A5054618880- Diabetes Management and Research
- Pancreatic function and diabetes
- Diabetes and associated disorders
- Eating Disorders and Behaviors
- Obesity, Physical Activity, Diet
- Health and Lifestyle Studies
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Diabetes Treatment and Management
- Urological Disorders and Treatments
- COVID-19 and Mental Health
- Pediatric Urology and Nephrology Studies
- Diet, Metabolism, and Disease
- Metabolism, Diabetes, and Cancer
- Genomics and Rare Diseases
- Healthcare professionals’ stress and burnout
- Chronic Kidney Disease and Diabetes
- Patient-Provider Communication in Healthcare
- Chemotherapy-related skin toxicity
- Helicobacter pylori-related gastroenterology studies
- Psychological Treatments and Disorders
- Endoplasmic Reticulum Stress and Disease
- Congenital heart defects research
- Pharmaceutical studies and practices
- Kidney Stones and Urolithiasis Treatments
- Digestive system and related health
University of Campania "Luigi Vanvitelli"
2007-2024
Hospital de Clínicas de Porto Alegre
2024
University of Naples Federico II
2007-2016
Federico II University Hospital
2005
Acute kidney injury (AKI) and renal tubular damage (RTD), especially if complicated by acute necrosis (ATN), could increase the risk of later chronic disease. No prospective studies on AKI RTD in children with type1diabetes mellitus (T1DM) onset are available.To evaluate prevalence their rate timing recovery T1DM onset.Prospective study.185 were followed up after 14 days from onset. The patients who did not recover AKI/RTD followed-up 30 60 later.AKI was defined according to KDIGO criteria....
The association between Type 1 Diabetes Mellitus (T1DM) and obesity (Ob) is no longer unexpected due to unhealthy lifestyle mostly in adolescents. We compared clinical-biochemical characteristics, adherence the Mediterranean Diet (MD), habits physical fitness across different weight categories of T1DM adolescents from Campania Region. As second aim, we assessed relationship among these patients.74 (35M; 39F; 13-18 y), with diagnosed at least 6 mo before study, were enrolled Regional Center...
Aim/Hypothesis To compare the frequency of diabetic ketoacidosis (DKA) at diagnosis type 1 diabetes in Italy during COVID-19 pandemic 2020 with DKA 2017-2019. Methods Forty-seven pediatric centers caring for >90% young people recruited 4,237 newly diagnosed children between 2017 and a longitudinal study. Four subperiods were defined based on government-imposed containment measures COVID-19, frequencies severe compared same periods Results Overall, increased from 35.7% (95%CI,...
To examine body image problems and their associations with disordered eating behavior in adolescents type 1 diabetes well-matched healthy peers.Using a cross-sectional design, 183 (13.02-18.05 years) were recruited from centers southern Italy compared to peers matched for age gender. Participants completed self-report measures of behaviors (DEPS-r EDI-3RF) gender-specific problem questionnaire (SATAQ-4R). Socio-demographic clinical data (zBMI, HbA1c, disease duration) also collected....
Objective Transient neonatal diabetes mellitus (TNDM) is caused by activating mutations in ABCC8 and KCNJ11 genes (K ATP /TNDM) or chromosome 6q24 abnormalities (6q24/TNDM). We wanted to assess whether these different genetic aetiologies result distinct clinical features. Design Retrospective analysis of the Italian data set patients with TNDM. Methods Clinical features treatment 22 K /TNDM 12 6q24/TNDM were compared. Results Fourteen probands had a carrier parent abnormal glucose values,...
Abstract Background Given that the widely acknowledged influence of doctor-patient relationship on objective health parameters and treatment adherence in chronic illnesses, this study sought to explore how patients perceived patient-doctor across virtual in-person contexts. Methods Parents’ patients’ perceptions were evaluated 610 children adolescents (12.17 ± 4.19 years, 50.9% girls) with type 1 diabetes who visited via video-conferencing or person during COVID-19 pandemic. Results No...
Skin reactions due to technological devices pose a significant concern in the management of type 1 diabetes (T1D). This multicentric, comparative cross-sectional study aimed assess psychological impact device-related skin issues on youths with T1D and their parents.
