A5035644708- Prostate Cancer Treatment and Research
- Renal cell carcinoma treatment
- Bladder and Urothelial Cancer Treatments
- Urinary and Genital Oncology Studies
- Cancer, Lipids, and Metabolism
- Kidney Stones and Urolithiasis Treatments
- Pediatric Urology and Nephrology Studies
- Urological Disorders and Treatments
- Renal and related cancers
- Hormonal and reproductive studies
- Sperm and Testicular Function
- Ovarian cancer diagnosis and treatment
- Multiple and Secondary Primary Cancers
- Nutrition, Genetics, and Disease
- Cancer Diagnosis and Treatment
- Prostate Cancer Diagnosis and Treatment
- Reproductive Biology and Fertility
- Economic and Financial Impacts of Cancer
- Epigenetics and DNA Methylation
- Cancer-related molecular mechanisms research
- Advanced Breast Cancer Therapies
- Protease and Inhibitor Mechanisms
- Protein Hydrolysis and Bioactive Peptides
- Testicular diseases and treatments
- Cardiac tumors and thrombi
Semmelweis University
2011-2024
University of Debrecen
2008-2024
BM Központi Kórház
2009
National Institute of Oncology
2004
University of Pecs
2001
Article24 June 2019Open Access Source DataTransparent process Apelin inhibition prevents resistance and metastasis associated with anti-angiogenic therapy Iris Uribesalgo Corresponding Author [email protected] orcid.org/0000-0001-9492-1000 Institute of Molecular Biotechnology the Austrian Academy Sciences (IMBA), Vienna BioCenter, Vienna, Austria Search for more papers by this author David Hoffmann Yin Zhang Department Microbiology, Tumor Cell Biology, Biomedicum, Karolinska Institutet,...
To investigate the patterns of expression junctional proteins beta-catenin and claudins in different prognostic groups patients with prostatic cancer, to determine their value as markers.We evaluated samples 30 who had a radical prostatectomy for organ-confined cancer (pT2N0M0), men clinically advanced control group benign hyperplasia. Using immunohistochemistry applied tissue microarrays, each was claudin-1, -2, -3, -4, -5, -7, -8 -10, expression.There were differences among three claudin-1...
// Attila Szendrői 1, * , A. Marcell Szász 2, Magdolna Kardos Anna-Mária Tőkés 3 Roni Idan 2 Miklós Szűcs 1 Janina Kulka Péter Nyirády 4 Zoltán Szállási 5, 6 Balázs Győrffy 7, 8 József Tímár 3, Department of Urology, Semmelweis University, Budapest 1082, Hungary 2nd Pathology, 1091, Molecular Oncology Research Group, Hungarian Academy Sciences and Orthopedics, 1113, 5 Children's Hospital Informatics Program at the Harvard-MIT Division Health Technology, Harvard Medical School, Boston, MA...
The development and progression of male infertility are closely linked to a sedentary lifestyle; however, its underlying mechanisms not fully elucidated. Our aim was assess the protective effects moderate swimming exercise on reproductive system in isoproterenol-treated rats. Male Wistar rats were divided into five groups as follows: (1) non-interventional controls (CTRL), (2) (ISO), (3) pre-treatment training + ISO (PRE ISO), (4) post-treatment (ISO+POST), (5) POST) groups. Testicular...
Urachal cancer (UrC) is a rare disease which mostly diagnosed late due to symptoms caused by its local invasion the urinary bladder. Given lack of clinical trials and guideline recommendations for systemic treatment, molecularly informed precision oncology approach viable option UrC already in early lines treatment. While single case experiences may provide valuable reference later decision-making, well-documented experience with off-label targeted treatments limited few patients. Here, we...
The relationship between overweight and male fertility is well studied, still the correlation of obesity decreased sperm quality a subject to debate. widely used conventional spermatological examinations alone seem be inadequate assess fertilization potential. Hyaluronan Binding Assay (HBA®) one available validated tests that allows functional examination sperm. Data 72 patients (mean age 33.9 (24-43) years) from infertile couples were analysed. Body Mass Index (BMI) determination, semen...
Számos közlemény beszámol tumoros betegek életminőségének javítására alkalmazott étrend-kiegészítők hatásáról, de mindezek élettani vizsgálata szegényes. A cékla számos, a szervezetben lezajló biokémiai reakcióutat, enzim- és metabolitszintézist befolyásol. Módszer: szerzők hormonrezisztens metasztatikus prosztatarák miatt taxán-kemoterápiában részesülő javítása érdekében kereskedelmi forgalomból származó természetes céklakészítményt adtak egy hónapon át 2×10 g dózisban 24 (életkor: 68±8 év)...
The COVID-19 pandemic has posed a huge challenge to the world in recent years. development of vaccines that are as effective possible and accessible society offers promising alternative for addressing problems caused by this situation soon restore pre-epidemic system. present study investigated preferences residents Hungary’s second-largest city (Debrecen) vaccine. To achieve aim, discrete choice experiment was conducted with 1011 participants, vaccine characteristics included design were...
(1) Background: In cardiovascular applications, paclitaxel inhibits smooth muscle cell proliferation and migration significantly reduces the occurrence of restenosis target lesion revascularization. However, cellular effects in myocardium are not well understood; (2) Methods: Wistar rats were divided into four groups: control (CTRL), isoproterenol (ISO) treated (1 mg/kg) two groups with (PAC), which was administrated (10 mg/kg/day) for 5 days by gavage/per os alone or combination (ISO + PAC)...
Abstract Clinical trials revealed significant antitumor activity for immune checkpoint inhibitors (ICI) in metastatic urothelial carcinoma (mUC). Due to their strict eligibility criteria, clinical include selected patient cohorts, and thus do not necessarily represent real-world population outcomes. In this multicentric, retrospective study, we investigated data assess the effectiveness of pembrolizumab atezolizumab evaluate prognostic value routinely available clinicopathological laboratory...
The aim of the study was to statistically prove that HBA® test is an efficient practical method for andrologists determine fertility potential as well measure efficiency oral supplement therapy in case male infertility. In study, 175 patients were involved and it also included follow-up studies 39 after therapy. Completing ‘classic’ spermatological parameters with results test, authors have determined a new index be used rating potential. After therapy, both sperm density hyaluronan binding...
Endogenous transmethylation processes proceed via formaldehyde.Endogenous formaldehyde can be found in special bounded forms animal tissues.The aim was to find non-invasive methods help establish an early diagnosis of prostate cancer processes, and search for a reliable examination repertoire predict metastasis based on genomic hypomethylation that tumors.Fifty-eight age-matched patients suffering from 26 healthy volunteers were enrolled the study.Biochip technique applied quantify serum...
Abstract Baseline or acquired resistance to docetaxel (DOC) represents a significant risk for patients with metastatic prostate cancer (PC). In the last years, novel therapy regimens have been approved providing reasonable alternatives DOC‐resistant making prediction of DOC great clinical importance. We aimed identify serum biomarkers, which are able select who will not benefit from treatment. PC3‐DR and DU145‐DR sublines their sensitive parental cell lines (DU145, PC3) were comparatively...