A5103002772- Healthcare and Venom Research
- Bone and Joint Diseases
- Neuroscience and Neuropharmacology Research
- Spine and Intervertebral Disc Pathology
- Nicotinic Acetylcholine Receptors Study
- Extracellular vesicles in disease
- Biomedical Research and Pathophysiology
- Antimicrobial Peptides and Activities
- Bone Metabolism and Diseases
- Melamine detection and toxicity
- Biochemical effects in animals
- MicroRNA in disease regulation
- Ion channel regulation and function
- dental development and anomalies
- Cellular transport and secretion
- Osteomyelitis and Bone Disorders Research
- Anaerobic Digestion and Biogas Production
- Intracerebral and Subarachnoid Hemorrhage Research
- Protein Kinase Regulation and GTPase Signaling
- Vascular Malformations Diagnosis and Treatment
- Tendon Structure and Treatment
- Pneumocystis jirovecii pneumonia detection and treatment
- Connective tissue disorders research
- Child Nutrition and Water Access
- Osteoarthritis Treatment and Mechanisms
Nanjing Health and Health Commission
2025
Renji Hospital
2020-2024
Shanghai Jiao Tong University
2014-2024
Shanghai Ninth People's Hospital
2013-2024
XinHua Hospital
2012-2023
Taizhou People's Hospital
2022
Nantong University
2022
Shaoxing University
2017-2021
Shanghai Public Security Bureau
2015
Qingdao University
2015
Histologic, immunohistochemical (IHC), and enzyme-linked immunosorbent assay analysis of the human ligamentum flavum (LF).The purpose this study was to determine level expression lysophosphatidic acid (LPA) in LF from lumbar spinal stenosis (LSS) patients analyze relationship among LPA, LPA receptors (LPARs), hypertrophy.LF hypertrophy fibrosis are important causes LSS. is involved fibrotic process multiple organ systems. Therefore, we hypothesized that its might also play a role...
Hypertrophic ligamentum flavum (LF) is a major cause of lumbar spinal stenosis. Our previous work showed that high levels lysophosphatidic acid (LPA) expression are positively correlated with LF hypertrophy. This study aimed to further unveil how LPA regulates hypertrophy Methods: We studied LPAR1 in human cells using PCR and western blotting. Cell viability cell cycle, apoptosis rate molecular mechanisms were assayed knockdown or overexpression cells. the mechanism was confirmed samples...
BACKGROUND Liver transplantation (LT) is the only curative treatment for end-stage liver disease. However, LT recipients are susceptible to infection, which leading cause of early mortality after LT. Klebsiella pneumoniae infections (KPIs) in bloodstream common recipients. We hypothesized that KPIs and carbapenem-resistant (CRKP) may affect outcomes AIM To assess KPI incidence, timing, distribution, drug resistance, risk factors following its association with outcomes. METHODS This...
Background Mesenchymal stem cells (MSCs) can alleviate graft-versus-host disease (GVHD) in hematopoietic cell transplantation (HSCT). MSCs-derived exosomes (MEXs) mirror the biological function of their parent cells. Whether MEXs GVHD like or not is unclear. In this study, we investigate effects on and graft-versus-leukemia (GVL) effect vitro HSCT animal models. Method MSCs were produced using bone marrow mononuclear (MNCs), separated from supernatants MSCs. Electron microscopy, western...
Abstract Hypertrophic ligamentum flavum (LF) is a main factor responsible for lumbar spinal stenosis (LSS); however, the exact mechanisms of pathogenesis these processes remain unknown. This study aimed to elucidate whether circular RNAs and microRNAs regulate LF LSS, especially focusing on circPDK1 (hsa_circ_0057105), circRNA targeting pyruvate dehydrogenase kinase 1 differentially expressed in tissues between disk herniation LSS patients. The circPDK1/miR‐4731 miR‐4731/TNXB (Tenascin XB)...
Feng J., Zhao N., Rabie A. B., Shen G. Orthopedic protraction of the maxilla may affect cranial base synchondroses indicated by increased expressions growth factors. Orthod Craniofac Res 2012; 15 :62–70 © John Wiley & Sons A/S Structured Abstract Objectives – To examine biological adaptation (CBS) when was forward positioned orthopedic force. Setting and Sample Population The Department Orthodontics at Shanghai Jiao Tong University. 50 Sprague–Dawley rats, 4 weeks age, were divided into...
目的 探讨苯并(a)芘[B(a)P]对大鼠海马细胞病理学和凋亡的影响.方法 健康雄性SD大鼠40只,麻醉后定位插管于侧脑室,随机分为橄榄油组(溶剂对照组)、B(a)P低剂量组(2.5mmol/L)、B(a)P中剂量组(5.0mmol/L)、B(a)P高剂量组(10.0mmol/L),每组8只.分别向高、中、低浓度绀缓慢注入B(a)P溶液10μl,溶剂对照组注入橄榄油10μl.每周给药1次,共3周.染毒结束取肭组织,光学显微镜和电子显微镜下观察海马神经细胞肜态,原位末端标记(TuNEL)法检测海马细胞凋亡.结果 病理结果 显示,随着B(a)P染毒剂量的增高,出现典型的神经细胞损伤现象,中、高剂量组海马神经细胞出现排列紊乱,数目减少,胞浆透明,核皱缩,细胞周围出现环状带.电子显微镜结果...
Susceptibility-weighted imaging (SWI) is a common technique used to identify cerebral microbleeds. Given that spinal cord injury (SCI) often creates an environment favors ferroptosis, type of cell death driven by iron, this study aimed explore the relationship between microbleeds on SWI and effect deferoxamine SCI.
Background: The cracking load is an important parameter in the design and testing of beam structures according to recent patents. Compared ordinary concrete, recycled aggregate concrete components are more prone cracking. Methods: In this paper, calculation method size effect for were studied. Four beams with different sizes tested by four-point bending experiment obtain their loads. According comparison values calculated two existing methods, it was found that methods only suitable...
Objective To explore the effects of hemoperfusion on coagulation function with acute poisoning patients.Methods Coagulation index,amount platelet and clinical hemorrhage events were detected observed in 32 cases patients before after hemoperfusion(HP).Results The amounts platlet significantly reduced one hour HP treatment(P ＜ 0.05),coagulation index was not changed except that D-D dimers elevated(P 0.05) ; 6 presented significant bleeding,15 forced to terminate treatment due...