Plamena Dikarlo

ORCID: 0000-0003-3611-597X
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Research Areas
  • Gut microbiota and health
  • Mycobacterium research and diagnosis
  • Diet and metabolism studies
  • Ginseng Biological Effects and Applications
  • Evolution and Genetic Dynamics
  • Nutrition, Genetics, and Disease

Objective The carnivore diet is a ketogenic based exclusively on the consumption of food animal origin. While impact various diets gut microbiome extensively documented, effects remain unclear. To address this gap, we conducted pilot study an individual following and compared it with that subgroup healthy individuals. Methods A stool sample was collected from 32-year-old male adhering to sequenced using 16S DNA Amplicon Sequencing. results were then those three control groups possessing...

10.1530/mah-24-0006 article EN cc-by Microbiota and Host 2024-02-01

Abstract Background In gut ecosystems, there is a complex interplay of biotic and abiotic interactions that decide the overall fitness an individual. Divulging microbe-microbe microbe-host may lead to better strategies in disease management, as microbes rarely act isolation. Network inference for microbial communities often challenging task limited by both analytical assumptions well experimental approaches. Even after network topologies are obtained, identification important nodes within...

10.1186/s13099-024-00627-7 article EN cc-by Gut Pathogens 2024-07-10

The microbial ecology of Mycobacterium avium subspecies paratuberculosis infections (MAP) within the context Multiple Sclerosis (MS) is largely an unexplored topic in literature. Thus, we have characterized compositional and predicted functional differences gut microbiome between MS patients with MAP (MAP+) without (MAP-) infection. This was done exposome (through self-reported filled questionnaires), principally anthropometric sociodemographic patterns to gain understanding dynamics. 16S...

10.1038/s41598-024-74975-4 article EN cc-by Scientific Reports 2024-10-14

Abstract Background There is a growing body of evidence suggesting the role gut microbiome in aetiology Multiple sclerosis (MS) with development and progression disease as multifactorial interaction between gut, brain, immune system. At same time there also existing to link Mycobacterium avium subspecies paratuberculosis infections (MAP) MS. Whilst perturbations patients MS are well described literature, nothing known about MAP infected patients. In present study, using 16S rRNA...

10.21203/rs.3.rs-3651210/v1 preprint EN cc-by Research Square (Research Square) 2023-11-29
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