- Adipose Tissue and Metabolism
- Microbial Metabolites in Food Biotechnology
- COVID-19 and Mental Health
Università degli Studi del Piemonte Orientale “Amedeo Avogadro”
2020-2025
Azienda Ospedaliero Universitaria Maggiore della Carita
2020-2025
The University of Adelaide
2024
University of Bari Aldo Moro
2024
Hospital General Universitario de Elche
2024
Semnan University of Medical Sciences
2024
Cornell University
2024
University of Virginia
2024
Rutgers, The State University of New Jersey
2024
Azienda Unità Sanitaria Locale Della Romagna
2024
We conducted a retrospective survey in pediatric centers belonging to the Italian Society for Pediatric Diabetology and Endocrinology. The following data were collected all new-onset diabetes patients aged 0–18 years: DKA (pH < 7.30), severe 7.1), preschool children, treatment according ISPAD protocol, type of rehydrating solution used, bicarbonates use, amount insulin infused. Records<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="M1"><mml:mo...
Data on features of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in children and adolescents are scarce. We report preliminary results an Italian multicentre study comprising 168 laboratory-confirmed paediatric cases (median: 2.3 years, range: 1 day-17.7 55.9% males), which 67.9% were hospitalised 19.6% had comorbidities. Fever was the most common symptom, gastrointestinal manifestations frequent; two required intensive care, five seizures, 49 received experimental treatments...
OBJECTIVE To evaluate whether the diagnosis of pediatric type 1 diabetes or its acute complications changed during early phase coronavirus disease 2019 (COVID-19) pandemic in Italy. RESEARCH DESIGN AND METHODS This was a cross-sectional, web-based survey all Italian centers to collect diabetes, diabetic ketoacidosis (DKA), and COVID-19 data patients presenting with new-onset established between 20 February 14 April 2020. RESULTS Fifty-three 68 (77.9%) responded. There 23% reduction new cases...
Abstract Objective : To investigate the cardiovascular autonomic function in pediatric obesity of different duration by using standard time domain, spectral heart rate variability (HRV), and nonlinear methods. Research Methods Procedures Fifty obese children (13.9 ± 1.7 years) were compared with 12 lean subjects (12.9 1.6 years). Obese classified as recent (ROB) (<4 years), intermediate (IOB) (4 to 7 long‐term (OB) (>7 In all participants, we performed blood pressure (BP) measurements,...
To better understand the role of lecithin:cholesterol acyltransferase (LCAT) in lipoprotein metabolism through genetic and biochemical characterization families carrying mutations LCAT gene.Thirteen 17 different gene were identified by Lipid Clinics Departments Nephrology throughout Italy. DNA analysis 82 family members 15 carriers 2 mutant alleles, 11 with familial deficiency (FLD) 4 fish-eye disease (FED). Forty-four individuals carried 1 allele, 23 had a normal genotype. Plasma...
An etiologic diagnosis of diabetes can affect the therapeutic strategy and prognosis chronic complications. The aim present study was to establish relative percentage different subtypes in patients attending Italian pediatric centers influence an on therapy. This a retrospective study. clinical records 3781 consecutive (age, 0 18 years) referred 15 clinics with or impaired fasting glucose from January 1, 2007 December 31, 2012 were examined. characteristics at their first referral centers,...
OBJECTIVE The Pediatric Artificial Pancreas (PedArPan) project tested a children-specific version of the modular model predictive control (MMPC) algorithm in 5- to 9-year-old children during camp. RESEARCH DESIGN AND METHODS A total 30 children, 9-years old, with type 1 diabetes completed an outpatient, open-label, randomized, crossover trial. Three days artificial pancreas (AP) were compared three parent-managed sensor-augmented pump (SAP). RESULTS Overnight time-in-hypoglycemia was reduced...
On 20 February 2020, so-called Italian Patient 1 was admitted to the intensive care unit of his local hospital due a deteriorating clinical condition from SARS-CoV-2/COVID-19 infection. In Italy, COVID-19 originated handful small towns in northern Italy that were swiftly placed into lockdown. Lockdown Milan, Venice, Rimini and their provinces neighbouring cities followed on 8 March whole 9 March, when ‘#stayhome’ (#iostoacasa) executive order issued. This remained place until after Easter,...
Abstract Background In response to the COVID-19 pandemic, drastic measures for social distancing have been introduced also in Italy, likely with a substantial impact delicate conditions like pregnancy and puerperium. The study aimed investigate changes lifestyle, access health services, mental wellbeing during first Italian lockdown sample of pregnant women new mothers. Methods We carried out web-based survey evaluate how mothers were coping lockdown. collected data about healthy habits...
