A5004759306- Salivary Gland Disorders and Functions
- Systemic Lupus Erythematosus Research
- COVID-19 Clinical Research Studies
- Renal Diseases and Glomerulopathies
- Long-Term Effects of COVID-19
- Salivary Gland Tumors Diagnosis and Treatment
- Autoimmune and Inflammatory Disorders Research
- COVID-19 and Mental Health
- Vasculitis and related conditions
- Immunodeficiency and Autoimmune Disorders
- Growth Hormone and Insulin-like Growth Factors
- Pharmacological Effects of Natural Compounds
- Dermatological and COVID-19 studies
- COVID-19 and healthcare impacts
- Hematological disorders and diagnostics
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Hair Growth and Disorders
- Liver Disease Diagnosis and Treatment
- Healthcare Systems and Technology
- Systemic Sclerosis and Related Diseases
- Cervical Cancer and HPV Research
- Dermatology and Skin Diseases
- Lymphatic System and Diseases
- Herpesvirus Infections and Treatments
Universidade Federal da Paraíba
2014-2025
Hospital Universitário Lauro Wanderley
2015-2021
John Wiley & Sons (United States)
2019
Michigan State University
2019
Hudson Institute
2019
Sjogren's Syndrome (SS) is an autoimmune disease characterized by lymphocytic infiltration of the exocrine glands and other organs, associated with sicca syndrome but also systemic involvement varying degrees severity. Despite their importance, these manifestations are not routinely evaluated there no homogenous approach to diagnosis or evaluation. To close this gap, a panel experts from Brazilian Society Rheumatology conducted systematic review meta-analysis on identification epidemiologic...
Objective : To report the experience in three Brazilian institutions with use of rituximab patients different clinical forms lupus erythematosus systemic activity. Methods The study consisted a sample 17 LES, who were already being treated, but that at some stage disease showed refractory symptoms. subdivided into groups according to manifestation, and responses for rated as complete, partial or no response. Data collected through spreadsheet, used specific parameters each group. treatment...
Abstract Sjogren’s disease (SjD) is an autoimmune that characterized not only by the sicca symptoms it causes but also its systemic nature, which capable of several and yet fully understood extraglandular manifestations. To gain a clearer understanding these manifestations as well better practical approach, panel experts from Brazilian Society Rheumatology conducted systematic review meta-analysis on identification epidemiologic clinical features present in ESSDAI (EULAR Sjogren´s syndrome...
Abstract Background There is a lack of information on the role chronic use hydroxychloroquine during SARS-CoV-2 outbreak. Our aim was to compare occurrence COVID-19 between rheumatic disease patients with individuals from same household not taking drug first 8 weeks community viral transmission in Brazil. Methods This baseline cross-sectional analysis part 24-week observational multi-center study involving 22 Brazilian academic outpatient centers. All regarding symptoms, epidemiological,...
The greater understanding of pathophysiology and behavior systemic vasculitis, together with the development therapeutic regimens increasingly better safety efficacy profiles, dramatically changed prognosis patients diagnosed these clinical entities. Recently, use rituximab in treatment ANCA-associated vasculitis randomized trials showed an important alternative selected cases, especially refractory or intolerant to standard therapy cyclophosphamide corticosteroids. This article presents...
<title>Abstract</title> <bold>Introduction:</bold> The prevalence of Fibromyalgia in patients with Systemic Lupus Erythematosus (SLE) is significantly higher compared to the general population. Despite this frequent association, remains underdiagnosed and con- sequently inadequately treated, negatively affecting quality life these patients. Objective: This study aims evaluate occurrence Fibromyal- gia its impact on Brazilian SLE treated at a University Hospital state Paraiba. <bold>Materials...
Abstract Introduction The prevalence of Fibromyalgia in patients with Systemic Lupus Erythematosus (SLE) is significantly higher compared to the general population. Despite this frequent association, remains underdiagnosed and consequently inadequately treated, negatively affecting quality life these patients. Objective This study aims evaluate occurrence its impact on Brazilian SLE treated at a University Hospital state Paraiba. Materials methods descriptive, observational, cross-sectional...
During the COVID-19 pandemic, undergraduate medical students (UMS) exposed to isolation, social distancing and complete or partial face-to-face educational activities interruption may present increased stress, depression anxiety. This study was undertaken evaluate if, during UMS involved in online group as investigators of a research project (volunteer group) would better mental health than their colleagues, not that (control group). A Web-based survey, via Google Forms platform, including...
Systemic lupus erythematosus (SLE) is an autoimmune, inflammatory, chronic, disease of indefinite etiology, which allied to the presence autoantibodies responsible for a large number clinical spectra. Cardiac involvement in SLE occurs about 50% cases, being pericarditis most frequent. Myocarditis 8-10% patients and may be due multiple causes, association with activity frequent, followed by ischemia atherosclerosis valvular dysfunction.
Rheumatoid Arthritis (RA) is a chronic inflammatory disease that results from the complex interaction between genetic and environmental factors, associated with high risk of viral infection, especially during immunobiological use. Tocilizumab effective in treating this by limiting multiple proinflammatory activities IL-6 inhibiting its gp130 receptor. Studies mice deficient demonstrated susceptibility to Herpes Zoster since presence cytokine necessary for good immune response after infection...
BACKGROUNDLupus nephritis is one of the major complications in systemic lupus erythematosus (SLE), whereas it main factor morbimortality.Depletion B lymphocytes has been a new therapeutic option for patients who are refractory to conventional treatments schemes.
The coronavirus disease 2019 (COVID-19) pandemic has brought additional burden to patients living with immune-mediated rheumatic diseases (IMRDs), especially at the beginning of 2020, for which information this population is lacking.COnVIDa a cross-sectional study on IMRD from all regions Brazil who were invited answer specific and customized Web questionnaire about how they facing COVID-19 pandemic, focusing health care access, use medications, patient-reported outcomes related activity....
BACKGROUNDTo evaluate the clinical and laboratory profiles of patients with lupus erythematosus (LE) cutaneous manifestations who were followed up in dermatology rheumatology outpatient clinics a tertiary hospital.