Mahesh Ramanan
A5076620560- Sepsis Diagnosis and Treatment
- Intensive Care Unit Cognitive Disorders
- Family and Patient Care in Intensive Care Units
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac Arrest and Resuscitation
- Renal function and acid-base balance
- Respiratory Support and Mechanisms
- COVID-19 and healthcare impacts
- Diabetes and associated disorders
- COVID-19 Clinical Research Studies
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Hemodynamic Monitoring and Therapy
- Electrolyte and hormonal disorders
- Diet and metabolism studies
- Nosocomial Infections in ICU
- Acute Kidney Injury Research
- Frailty in Older Adults
- Antibiotics Pharmacokinetics and Efficacy
- Climate Change and Health Impacts
- Parathyroid Disorders and Treatments
- Emergency and Acute Care Studies
- Antibiotic Use and Resistance
- Meta-analysis and systematic reviews
- Long-Term Effects of COVID-19
- Central Venous Catheters and Hemodialysis
UNSW Sydney
2020-2025
The University of Queensland
2015-2025
Prince Charles Hospital
2018-2025
The George Institute for Global Health
2018-2025
Queensland University of Technology
2024-2025
Queensland Health
2022-2025
Royal Brisbane and Women's Hospital
2015-2025
Mayne Pharma (Australia)
2024-2025
Lifeline Hospital
2020-2024
Queensland Centre for Mental Health Research
2024
The Acute Disease Quality Initiative (ADQI) Workgroup recently released a consensus definition of sepsis-associated acute kidney injury (SA-AKI), combining Sepsis-3 and Kidney Improving Global Outcomes (KDIGO) AKI criteria. This study aims to describe the epidemiology SA-AKI.This is retrospective cohort carried out in 12 intensive care units (ICUs) from 2015 2021. We studied incidence, patient characteristics, timing, trajectory, treatment, associated outcomes SA-AKI based on ADQI...
Importance Whether β-lactam antibiotics administered by continuous compared with intermittent infusion reduces the risk of death in patients sepsis is uncertain. Objective To evaluate whether vs a antibiotic (piperacillin-tazobactam or meropenem) results decreased all-cause mortality at 90 days critically ill sepsis. Design, Setting, and Participants An international, open-label, randomized clinical trial conducted 104 intensive care units (ICUs) Australia, Belgium, France, Malaysia, New...
Objectives To describe the characteristics and outcomes of patients with COVID-19 admitted to intensive care units (ICUs) during initial months pandemic in Australia. Design, setting Prospective, observational cohort study 77 ICUs across Participants Patients participating laboratory-confirmed 27 February – 30 June 2020. Main outcome measures ICU mortality resource use (ICU length stay, peak bed occupancy). Results The median age 204 was 63.5 years (IQR, 53–72 years); 140 were men (69%)....
Abstract Background The study aimed to describe the epidemiology and outcomes of hospital-acquired bloodstream infections (HABSIs) between COVID-19 non-COVID-19 critically ill patients. Methods We used data from Eurobact II study, a prospective observational multicontinental cohort on HABSI treated in ICU. For current analysis, we selected centers that included both performed descriptive statistics terms patients’ characteristics, source infection microorganism distribution. studied...
Objective To compare the demographic and clinical features, management, outcomes for patients admitted with COVID-19 to intensive care units (ICUs) during first, second, third waves of pandemic in Australia. Design, setting, participants People aged 16 years or more polymerase chain reaction-confirmed 78 Australian ICUs participating Short Period Incidence Study Severe Acute Respiratory Infection (SPRINT-SARI) Australia project first (27 February – 30 June 2020), second (1 July 2020 25...
Abstract Background Our understanding of post-ICU recovery is influenced by which patients are selected to study and treat. Many studies currently list an ICU length stay at least 24, 48, or 72 h as inclusion criterion. This may be driven established evidence that prolonged time in bed ventilation can complicate rehabilitation. However, after short stays still needs explored. Methods a secondary analysis from the tracking outcomes post-intensive care (TOPIC) study. One hundred thirty-two...
In recent years, numerous dosing studies have been conducted to optimize therapeutic antibiotic exposures in patients with serious infections. These led the inclusion of dose optimization recommendations international clinical practice guidelines. The last survey describing dosing, administration and monitoring commonly prescribed antibiotics for critically ill was published 2015 (ADMIN-ICU 2015). This study aimed describe evolution since this time.
Background Traumatic brain injury (TBI) is common and a leading cause of presentations to emergency departments. Understanding the epidemiology TBI can aid in improving overall management identifying opportunities for prevention. Currently, there paucity data on paediatric NSW. The purpose this study was determine demographics, causes, treatment outcome at Children's Hospital Westmead (CHW), large trauma referral hospital. Methods A retrospective chart review conducted patients admitted CHW...
Background: Italy was the first Western country to be heavily affected by COVID-19. Healthcare workers (HCWs) were exposed a high risk of occupational infection, partially due insufficient personal protective equipment (PPE) supplies. This study aimed describe practices, availability, training, confidence in PPE use and adverse effects extended use, as reported HCWs Italy. We also provide comparison between Italian data those from other countries. Methods: secondary analysis previously...
Abstract Background The use of extracorporeal membrane oxygenation (ECPR) in refractory out-of-hospital cardiac arrest (OHCA) patients is usually implemented in-hospital. As survival ECPR critically time-dependent, alternative models delivery could improve equity access. Objectives To identify the best strategy to provide optimal patient access, examine time-sensitivity on predicted and model potential benefits from different strategies ECPR. Methods We used transport accessibility...