The restrictive measures adopted worldwide against SARS-CoV-2 produced a drastic reduction in respiratory pathogens, including RSV, but dramatic rebound was thereafter reported. In this multicenter retrospective observational study 15 Pediatric Emergency Departments, all children <3 years old with RSV infection admitted between 1 September and 31 December 2021 were included compared to those the same period of 2020 2019. primary aim evaluate epidemiology during after COVID-19 pandemic...
OBJECTIVE To investigate glucose metrics and identify potential predictors of the achievement glycemic outcomes in children adolescents during their first 12 months MiniMed 780G use. RESEARCH DESIGN AND METHODS This multicenter, longitudinal, real-world study recruited 368 with type 1 diabetes (T1D) starting SmartGuard technology between June 2020 2022. Ambulatory profile data were collected a 15-day run-in period (baseline), 2 weeks after automatic mode activation, every 3 months. The...
Abstract —Seventy-one mutations of the low density lipoprotein (LDL) receptor gene were identified in 282 unrelated Italian familial hypercholesterolemia (FH) heterozygotes. By extending genotype analysis to families index cases, we 12 mutation clusters and localized them specific areas Italy. To evaluate impact these on clinical expression FH, separated into 2 groups: receptor-defective receptor-negative, according LDL defect caused by each mutation. These groups comparable terms patients’...
To evaluate physicians' adjustments of insulin pump settings based on continuous glucose monitoring (CGM) for patients with type 1 diabetes and to compare these automated dose adjustments.A total 26 physicians from 16 centres in Europe, Israel South America participated the study. All were asked adjust dosing pump, CGM glucometer downloads 15 (mean age 16.2 ± 4.3 years, six female, mean glycated haemoglobin 8.3 0.9% [66.8 7.3 mmol/mol]) gathered over a 3-week period. Recommendations compared...
Until recently, in Italy, the use of continuous glucose monitoring (CGM) systems has been limited, but is now rapidly increasing, including so-called real-time CGM (rtCGM) and intermittently viewed (iCGM), also called Flash Glucose Monitoring (FGM). These technologies overcome many limitations self-monitoring blood (SMBG) by fingerprick allow to go beyond HbA1c check control diabetes. However, standardized protocols for applying interpreting rtCGM FGM data are lacking. In this paper, we...
Background: Glucose sensors consist of real-time continuous glucose monitoring (rtCGM) and intermittently scanned CGM (isCGM). Their clinical use has been widely increasing during the past 5 years. The aim this study is to evaluate percentage time in range (TIR) a large group children with type 1 diabetes (T1D) using nonautomated insulin delivery systems, real-world setting. Methods: An 11-center cross-sectional was conducted January-May 2019. Children T1D <18 years, all rtCGM or isCGM for...
<h3>Importance</h3> Severe gastrointestinal (GI) manifestations have been sporadically reported in children with COVID-19; however, their frequency and clinical outcome are unknown. <h3>Objective</h3> To describe the clinical, radiological, histopathologic characteristics of COVID-19 presenting severe GI to identify factors associated a outcome. <h3>Design, Setting, Participants</h3> A multicenter retrospective cohort study (February 25, 2020, January 20, 2021) enrolled inpatient outpatient...
Our aim was to evaluate adherence the Mediterranean diet (MedDiet) among children and adolescents with type 1 diabetes (T1D) in relation metabolic control. Adherence MedDiet assessed Diet Quality Index (KIDMED) questionnaire physical activity by International Physical Activity Questionnaire for Adolescent (IPAQ-A) on 65 subjects (32 males, 9-18 years) T1D. Clinical evaluation performed (standardized body mass index (BMI-SDS), hemoglobin A1C (HbA1c), continuous glucose monitoring metrics when...
In the last decade Sanger method of DNA sequencing has been replaced by next-generation (NGS). NGS is valuable in conditions characterized high genetic heterogeneity such as neonatal diabetes mellitus (NDM).
Objective: To document current practices using continuous subcutaneous insulin infusion (CSII) by downloading electronically the 90-d pump data held within memory and relating that to clinical from children adolescents in different pediatric diabetes centers Europe Israel. Methods: Data of patients (1–18 yr) treated with CSII 23 nine European countries Israel were recorded encapture software (PEC International, Frankfurt, Germany). The number who participated was 377 (48% female; mean...
Objective To identify the role of family's socio-economic and clinical characteristics on metabolic control in children adolescents with type 1 diabetes. Methods In this cross-sectional, multicentre study, 768 subjects diabetes under 18 years age were consecutively recruited from January 2008 to February 2009. Target condition was considered for HbA1c values <7.5% (<58 mmol/mol). A multiple correspondence analysis (MCA) performed analyze association between participants. logistic regression...