A5002314055- Diabetes Management and Research
- Diabetes and associated disorders
- Pancreatic function and diabetes
- Microbial Metabolites in Food Biotechnology
- Celiac Disease Research and Management
- Cystic Fibrosis Research Advances
- Digestive system and related health
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Cardiovascular Function and Risk Factors
- Child Nutrition and Feeding Issues
- Diet, Metabolism, and Disease
- Gout, Hyperuricemia, Uric Acid
- Endoplasmic Reticulum Stress and Disease
- Diet and metabolism studies
- Medication Adherence and Compliance
- Bartonella species infections research
- Neurological and metabolic disorders
- Patient-Provider Communication in Healthcare
- Syphilis Diagnosis and Treatment
- Adolescent and Pediatric Healthcare
- Respiratory viral infections research
- Renal Diseases and Glomerulopathies
- Family and Patient Care in Intensive Care Units
- Galectins and Cancer Biology
- Vitamin D Research Studies
Santobono Children's Hospital
2025
University of Naples Federico II
2014-2023
Ospedali Riuniti San Giovanni di Dio e Ruggi d'Aragona
2023
Federico II University Hospital
2021-2022
Virtual High School
2022
OBJECTIVE To investigate glucose metrics and identify potential predictors of the achievement glycemic outcomes in children adolescents during their first 12 months MiniMed 780G use. RESEARCH DESIGN AND METHODS This multicenter, longitudinal, real-world study recruited 368 with type 1 diabetes (T1D) starting SmartGuard technology between June 2020 2022. Ambulatory profile data were collected a 15-day run-in period (baseline), 2 weeks after automatic mode activation, every 3 months. The...
Aim/Hypothesis To compare the frequency of diabetic ketoacidosis (DKA) at diagnosis type 1 diabetes in Italy during COVID-19 pandemic 2020 with DKA 2017-2019. Methods Forty-seven pediatric centers caring for >90% young people recruited 4,237 newly diagnosed children between 2017 and a longitudinal study. Four subperiods were defined based on government-imposed containment measures COVID-19, frequencies severe compared same periods Results Overall, increased from 35.7% (95%CI,...
We report on a 3-year and 5-month-old boy who was referred for suspected rickets, due to knee valgus deformity developed over the previous year. The child had history of epilepsy well-controlled with phenobarbital. His psychomotor development growth metrics were appropriate his age. On admission, laboratory work-up revealed elevated alkaline phosphatase (1289 U/L) parathyroid hormone (PTH) (417 pg/ml), normal corrected calcium (9,3 mg/dl) creatinine (0,21 mg/dl), low phosphate (3,2...
To evaluate the impact of a virtual educational camp (vEC) on glucose control in children and adolescents with type 1 diabetes using closed-loop (CLC) system.This was prospective multicentre study Tandem Basal-IQ system. Insulin pumps were upgraded to Control-IQ, their parents participated 3-day multidisciplinary vEC. Clinical data, metrics HbA1c evaluated over 12 weeks prior Control-IQ update after vEC.Forty-three (aged 7-16 years) families The median percentage time target range (70-180...
To date, no consistent data are available on the possible impact of CFTR modulators glucose metabolism. The aim this study was to test hypothesis that treatment with is associated an improvement in key direct determinants regulation children and young adults affected by Cystic Fibrosis (CF).In study, 21 CF patients aged 10-25 underwent oral tolerance (OGTT) before after 12-18 months Lumacaftor/Ivacaftor or Elexacaftor-Ivacaftor-Tezacaftor. β-cell function (i.e., first second phase insulin...
Abstract Background Given that the widely acknowledged influence of doctor-patient relationship on objective health parameters and treatment adherence in chronic illnesses, this study sought to explore how patients perceived patient-doctor across virtual in-person contexts. Methods Parents’ patients’ perceptions were evaluated 610 children adolescents (12.17 ± 4.19 years, 50.9% girls) with type 1 diabetes who visited via video-conferencing or person during COVID-19 pandemic. Results No...
Individuals with thiamine-responsive megaloblastic anemia (TRMA) mainly manifest macrocytic anemia, sensorineural deafness, ocular complications, and nonautoimmune diabetes. Macrocytic diabetes may be responsive to high-dosage thiamine treatment, in contrast deafness. Little is known about the efficacy of treatment on manifestations.Our objective report data from four Italian TRMA patients: Cases 1, 2 3, diagnosis was made at 9, 14 27 months. In 3 out 4 subjects, therapy allowed both...
Gluten-free diets (GFD) were considered as high glycemic index and/or content of saturated fats; this could affect keeping good metabolic control in individuals with both type 1 diabetes (T1D) and celiac disease (CD). Our objective was to analyze time range other continuous glucose monitoring (CGM) metrics real-time CGM systems, youths T1D CD, compared those only.
Abstract Background Congenital Hyperinsulinism typically occurs with a neonatal hypoglycemia but can appear even in childhood or adolescence different types of glucose metabolism derangements. Current diagnostic algorithms don’t take into account cases late presentation. Patients and methods Clinical laboratory data twenty-two subjects diagnosed at Federico II University Naples have been described: patients divided according to the molecular defect channel defects, metabolic defects...
Diagnosis of systemic cat scratch disease may be challenging. Here, we describe a case an immunocompetent girl exhibiting fever and multifocal hepatosplenic abscesses. Diagnostic tests for Bartonella henselae infection (enzyme immunoassay polymerase chain reaction) were found steadily negative the diagnosis, suspected on basis Margilet's criteria, was finally confirmed by indirect immunofluorescent antibodies.
ResultsThe 43 participants enrolled were aged 7 to 16 years (median, 12 years; IQR, 9-13 years), of whom 23 (53.5%) girls.The duration diabetes ranged from 2 13 6 4-9
Abstract “Blueberry muffin baby” is an expression applied to newborns displaying a generalized purpuric rash caused by dermal erythropoiesis. This presentation typically associated with TORCH (toxoplasmosis, other, rubella, cytomegalovirus, and herpesvirus) complex infections. However, alternative diagnoses should be considered, including other infections, neoplastic diseases, congenital vascular lesions, metabolic diseases. We report case of perinatal‐lethal‐type Gaucher disease presenting...