- Gut microbiota and health
- Probiotics and Fermented Foods
- Anaerobic Digestion and Biogas Production
- Water Treatment and Disinfection
- Wastewater Treatment and Nitrogen Removal
- Folate and B Vitamins Research
- Peripheral Neuropathies and Disorders
- Multiple Sclerosis Research Studies
- Legionella and Acanthamoeba research
- Diet and metabolism studies
- Mitochondrial Function and Pathology
- Helicobacter pylori-related gastroenterology studies
- Polyamine Metabolism and Applications
- Cancer Immunotherapy and Biomarkers
- Vascular anomalies and interventions
- Ocular Diseases and Behçet’s Syndrome
- Infant Nutrition and Health
- Assisted Reproductive Technology and Twin Pregnancy
- Polyomavirus and related diseases
- Phytase and its Applications
- RNA regulation and disease
- Signaling Pathways in Disease
- Microbial Metabolites in Food Biotechnology
- Brain Metastases and Treatment
- Geography and Environmental Studies
Health Canada
2012-2025
Hospitais da Universidade de Coimbra
2012-2023
Istanbul Technical University
2020
Amrita Vishwa Vidyapeetham
2020
Stevens Institute of Technology
2020
Central University of Kerala
2020
Kakatiya University
2020
Institute of Applied Science and Intelligent Systems
2020
US Forest Service
2018
University of Coimbra
2013
Environmental enrichment (EE) is commonly included as an important component of animal housing to promote well being laboratory animals; however, much remains be learned about the impact chewable forms EE on experimental outcomes in context nutritional and microbiome-related studies, whether differ between sexes. In present study, nylon chew bones (gnaw sticks, GS) were evaluated for their effects fermentation profiles, microbial community structure, cytokine profiles gastrointestinal...
Man-in-a-barrel syndrome (MBS) is a rare clinical condition in which patients present with bilateral brachial diplegia, relatively spared strength the lower limbs. This typically attributed to hypoperfusion brain injury rather than spinal pathology. We describe case of 75-year-old man who presented upper limb paresis. He had two cardiorespiratory arrests no documented neurological sequelae few years before. Imaging tests however showed severe cervical spondylotic myelopathy as most likely...
ABSTRACT Methane emissions represent a major environmental concern associated with manure management in the livestock industry. A more thorough understanding of how microbial communities function storage tanks is prerequisite for mitigating methane emissions. Identifying microorganisms that are metabolically active an important first step. Methanogenic archaea contributors to methanogenesis stored swine manure, and we investigated methanogenic populations by DNA stable isotope probing...
Journal Article Temporal change in the gut community of rats fed high amylose cornstarch is driven by endogenous urea rather than strictly on carbohydrate availability Get access M. Kalmokoff, Kalmokoff Atlantic Food and Horticulture Research Centre Agriculture Agri‐Food Canada Kentville NSCanada Correspondence Martin Centre, Canada, Kentville, NS B4N 1J5, Canada. E‐mail: martin.kalmokoff@agr.gc.ca Search for other works this author on: Oxford Academic Google Scholar B. Zwicker, Zwicker...
Greenhouse gas emissions represent a major problem associated with manure management in the livestock industry. A prerequisite to mitigate methane occurring during storage is clearer understanding of how microbial consortia involved methanogenesis function. Here, we have examined stored outdoor tanks from two different farms, at locations and depths. Physico-chemical microbiological characterization these samples indicated differences between each tank, as well within tank dependent on depth...
Inflammatory bowel disease (IBD) is a risk factor for the development of colon cancer. Environmental factors including diet and microflora influence outcome. Folate homocysteine have been associated with IBD-mediated cancer but their roles remain unclear. We used model chemically induced ulcerative colitis (dextran sodium sulphate (DSS)) or without carcinogen azoxymethane (AOM) to determine impact dietary folic acid (FA) on colonic tumours. Male mice ( n 15 per group) were fed FA-deficient...
Aims: To investigate the effect of continuous feeding antimicrobial growth promoters (tylosin or virginiamycin) on swine faecal community. Methods and Results: The study consisted two separate on-farm trials. Swine were fed rations containing tylosin (44 88 mg kg−1 feed) virginiamycin (11 22 continuously over growing/finishing phases. temporal impact community was assessed compared to nondosed control animals through anaerobic cultivation, analysis 16S rRNA gene libraries volatile fatty acid...
Assisted reproductive technologies (ART) account for 1-6% of births in developed countries. While most children conceived are healthy, increases birth and genomic imprinting defects have been reported; such abnormal outcomes attributed to underlying parental infertility and/or the ART used. Here, we assessed whether paternal genetic lifestyle factors, that associated with male affect sperm epigenome, can influence outcomes. We examined how haploinsufficiency Dnmt3L, an important co-factor...
Complementary feeding of breastfed infants with foods high in bioavailable zinc (Zn) can help meet physiological requirements for Zn. Some infant cereals contain concentrations phytic acid (PA) and calcium (Ca) that may reduce absorbable This study measured PA, Zn Ca selected sold Canada investigated the effects dietary PA at present on bioavailability rats. Male Sprague-Dawley rats (36-day old) were fed a control diet containing normal (29.1 mg/kg) (4.95 g/kg) or six test diets (n = 12/diet...
Folate and choline are interconnected metabolically. The MTHFD1 R653Q SNP is a risk factor for birth defects there concerns that deficiency may interact with this exacerbate health risks. 80–90% of women do not meet the Adequate Intake (AI) choline. objective study was to assess effects on maternal one-carbon metabolism reproductive outcomes in MTHFD1-synthetase deficient mouse (Mthfd1S), model R653Q. Mthfd1S+/+ Mthfd1S+/− females were fed control (CD) or choline-deficient diets (ChDD; 1/3...
A woman in her 60s was brought to the emergency department due a new-onset seizure. She drowsy on arrival and unable provide clinical history. had medical history of advanced endometrial cancer, for which she under therapeutic protocol pembrolizumab plus lenvatinib. Laboratorial investigations were unremarkable. The brain CT angiography provided further insight into case by detecting bilateral convexal subarachnoid haemorrhage with discrete opercular vasogenic oedema, without other...
Determining associations between intestinal bacteria and continuously measured physiological outcomes is important for understanding the bacteria-host relationship but not straightforward since abundance data (compositional data) are normally distributed. To address this issue, we developed a fully Bayesian linear regression model (BRACoD; Regression Analysis of Compositional Data) with measurements (continuous as function matrix relative bacterial abundances. Bacteria can be classified...
Matias, F.; Pereira, P.; Bonifácio, J.; Monteiro, T.; Mesquita, I.; Cunha, I. Author Information