Yinru He

ORCID: 0000-0003-3615-5939
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About
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Research Areas
  • Congenital Heart Disease Studies
  • Tracheal and airway disorders
  • Computational Drug Discovery Methods
  • Alzheimer's disease research and treatments
  • Pluripotent Stem Cells Research
  • Cardiac Valve Diseases and Treatments
  • 3D Printing in Biomedical Research
  • Microbial Metabolism and Applications
  • Coronary Artery Anomalies
  • Congenital Diaphragmatic Hernia Studies
  • PARP inhibition in cancer therapy
  • Metabolism, Diabetes, and Cancer
  • Pharmacological Effects of Natural Compounds
  • Tissue Engineering and Regenerative Medicine
  • Cholinesterase and Neurodegenerative Diseases
  • Healthcare and Venom Research
  • Vascular anomalies and interventions
  • Forensic Entomology and Diptera Studies
  • Insect Utilization and Effects
  • Natural Antidiabetic Agents Studies

Guangdong Academy of Medical Sciences
2020-2025

Guangdong Provincial People's Hospital
2020-2025

Southern Medical University
2023-2024

South China Sea Institute Of Oceanology
2023-2024

Guangdong Pharmaceutical University
2019

This study aimed to evaluate the impact of direct total cavopulmonary connection (dTCPC) procedure on gut microbiome and metabolome. It also sought elucidate features microbiota community metabolic profiles in Fontan circulation. We randomly recruited 45 participants above 14 years old undergoing by typical extracardiac conduit (TCPC group, n = 15), (dTCPC 16) healthy control (control 14) our institution between May 2023 October 2023. 16S rRNA amplicon sequencing untargeted metabolites...

10.3389/fmicb.2025.1539046 article EN cc-by Frontiers in Microbiology 2025-03-14

Background: This study aims to compare the long-term outcomes and quality of survival between direct total cavopulmonary connection (dTCPC) procedure standard extracardiac conduit (ECC) in Fontan patients. Methods: A 31 participants who underwent operation with either ECC (n = 15) or dTCPC 16) at our institution were recruited May 2023 October 2023. Comprehensive evaluations included physical examinations, blood tests, targeted plasma metabolomics assays, cardiopulmonary exercise testing...

10.59958/hsf.8049 article EN The Heart Surgery Forum 2024-12-22

Housefly larvae (HL) powder was used to cure wounds centuries ago for its good nutritional and pharmacological values. At present, most of the medical studies are about crude extracts HL, while specific material basis is still unclear. We ground third-instar Musca domestica into a powder, degreasing preparing protein extract. The extract subjected enzymatic hydrolysis, hydrolysis products were identified by liquid chromatography-tandem mass spectrometry (LC-MS/MS). variety highly trusted...

10.1039/c9ra05854k article EN cc-by-nc RSC Advances 2019-01-01

Background There is a lack of evidence guiding the surgical timing selection in pulmonary atresia with ventricular septal defect. This study aims to compare long-term outcomes different initial rehabilitative ages patients defect (PAVSD). Methods From January 2011 December 2020, total 101 PAVSD undergoing surgery at our center were retrospectively reviewed. Receiver-operator characteristics curve analysis was used identify cutoff age 6.4 months and therefore classify into two groups....

10.3389/fcvm.2023.1189954 article EN cc-by Frontiers in Cardiovascular Medicine 2023-10-16

The long-term outcomes of direct total cavopulmonary connection in Fontan circulation have not been reported yet. This study aimed to compare the procedure with extracardiac conduit patients undergoing Fontan. From October 2004 August 2021, 297 operation by (n = 268) or 29) at our institution were retrospectively reviewed. propensity score-matching method was used match and groups a 1:2 ratio, yielding 23 group 40 group. in-hospital morbidity mortality similar between 2 both prematched...

10.1016/j.xjtc.2024.10.006 article EN cc-by-nc-nd JTCVS Techniques 2024-10-16
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