Recent research indicates that patients with type 1 diabetes (T1D) are at higher risk for disordered eating behaviors (DEBs) than their peers without diabetes. The present study aimed to explore the prevalence of DEBs in a sample Italian children and adolescents T1D matched-pair healthy controls during COVID-19 lockdown.In cross-sectional study, 138 (aged 8.01-19.11 years, 65 boys) attending Southern diabetic service 276 age- gender-matched voluntarily completed an online survey about (ChEAT...
The aim of this study was to report nationwide data the prevalence disordered eating behaviors (DEBs) in adolescents with type 1 diabetes (T1D) and evaluate a multidimensional model problems, analyzing how psychopathological problems are associated DEBs metabolic control.This carried out using cross-sectional design sample 1,562 patients T1D (812 male), aged 11-19 years. Participants were recruited from multiple pediatric centers (N = 30) located northern, central, southern Italy, they...
Type 1 diabetes mellitus (DM) is characterized by irreversible, autoimmune, pancreatic β -cell destruction. During the disease, some patients experience a phase of Partial Clinical Remission (PCR) known as “ honeymoon .” This transitory period that insulin production residual cells following DM diagnosis and initiating therapy. In this study, we aimed to evaluate influence on immune system after onset diabetes, showed duration could be related other autoimmune conditions. For retrospective...
Choosing the right infusion set site can be an important factor in obtaining good glycemic control, especially very young children. In attempt to identify best site, we performed a crossover study six preschool children with type 1 diabetes using insulin pump therapy.We enrolled patients 5.2±0.7 years old (range, 4-6 years), for more than 1.5 years, therapy at least 6 months. For each patient, body mass index, glycated hemoglobin, and all data downloaded from system were evaluated on two...
To investigate fear of hypoglycemia (FoH) in parents children with type 1 diabetes (T1D) before and after undergoing training to learn intranasal (IN) glucagon administration.
Background: Glycemia following pizza consumption is typically managed with a dual-wave insulin bolus. This study evaluated the effect of simple bolus on glycemia traditionally prepared pizzas long (24 h) or short (8 dough fermentation periods. Research Design and Methods: On two separate evenings, children type 1 diabetes (n = 38) receiving sensor-integrated pump therapy consumed either (pizza A) B) fermentation, blood glucose was monitored over 11 h. A administered 15 min preprandially. The...
To evaluate (i) the prevalence and association of euthyroid sick syndrome (ESS) [decreased FT3 and/or FT4 normal/decreased TSH] with severity indexes type 1 diabetes mellitus (T1DM) onset such as diabetic ketoacidosis (DKA) kidney damage [acute injury (AKI) based on KDIGO criteria, acute tubular necrosis (ATN), renal (RTD)], (ii) relationship between clinical/metabolic parameters at T1DM thyroid hormones, (iii) ESS a prognostic indicator delayed recovery from damage.A total 161 children were...
Pandemics are states of disease that occur worldwide and sharply increase in populations. It causes life events which trigger anxiety, depression, anger, sleep deprivation, emotional distress stress. World Health Organization (WHO) declared coronavirus 2019 (COVID-19) a pandemic on March 11, pointing to the over 118,000 cases 110 countries. Many healthcare workers became ill during some among them died. In this study, we aimed evaluate compare level stress against COVID-19 doctors from...
Abstract Introduction/Objective Pancreatic and duodenal homeobox 1 (PDX1) is a well-studied transcription factor required for pancreas organogenesis. PDX1 mutations are associated with the development of diabetes. An 8-month-old female patient previously uncharacterized compound heterogeneous missense (Thr151Met Asn196Thr) was identified in this study. The has permanent neonatal diabetes, hypoplasia, malformed gallbladder. Methods/Case Report Thr151Met Asn196Thr variants were by...
Abstract Background Parenteral nutrition (PN) provides to patients who cannot use the digestive tract. Some experience delayed appetite recovery after PN, but factors contributing this remain unclear. This study aimed investigate whether hospitalized receiving PN reduced hunger or appetite. Methods A descriptive cohort was conducted on adults underwent between April 2022 and July 2023. Data patient characteristics nutritional support were collected from medical records. Hunger satiety...