A5075034226- Traumatic Brain Injury and Neurovascular Disturbances
- Acute Ischemic Stroke Management
- Cerebrospinal fluid and hydrocephalus
- Intracerebral and Subarachnoid Hemorrhage Research
- Optical Imaging and Spectroscopy Techniques
- Cerebral Venous Sinus Thrombosis
- Spaceflight effects on biology
- Mechanical Circulatory Support Devices
- Neurosurgical Procedures and Complications
- Organ Donation and Transplantation
- Patient Safety and Medication Errors
- Hemodynamic Monitoring and Therapy
- Cardiac Arrest and Resuscitation
- Sepsis Diagnosis and Treatment
- Photoacoustic and Ultrasonic Imaging
- Ultrasound in Clinical Applications
- Spinal Fractures and Fixation Techniques
- Medical Imaging and Analysis
- Facial Trauma and Fracture Management
- Surgical Simulation and Training
- Autoimmune and Inflammatory Disorders
- Chronic Lymphocytic Leukemia Research
- Urban Green Space and Health
- Respiratory Support and Mechanisms
- Injury Epidemiology and Prevention
Baylor College of Medicine
2020-2025
Rice University
2024
Baylor University Medical Center
2023
Ochsner Medical Center
2022
University of Pittsburgh
2020
The University of Texas Health Science Center at Houston
2016
Human spaceflight has historically been managed by government agencies, such as in the NASA Twins Study
A patient presented with fever, generalised rash, confusion, orofacial movements and myoclonus after receiving the first dose of mRNA-1273 vaccine from Moderna. MRI was unremarkable while cerebrospinal fluid showed leucocytosis lymphocyte predominance hyperproteinorrachia. The skin evidenced red, non-scaly, oedematous papules coalescing into plaques scattered non-follicular pustules. Skin biopsy consistent a neutrophilic dermatosis. fulfilled criteria for Sweet syndrome. thorough evaluation...
To standardize optic nerve sheath diameter (ONSD) point-of-care ultrasonography (POCUS) and improve its research clinical utility by developing the ONSD POCUS Quality Criteria Checklist (ONSD QCC).
Virtual reality (VR) and augmented (AR) are rapidly developing technologies that may have important healthcare-related applications, including the possible evaluation of health performance astronauts. Advances in fields VR/AR space exploration independently progressed; however, over last decade synergies overlapping applications emerged between spaceflight extended reality. This paper is intended to be a resource update medical community on current future integration VR AR into exploration,...
Abstract Background Numerous trials have addressed intracranial pressure (ICP) management in neurocritical care. However, identifying its harmful thresholds and controlling ICP remain challenging terms of improving outcomes. Evidence suggests that an individualized approach is necessary for establishing tolerance limits ICP, incorporating factors such as waveform (ICPW) or pulse morphology along with additional data provided by other invasive (e.g., brain oximetry) noninvasive monitoring...
Abstract Background and Purpose The optic nerve is surrounded by the extension of meningeal coverings brain. When pressure in cerebrospinal fluid increases, it causes a distention sheath diameter (ONSD), which allows use this measurement ultrasonography (US) as noninvasive surrogate elevated intracranial pressure. However, ONSD measurements literature have exhibited significant heterogeneity, suggesting need for consensus on image acquisition measurement. We aim to establish an US Quality...
Ultrasonographic optic nerve sheath diameter (ONSD) is a non‐invasive intracranial pressure (ICP) surrogate. This article discusses the effect of ultrasound settings and imaging artifacts on ONSD assessment. Ultrasound that may affect assessment include gain, dynamic range, frequency, harmonic imaging, focal zones. Artifacts can be related to imaged structures (acoustic shadowing, enhancement, comet tail, speckle artifacts) or beam properties (partial volume refraction artifacts). In...
Intracranial pressure (ICP) measures the exerted by fluids and tissues inside skull, typically 7-15mmHg for healthy adults. Conditions such as traumatic brain injury, hydrocephalus, intracranial hemorrhage often cause elevated ICP $(\gt 20$ mmHg), which is life-threatening requires immediate medical interventions. These conditions also lead to changes in waveform morphology, especially an increased P2/P1 amplitude ratio, reflecting compromised cerebral compliance [1] (Fig. 17.11.1, top...
Preventing secondary brain injury after neurological insults is one of the primary goals neurocritical care unit. Our understanding roles intracranial pressure (ICP) and cerebral edema in managing patients units still evolving. Recent clinical trials examining monitoring treatment elevated ICP have influenced way we think about hypertension. Additionally, new methods ICP, physiologic surrogates derived from measurements, evolving technology to measure are currently being studied tested for...
Abstract Background and purpose Ultrasonographic optic nerve sheath (ONS) diameter is a noninvasive intracranial pressure (ICP) surrogate. ICP monitored invasively in specialized intensive care units. Noninvasive monitoring important less settings. However, using ONS (ONSD) limited by the need for experts to obtain perform measurements. We aim automate ONSD measurements deep convolutional neural network (CNN) with novel masking technique. Methods trained CNN reproduce masks that mark ONS....
To test the hypothesis that optic nerve sheath diameter (ONSD) correlates with real-time changes in intracranial pressure, we performed ultrasound measurements of ONSD ambulatory patients undergoing elective lumbar puncture (LP). We conducted a prospective cohort study, including adult LP non-emergent setting. measured perpendicular to at 3 mm behind globe both eyes traverse and sagittal planes, patient supine. The primary outcome was change from pre-LP post-LP. calculated association...
We evaluated the impact of a simulation-based brain death determination workshop among second-year neurology residents, focusing on foundational understanding as well their proficiency conducting examinations.
To develop an automated AI based segmentation and annotation method capable of selecting ultrasound images suitable for measurement performing optic nerve sheath diameter (ONSD) measurements which are comparable to the ones obtained by experienced physicians.
This paper presents a 9-mW ultrasonic through-transmission transceiver (TRX) for portable, non-invasive intracranial pressure (ICP) sensing. It employs two ultrasound transducers placed at the temporal bone windows to measure changes in time-of-flight (ToF), based on which skull expansion and corresponding ICP waveform are derived. Key components include high-efficiency Class-DE power amplifier (PA) with 95% efficiency an output swing of 15.8 VPP, along successive approximation register...