A5048870984- Drug Transport and Resistance Mechanisms
- Protein Interaction Studies and Fluorescence Analysis
- Diabetes Management and Research
- Metal complexes synthesis and properties
- Diabetes and associated disorders
- Posttraumatic Stress Disorder Research
- Pancreatic function and diabetes
- Medicine, History, and Philosophy
- COVID-19 and Mental Health
- Healthcare professionals’ stress and burnout
Hacettepe University
2020-2024
Type 1 diabetes mellitus (DM) is characterized by irreversible, autoimmune, pancreatic β -cell destruction. During the disease, some patients experience a phase of Partial Clinical Remission (PCR) known as “ honeymoon .” This transitory period that insulin production residual cells following DM diagnosis and initiating therapy. In this study, we aimed to evaluate influence on immune system after onset diabetes, showed duration could be related other autoimmune conditions. For retrospective...
Abstract A novel carbazole compound, named 1-(9-ethyl-9H-carbazol-3-yl)-3-phenylurea ( Cpu) was synthesized and its binding properties with protease enzymes (pepsin trypsin) has been examined by steady-state fluorescence measurements, UV/vis absorption, infrared (FT-IR) circular dicroism (CD) spectroscopies also computational methods. The experimental results indicated that the quenching mechanism of enzyme Cpu is static process. thermodynamic parameters (both negative ΔH/ΔS) molecular...
Pandemics are states of disease that occur worldwide and sharply increase in populations. It causes life events which trigger anxiety, depression, anger, sleep deprivation, emotional distress stress. World Health Organization (WHO) declared coronavirus 2019 (COVID-19) a pandemic on March 11, pointing to the over 118,000 cases 110 countries. Many healthcare workers became ill during some among them died. In this study, we aimed evaluate compare level stress against COVID-19 doctors from...
<title>Abstract</title> <bold>Purpose: </bold>Some studies discuss the seasonality of T1DM, none them evaluate this relationship based on severity immune response.We aimed to elucidate role autoimmunity and environmental factors in etiology DM. <bold>Methods: </bold>The study population includes 2954 patients diagnosed with T1DM between 1981-2022. We evaluated seasonal incidence other common autoimmune diseases according age diagnosis. <bold>Results</bold>: The majority only DM were born...