A5017342478- Pleural and Pulmonary Diseases
- Lung Cancer Diagnosis and Treatment
- Airway Management and Intubation Techniques
- Respiratory Support and Mechanisms
- Pneumothorax, Barotrauma, Emphysema
- Cancer, Stress, Anesthesia, and Immune Response
- Trauma Management and Diagnosis
- Myasthenia Gravis and Thymoma
- Breast Cancer Treatment Studies
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Breast Implant and Reconstruction
- Breast Lesions and Carcinomas
- Inflammatory Biomarkers in Disease Prognosis
- Congenital Diaphragmatic Hernia Studies
- Medical Imaging and Pathology Studies
- Ultrasound in Clinical Applications
- Anesthesia and Pain Management
- Parkinson's Disease and Spinal Disorders
- Enhanced Recovery After Surgery
- COVID-19 and healthcare impacts
- Hepatocellular Carcinoma Treatment and Prognosis
- Venous Thromboembolism Diagnosis and Management
- Cancer Diagnosis and Treatment
- Reconstructive Surgery and Microvascular Techniques
- Pituitary Gland Disorders and Treatments
University of Rome Tor Vergata
2009-2025
Policlinico Tor Vergata
2011-2024
El.En. Group (Italy)
2011
NorthEast Regional Epilepsy Group
2008
Park Terrace Care Center
2007
This study was undertaken to assess stress hormones response after awake videoassisted thoracoscopic surgery (VATS). Plasma levels of adrenal-corticotropic hormone (ACTH), cortisol, epinephrine, norepinephrine, and glucose were assessed at baseline, 3 h postoperatively (T1), on postoperative mornings 2 (T2) (T3) in 21 patients undergoing VATS with epidural anesthesia for non-malignant conditions (n=11) or equivalent procedures performed general anesthesia. Epinephrine level peaked both...
Objective: To evaluate feasibility, technical features and results of video-assisted pleural decortication for empyema thoracis performed in awake patients. Methods: This retrospective analysis involved a cohort 19 patients (median age: 58 years) undergoing thoracoscopic under epidural anaesthesia (N = 15) or paravertebral blocks 4) between March 2004 September 2008. Baseline perioperative data including degree postoperative lung re-expansion at 48 h, hospital stay, morbidity rate daily...
Despite advancements in breast cancer surgery, the decision-making process for axillary treatment remains complex, necessitating new predictors like tumor size to Ki67 proliferation index ratio. Intraoperative examination of sentinel lymph node is performed reduce risk a secondary surgery. Several studies have demonstrated that even presence moderate nodal involvement, local disease control can be achieved by omitting dissection (ALND). The aim our retrospective study compare patients...
Thoracoscopic thymectomy has shown promise in the integrated management of myasthenia gravis (MG) although there is still scant data on long-term results. The aim this study was to analyze (>5 years) results thoracoscopic extended nonthymomatous MG.We retrospectively reviewed 32 patients operated between 1995 and 2003. MG foundation America clinical classification (MGFA), symptoms' duration, preoperative crisis, anticholinesterase-drugs dosage, steroid use, acetylcholine receptor antibodies...
Objective: In a prospective non-randomized study, we compared results and costs of non-resectional lung volume reduction surgery (LVRS) performed through awake or non-awake anesthesia that was freely chosen by recruited patients. Method: Non-resectional LVRS epidural in 41 patients (awake group) general 19 (non-awake group). Perioperative outcome included analysis oxygenation (PaO2/FiO2) at fixed time points global spent the operating room (anesthesia plus weaning recovery times). Costs were...
Malignant pleural effusion can be treated successfully by video-assisted thoracic surgery (VATS) talc pleurodesis. This procedure also performed using local anesthesia on nonintubated patients.To evaluate quality of life and major outcomes after VATS pleurodesis under in patients with malignant effusion.Retrospective, nonrandomized case-matched comparison (nonintubated versus intubated) pairing the computer according to their clinical features.Since 2002, 231 consecutive underwent uniport...
Background: Surgical stress and anesthesia affect the patient9s immune system. Analysis of lymphocyte response after breast-conserving surgery was conducted to investigate differences between effects general local anesthesia. Materials Methods: Fifty-six patients with breast cancer were enrolled for BCS through or Total leukocytes, total lymphocytes, lymphocyte-subsets including CD3<sup>+</sup>, CD19<sup>+</sup>, CD4<sup>+</sup>, CD8<sup>+</sup>, CD16<sup>+</sup>CD56<sup>+</sup>...
Objective: Staple excision of emphysematous bullae through general anesthesia is the standard surgical treatment bullous emphysema. We have developed a new technique entailing thoracoscopic bullaplasty performed in fully awake patients sole epidural anesthesia. Methods: This prospective nonrandomized trial included 35 undergoing between 2002 and 2009. Preoperative work-up computed tomography with algorithm for quantitative measurement bulla volume. Outcome measures patient's satisfaction...
The current surgical guidelines recommend an optimal margin width of 2 mm for the management patients diagnosed with ductal carcinoma in situ (DCIS). However, there are still many controversies regarding re-excision when criteria not met first resection. purpose this study is to understand importance width, re-excision, and treatments avoid additional surgery on locoregional recurrence (LRR). retrospective analyzed margins, adjuvant treatments, LRR DCIS who underwent breast-conserving (BCS)....
Objective: Prolonged air leak occurs frequently after lung volume reduction surgery (LVRS) and can negatively affect both morbidity hospital stay. We hypothesised that awake nonresectional LVRS could reduce the duration of in emphysema patients. Methods: This analysis included 66 patients undergoing awake, unilateral plication most emphysematous regions under sole epidural anaesthesia. Primary outcome measure was rate prolonged (>7 days) leak; secondary measures mean leak, stay early...
Background: Unexpected spread to regional lymph nodes can be found in up 10% of patients with early stage non-small cell lung cancer (NSCLC), thereby affecting both prognosis and treatment. Given the known relation between systemic inflammation tumor progression, we sought evaluate whether blood-derived markers might help predict nodal outcome Ia NSCLC. Methods: Preoperative levels neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte (PLR), score (SII, platelets × NLR) were collected...
Background: Resection of additional tissue circumferentially around the cavity left by lumpectomy (cavity shave) was suggested to reduce rates positive margins and re-excision. Methods: A single center retrospective study which analyzed status, re-excision, surgical time in patients who underwent breast conserving surgery shave or intraoperative evaluation resection margins. Results: Between 2021 2023, 594 were enrolled study. In subjected shave, a significant reduction positive, focally...
Background/Aim: In the context of surgical de-escalation in early breast cancer (EBC), this study aimed to evaluate contrast enhancement ultrasound (CEUS) sentinel lymph node (SLN) procedure as a non-invasive axillary staging EBC comparison with standard SLN biopsy (SLNB). Patients and Methods: A subanalysis AX-CES study, prospective single-arm, monocentric phase 3 was performed (EudraCT: 2020-000393-20). The included patients undergoing upfront surgery resection, no prior history...
In this study, we investigated role and results of multi-reoperations for lung metastases. From 1986 to 2010, 113 consecutive patients (61 men 52 women; mean age: 53.2 ± 12.8 years) underwent repeated metastasectomy with curative intent in our institution. Two procedures were performed patients, three 54, four 31, five eight six three. There was no perioperative mortality. Cumulative 5-year survival 65% significantly higher than the value recorded undergoing only one (42%; p = 0.021). Size,...