A5064094208- Gut microbiota and health
- Microbial Metabolites in Food Biotechnology
- Food composition and properties
- Digestive system and related health
- Mycobacterium research and diagnosis
- Tea Polyphenols and Effects
- Dermatology and Skin Diseases
- Clostridium difficile and Clostridium perfringens research
- Psoriasis: Treatment and Pathogenesis
- Ferroptosis and cancer prognosis
- Autoimmune Bullous Skin Diseases
University of Manitoba
2023
Trent University
2022
Dietary fibers are plant-derived carbohydrates and associated components, that not digested within the human upper intestinal tract/gut. Traditionally they classified based on their solubility in water i.e., soluble dietary fiber (SDF) insoluble (IDF). The SDFs generally regarded as fermentable by microbiota, primarily large intestine. considered health-promoting food components have profound impacts different diseases such diabetes, cancer, cardiovascular, inflammatory bowel diseases....
Abstract Background Dietary fibres are not digested in the bowel; they fermented by microbes, typically promoting gut health. However, IBD patients have altered microbiota composition and can experience sensitivity to consumption of fibres. Our previous findings offered first mechanistic evidence that if dietary β-fructans (inulin oligofructose) microbes patients, these induce inflammation. This diet-induced inflammation could serious repercussions as chronic creates a mutagenic environment...
Abstract Background Dietary fibers are not digested in the bowel; they fermented by microbes, typically promoting gut health. However, IBD patients experience sensitivity to consumption of fibers. Our previous findings offered first mechanistic evidence demonstrating that unfermented dietary β-fructans (inulin and oligofructose) can induce pro-inflammatory cytokines altered epithelial barrier integrity a subset pediatric colonic biopsies cultured ex vivo, SYNERGY-1 (β-fructan) clinical study...